suppressor mutations
THE DETECTION OF REVERSE MUTATIONS AT THE mtr LOCUS IN NEUROSPORA AND EVIDENCE FOR POSSIBLE INTRAGENIC (SECOND SITE) SUPPRESSOR MUTATIONS
... No.. BRINK et al. histidine revertants while producing very large numbers of mtr+ revertants. The alkylating agents EMS and DES caused low frequencies of hist+ and rather high fr[r] ...
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SUPPRESSOR MUTATIONS FOR THE ISOLEUCINE LOCUS IN SACCHAROMYCES
... four independent revertants were found. These were crossed to haploid isl-, strains for evidence of suppressors and specificity. Thus the four revertants were due to [r] ...
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SUPPRESSOR MUTATIONS IN SOME CYSTINE-REQUIRING MUTANTS OF SALMONELLA TYPHIMURIUM
... To summarize, the genetic analysis showed that the small colony “revertant” of the multisite mutant cys-20 carries a suppressor mutation, su-1, which is ap- parently not cl[r] ...
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BIOCHEMICAL DEFINITION OF YELLOW-VIRESCENT AND LIGHT-GREEN SUPPRESSOR MUTATIONS IN BARLEY
... Chlorophyll content, free amino acids, and soluble leaf proteins were studied in barley seedlings of wild type, an X-ray induced yellow-virescent mutant, and an X-ray induced light-g[r] ...
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MAP POSITIONS AND SPECIFICITIES OF SUPPRESSOR MUTATIONS IN ESCHERICHIA COLI K-12
... (lacZ13) has also been reported by BECKWITH (1963b). Tests for suopression of ilv-188 by nonsense suppressors: As suppressors of ilv-188 were found to be capable of supp[r] ...
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Mutations in the Influenza A Virus M1 Protein Enhance Virus Budding To Complement Lethal Mutations in the M2 Cytoplasmic Tail
... M1 suppressor mutations are located at 7 distinct positions of the protein and are present in the N-terminal, middle, and C-terminal regions of the protein (yellow lines, ...M1 suppressor ...
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Selection of Reversions and Suppressors of a Mutation in the CBF Binding Site of a Lymphomagenic Retrovirus
... the mutations in the So and T* cores increased binding of CBF and increased transcriptional activity of the viral LTR ...these mutations are repeatedly ...resent suppressor mutations within ...
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INTERACTION OF DNA POLYMERASE III γ AND β SUBUNITS IN VIVO IN SALMONELLA TYPHIMURIUM
... A possible alternative or additional role for y was proposed by WALKER on the basis of suppressor mutations occurring in the initiation gene, dnaA, di- rected aga[r] ...
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Analysis of Dominant Enhancers and Suppressors of Activated Notch in Drosophila
... Novel complementation groups: In addition to re- covering enhancer and suppressor mutations in known genes, including members of the Notch pathway and.. TABLE 3.[r] ...
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Recombinogenic Effects of Suppressors of Position-Effect Variegation in Drosophila
... PEV suppressor mutations for their effects on crossing over in pericentromeric regions of Drosophila ...46 mutations (28 loci) studied, 16 Su(var) mutations of the nine genes Su(var)2-1, ...
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FRAMESHIFT SUPPRESSION IN SACCHAROMYCES CEREVISIAE. II. GENETIC PROPERTIES OF GROUP II SUPPRESSORS
... These “up-frameshift suppressor” mutations have been characterized by (1) their inability to act as autonomous suppressors of frameshift mutations in the absence of a framesh[r] ...
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INDIRECT SUPPRESSION IN CAENORHABDITIS ELEGANS
... I n the case of suppression of muscle defects we have characterized a number of independent suppressor mutations that are judged to be alleles of sup-3 on the following basis: [r] ...
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A genetic analysis of suppressors of the PF10 mutation in Chlamydomonas reinhardtii.
... Suppressor mutations at two of the seven loci (LIS1 and LIS2) require light for their suppressor activity.. Forty-eight of the 70 extragenic suppressors were examined in heteroz[r] ...
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Critical Role of Conserved Hydrophobic Residues within the Major Homology Region in Mature Retroviral Capsid Assembly
... The ability of the A38V mutation in the NTD to efficiently suppress the assembly defect caused by both the L171V and F167Y mutations in the CTD suggests that an NTD-CTD interaction is essential for the initiation ...
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Interaction of nonsense suppressor tRNAs and codon nonsense mutations or termination codons
... tRNA suppressor into mdx mice, dystrophin positive fibers were detected by sarcolemmal immu- ...tRNA suppressor gene might be a useful in vivo treatment for the genetic disorders caused by nonsense ...
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Mitochondria, cholesterol and cancer cell metabolism
... degradation through the ubiquitin–proteasome path- way. Under oxidative stress or through particular chemi- cal inducers, cysteine residues of KEAP1 are modified and the resulting conformational change leads to the ...
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Molecular pathogenesis of sporadic colorectal cancers
... Previously, hyperplastic polyps were considered non- neoplastic, but some are now considered precursors of CRC. Therefore, hyperplastic polyps were renamed “serrated polyps,” which the World Health Organization now ...
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STREPTOMYCIN RESISTANCE IN ESCHERICHIA COLI ANALYZED BY TRANSDUCTION
... If two independent suppressor mutants represented mutations at two different gene loci, not closely linked, reciprocal transduction experiments between them would be expected to [r] ...
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THE GENETICS OF A SMALL AUTOSOMAL REGION OF DROSOPHILA MELANOGASTER CONTAINING THE STRUCTURAL GENE FOR ALCOHOL DEHYDROGENASE. III. HYPOMORPHIC AND HYPERMORPHIC MUTATIONS AFFECTING THE EXPRESSION OF HAIRLESS
... p u s and allele specific suppressor and enhancer mutations are well known in Drosophila melanogaster, although there is little evidence for any particu- lar example of the[r] ...
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Submicroscopic deletion of 5q involving tumor suppressor genes (CTNNA1, HSPA9) and copy neutral loss of heterozygosity associated with TET2 and EZH2 mutations in a case of MDS with normal chromosome and FISH results
... gene mutations in myeloid ...tumor suppressor candidate genes (CTNNA1 and HSPA9) that are associated with ...revealed mutations in TET2 (4q), EZH2 (7q), ...
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