spherical agglomerates
Preparation and Characterization of Spherical Agglomerates of Gliclazide
... by spherical agglomeration method in the presence of hydrophilic polymer such as PVP K30 and PEG ...the spherical agglomerates of gliclazide consist of ethanol (good solvent), water (poor solvent) ...
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PREPARATION AND CHARACTERIZATION OF GLIPIZIDE SPHERICAL AGGLOMERATES BY DIRECT COMPRESSION METHOD USING DIFFERENT POLYMERS AND ITS EVALUATION
... glipizide spherical agglomerates with improved solubility, flow and compression characteristics by novel crystallization ...40°C. Spherical agglomerates were characterized by IR spectroscopy, ...
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DESIGN AND DEVELOPMENT OF DANTROLENE SPHERICAL AGGLOMERATES FOR IMPROVEMENT IN BIOAVAILABILITY
... of agglomerates represented in terms of the angle of repose, Carr’s index and Hausner ...the spherical agglomerates, this could be due to their regular shape which hindered in the uniform flow of ...
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“Preparation and Characterization of Spherical Agglomerates of Tenoxicam” by Mudit Dixit, Meghana Rao S, R Narayana Charyulu, Anupama Shetty, Sharin Thomas, Pallavi Bengre, India.
... prepare spherical agglomerates (SA) of Tenoxicam by solvent change ...for spherical agglomerates of Tenoxicam consisted of DMF: Water and ...the spherical agglomerates was ...
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Design and evaluation of sustained release spherical agglomerates of Fluvastatin sodium by crystallo-co-agglomeration
... release spherical agglomerates containing Fluvastatin Sodium by crystallo-co-agglomeration and to evaluate the prepared agglomerates for micromeritic, mechanical and compression properties and ...
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DEVELOPMENT AND CHARACTERIZATION OF CONTROLLED RELEASE SPHERICAL AGGLOMERATES BY USING THE QUASI-EMULSION SOLVENT DIFFUSION METHOD
... grade. Spherical Crystallization [9-11] : Quasi emulsion solvent diffusion method were used to obtained spherical agglomerates in which the, aspirin (1 gm) was dissolved in ...prepared ...
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Development and Validation of Method for the Estimation of Telmisartan as Active Pharmaceutical Ingredient in Tablet Dosage form and Prepared Spherical Agglomerates by RP-HPLC
... Abstract The Present work was designed to develop and validate an accurate, precise and rapid method for the estimation of Telmisartan as Active Pharmaceutical Ingredient (API) as well as in tablet dosage form and ...
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FORMULATION AND IN VIVO EVALUATION OF RISPERIDONE SPHERICAL AGGLOMERATES PREPARED FOR EARLIER ABSORPTION OF RISPERIDONE
... prepared spherical agglomerates equivalent to 10 mg of RES were carried out with the USP dissolution method type II using USP dissolution testing apparatus (Pharma Test, PTW, Germany) at 37 ± ...
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Preparation And Characterization Of Spherical Agglomerates Of Ibuprofen By Neutralization Method
... powder. Spherical agglomeration is one of such techniques to improve the micromeritic properties and dissolution of ...drug. Spherical agglomeration process is a multiple unit process in which ...
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DESIGNING & DEVELOPMENT OF SPHERICAL AGGLOMERATES OF IBUPROFEN-PARACETAMOL BLEND FOR IMPROVED TABLETING AND DISSOLUTION
... Bulk density and tapped densities of SAPI were 0.654gm/cm 3 and 0.765g/cm 3 respectively when compared with untreated blend of drugs (0.457 and 0.722 gm/cm 3 ). This showed that agglomerated Table-2 Micromeritics ...
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Formulation and Evaluation of Directly Compressible Agglomerates of Telmisartan
... These characteristic peaks of the drug were also observed in spectrum of the formulation. So presence of these characteristic peaks of telmisartan in physical formulation reveals that the drug remains intact in ...
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APPLICATION OF SPHERICAL AGGLOMERATION TECHNIQUE TO IMPROVE MICROMERITIC PROPERTIES AND DISSOLUTION CHARACTERISTICS OF NABUMETONE
... X-ray powder diffractometry (XRPD) is a powerful technique for the identification of crystalline solid phases. Every crystalline solid phase has a unique XRPD pattern, which can form the basis for its identification. The ...
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Modification of physicochemical and micromeritic properties of active pharmaceutical ingredient by crystallization technique
... on spherical crystalisation of celecoxib, to optimise the experimental conditions for obtaining spherical agglomerates, and to study the various properties of prepared ...by spherical ...
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“DEVELOPMENT OF DIRECTLY COMPRESSIBLE METFORMIN HYDROCHLORIDE TABLETS” by Gadekar Shrikant*, Kavade Vishal, Kale Vinita, India.
... MH agglomerates prepared by spherical crystallization techniques, ...of agglomerates, represented in terms of the angle of repose and change in tapping density, were much improved by this technique ...
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SPHERICAL CRYSTALLIZATION OF ZALTOPROFEN FOR ENHANCEMENT OF MICROMERITIC PROPERTIES AND DISSOLUTION RATE
... a spherical shape 3 . Agglomerates exhibit improved secondary characteristic like flowability and compressibility so that direct tableting is possible without further ...that spherical crystals can ...
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FORMULATION AND EVALUATION OF SPHERICAL CRYSTAL AGGLOMERATES OF NISOLDIPINE
... Drug Content: For determination of drug content the Spherical agglomerates of nisoldipine equivalent to 100 mg of nisoldipine was triturate and dissolved in methanol. Appropriately diluted sample was ...
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FORMULATION & EVALUATION OF SPHERICAL CRYSTAL AGGLOMERATES OF CANDESARTAN CILEXETIL
... A quasi-emulsion solvent diffusion method was adopted for preparation of spherical agglomerates of Candesartan Celexetil using Acetone as a good solvent and water as a poor solvent. Dichloromethane was ...
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CRYSTALLO-CO-AGGLOMERATION: A NOVEL TECHNIQUE TO IMPROVE FLOW AND COMPRESSIBILITY
... The spherical crystallization could shorten the manufacturing process in tabletting, so that the cost and time of manufacturing of the tablets could be ...the spherical agglomeration ...of ...
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“SPHERICAL AGGLOMERATION OF KETOPROFEN BY SOLVENT CHANGE METHOD” Mudit Dixit*, Dr.P. K. Kulkarni and Ashwini G Kini, India.
... properties. Spherical agglomerates were prepared by solvent change ...for spherical agglomeration was determined by constructing ternary ...for spherical agglomerates of ketoprofen ...
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Crystallo co-agglomeration-a review
... the agglomerates diffuses to the organic solvent, its capability to act as a bridging liquid weakens and subsequently spherical agglomerates are formed [12] ...
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