Structural insights into MATα and MATβ proteins
Telomerase and Telomere-Associated Proteins: Structural Insights into Mechanism and Evolution
... our structural understanding of telomerase and telomere-associated proteins have contributed significantly to elucidating the molecular mechanisms of telomere ...valuable insights into how ...
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From DNA to proteins via the ribosome: Structural insights into the workings of the translation machinery
... Yet, despite the wide-scale efforts and widespread interest, our knowledge of the mechanisms govern- ing protein synthesis by the ribosome has remained incomplete. Progress toward an understanding of the mechanism of ...
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Structural insights into the inactivation of CRISPR-Cas systems by diverse anti-CRISPR proteins
... essential structural role in complex assembly, resembling a string and tethering the protein subunits of this complex together ...and structural information, we know that two AcrF1 proteins sit on ...
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CiteSeerX — MINIREVIEW Receptor-Mediated Activation of Heterotrimeric G-Proteins: Current Structural Insights
... the structural basis for this ubiquitous event of receptor GEF ...the structural determinants for complex formation between re- ceptor and heterotrimer, allowing one to manipulate one or more aspects of ...
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New Structural Insights into the Genome and Minor Capsid Proteins of BK Polyomavirus using Cryo-Electron Microscopy
... In this study, we extend existing observations from a range of disparate systems and bring them together in the study of a sin- gle, pathogenic human polyomavirus. We present the first sub- nanometer-resolution solution ...
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Structural Insights into Human Bocaparvoviruses
... Comparative structural analysis of these viruses suggests a previously identified VR, VR-III, as a determinant of tissue tropism, while comparison to the previously reported BPV structure identified VR-VI to VR-VIII ...
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Structural genomics of membrane proteins
... membrane proteins typically maintain not only their secondary and tertiary structure, but also their quaternary structure within ...membrane proteins can be characterized in aligned planar bilayers by using ...
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Predicting structural domains in proteins
... Hydrophobic collapse and domain formation then used to convert the positional boundary scores for the 1 0 0 test models into Z-scores {{x — m )/a ). Average positional scores were calculated for the sets of test and ...
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IDENTIFYING STRUCTURAL DOMAINS IN PROTEINS
... tested proteins and, hence, that it performs as well as the best of the above-mentioned three ...splits proteins into two domains that are considered a single architecture by ...
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Evolutionary and structural analyses of alpha papillomavirus capsid proteins yields novel insights into L2 structure and interaction with L1
... capsid proteins as well as minor capsid proteins of alpha- papillomavirus that have been evolutionarily conserved, and define regions that are under constant selective pres- sure with respect to the entire ...
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Structural Insights into Calicivirus Attachment and Uncoating
... Medical Research Council Virology Unit, Glasgow University, Church St., Glasgow G11 5JR, United Kingdom, 1 and Department of Virology, Faculty of Medicine, Imperial College London, Norfolk Place, London W2 1PG, United ...
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Insights into the structural biology of Gaucher disease
... in structural stability and catalytic activity however, it remains difficult to predict disease severity based on mutation location as understanding of how the structural defects caused by specific ...
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Structural insights into regulation of gene expression
... The electron density reveals a well-defined C-terminal domain and partially an N-terminal domain. A weak electron density for the N-terminal domain can be observed, however it is not sufficient for building a model ...
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Placement of the Structural Proteins in Sindbis Virus
... Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907-1392 Received 23 May 2002/Accepted 8 August 2002 The structure of the lipid-enveloped Sindbis virus has been determined by fitting ...
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Structural Investigation of Binding Events in Proteins
... 2 component of binding substrates, performing enzymatic catalysis, and releasing bound substrates. 4-5 Studying the flexibility of proteins and their binding sites has yielded some key insights of what ...
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Lamins are the major structural proteins of the nuclear
... Additional changes in the structural organization of neuronal nuclei in homozygous lam P animals were dis- closed by electron microscopy. First, we frequently ob- served incomplete or even missing nuclear ...
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Structural features of tight-junction proteins
... conformation of the carboxylate-binding loop. 346 Figure 7. Structural features of PDZ domains. (a) Topology of a prototypical PDZ domain, here PALS 1 PDZ, PDB entry 4UU6 [87]. The polypeptide chain is drawn in ...
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EVIDENCE OF CHROMOSOMAL BREAKS NEAR THE MATING-TYPE LOCUS OF SACCHAROMYCES CEREVISIAE THAT ACCOMPANY MATα x MATα MATINGS
... In examples A and B, we presume that the mitotic cell receives one intact and one broken chromosome (which is then lost). In C, a cell becomes a stable diploid by inheriting [r] ...
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Structural Proteins of Reoviruses
... Electron microscopic examination of purified reovirus particles has shown that all serotypes consist of three principal morphological com- ponents: (i) the outer capsid, (ii) an inner st[r] ...
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The structural proteins of influenza virus
... immune serum of proven specificity for the RNP, analytical polyacry- lamide gels were better guides to the progress of internal antige n purification. 2) A more se[r] ...
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