T cell migration
Purinergic P2X4 receptors and mitochondrial ATP production regulate T cell migration
... regulates T cell ...resting T cells (26). In activated T cells, a burst of mitochondrial activity promotes T cell receptor signaling at the immune synapse between T cells ...
13
Cognate antigen directs CD8+ T cell migration to vascularized transplants
... The migration of effector or memory T cells to the graft is a critical event in the rejection of transplanted ...in T cell migration — integrin-mediated firm adhesion followed by ...
10
Phosphorylation of Rab5a protein by protein kinase Cϵ Is crucial for T cell migration
... affected T-cell migration, we investigated the mech- anistic basis of this migratory ...HuT-78 T-cells demonstrated punctate and globular structures evenly distributed throughout the whole ...
16
Monocytes Regulate T Cell Migration through the Glia Limitans during Acute Viral Encephalitis
... Leukocyte migration through the endothelial cell wall into the perivascular space is well characterized; however, mechanisms regulating their penetration through the glia limitans into the parenchyma are ...
11
Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1
... T cell recruitment and differentiation can be used to assess the efficiency of MSC-mediated ...lymphocyte migration can aggravate local inflammation and the progression of some diseases [31, ...
13
CRK proteins selectively regulate T cell migration into inflamed tissues
... (GVHD). T cell migration into such sites depends heavily on regulated adhesion and migration, but the signaling pathways that coordinate these functions downstream of chemokine receptors are ...
15
Phosphorylation of Rab5a Protein by Protein Kinase Cϵ Is Crucial for T cell Migration
... affected T-cell migration, we investigated the mech- anistic basis of this migratory ...HuT-78 T-cells demonstrated punctate and globular structures evenly distributed throughout the whole ...
19
Phosphoinositide 3 kinase and the mammalian target of rapamycin pathways control T cell migration
... that mTOR regulation of CD62L and CCR7 expres- sion may be important for the immunosuppres- sive actions of the mTORC1 inhibitor rapamycin, which is widely used clinically as an immunosup- pressant. It was originally ...
9
Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus
... encephalitogenic T cell migration over endothelial barriers, MCAM blockade impeded encephalitogenic T cell migration in murine models of MS that especially depend on CNS ...
12
Metabolism, migration and memory in cytotoxic T cells
... + T cells? One explanation could be the ability of rapamycin to reprogram the trafficking of effector CTLs such that these cells regain the ability to enter secondary lymphoid tissue 17, 75 ...memory T ...
21
RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion
... suppresses cell migration through modulation of the PTEN/PI3K/Akt signaling pathway ...at cell-cell junctions ...glioblastoma migration and ...
13
Original Article MiR-320a inhibits cell proliferation and metastasis of esophageal squamous cell carcinoma cell lines by targeting CBX3
... TE10 cell line was detected by qRT-PCR ...ESCC cell line com- pared with normal esophageal Het-1 A ...TE10 cell line was co-transfected with PsicheckTM-2-CBX3-WT and miR-320a mimi- cs (Figure ...when ...
6
Original Article Long noncoding RNA NORAD regulates lung cancer cell proliferation, apoptosis, migration, and invasion by the miR-30a-5p/ADAM19 axis
... the cell growth, migration, and inva- sion, andcontributed to apoptosis in lung can- cer ...repressed migration and invasion of NSCLC cells ...proliferation, migration, and invasion abilities ...
13
L1cam promotes tumor progression and metastasis and is an independent unfavorable prognostic factor in gastric cancer
... cellular migration, invasion and apoptosis resistance ...stimulated cell motility via binding to integrin receptors, activating FAK, and increasing turnover of focal complexes ...enhance cell ...
14
The function of a novel guidance molecule, Plexin-A1, on immune dendritic cells
... T cell stimulation by DCs lacking PlxnA1 not only confirmed the results of the PlxnA1-Fc blocking assays, but also demonstrated the grave consequences to T cell proliferation resulting from ...
154
The effect of aging and caloric restriction on murine CD8+ T cell chemokine receptor gene expression
... CD8+ T cells, or cytotoxic T lymphocytes, are essential members of the immune system involved in tumor sur- veillance and in combating viral ...CD8+ T cells in aging, including elevated percentage ...
10
miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3
... In the present study, we demonstrated that miR-222-3 p was upregulated in OS tissues and OS cell lines. In addition, inhibition of miR-222-3p can suppress OS cell proliferation, colony formation, and ...
11
Novel immune cell-based therapies for atherosclerosis
... To determine atherosclerotic plaque size, 10 µm cryosections of the aortic root were stained with Oil-Red-O and hematoxylin (Sigma-Aldrich). Corresponding sections were stained for collagen fibers using the Masson’s ...
215
Primordial germ cell migration
... PGC migration in flies can be divided into four stages, internaliza- tion of the pole cells (1), emigration of PGCs from the gut (2), lateral migration of PGCs (3) and gonad coalescence (4) ...of ...
8
Recirculation of Innate Lymphocyte Subsets in the Skin
... Intact female or wethers of mixed breed sheep, 5-10 months of age, were purchased from 3/D Livestock (Woodland, CA), the University of California, Davis (Davis, CA), Animal Biotech Industries (Danboro, PA), or Pine Ridge ...
145