T helper 17 cells (Th17)
Decreased T helper 17 cells in tuberculosis is associated with increased percentages of programmed death ligand 1, T helper 2 and regulatory T cells
... + T lymphocytes through interactions between programmed cell death ligand-1 (PD-L1) from dendritic cells and PD-1 on T cells ...of T cell regulators, and the intracellular tail con- ...
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Interleukin-17 and type 17 helper T cells in cancer management and research
... discovery, T helper 17 (Th17) cells have been frequently detected in the tumor microenvironment of many malignancies, but their clinical implications remain largely ...of Th17 ...
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Transcriptional Regulation of T Helper 17 Cell Differentiation
... IL-17-producing Th17 cells in autoimmune responses and the regulatory mechanisms for Th17 cell differentiation, a new paradigm of Th cell differentiation has been ...Th1/Th2/ ...
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Th1/17 Polarization of CD4 T Cells Supports HIV-1 Persistence during Antiretroviral Therapy
... and Th17-polar- ized CD4 T helper cells, with or without concomitant expression of the Tfh surface marker CXCR5, to identify polarization condi- tions of helper CD4 T ...
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The pro-inflammatory potential of T cells in juvenile-onset systemic lupus erythematosus
... + T cells are known to regulate B cell autoantibody production through provision of co- stimulatory signals and cytokines ...individual T cell subsets in JSLE whilst central to dis- ease progression ...
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Abnormal T regulatory cells (Tregs: FOXP3+, CTLA 4+), myeloid derived suppressor cells (MDSCs: monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC
... Th17 cells play a crucial role in inflammation and autoimmunity, but their function in cancer is unclear ...tumour cells by induction of Th1 lymphocytes and CTL antitumour responses ...induce ...
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Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis
... T helper 17 (Th17) cells have also been proposed to have a relevant role in the early phase of RA through the production of IL-17 ...of Th17 cells and neutrophils ...
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Relationship of redundant Th17 cells and IL-17A, but not IL-17 F, with the severity of obstructive sleep apnoea/hypopnoea syndrome (OSAHS)
... Th17 cells, a recently discovered subset of T helper cells with a highly inflammatory nature, can secrete several potent proinflammatory cytokines, including IL-17A and IL-17 F, ...
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Inflammatory and T Helper 17/ Regulatory T Cells Related Cytokines Balance in Cutaneous Lupus Erythematosus (CLE)
... reactive T cells by secreting inhibitory cytokines such as TGF-β and IL-10 or through direct ...proinflammatory Th17 cells to Treg cells plays an important role in the pathogenesis of ...
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Alveolar T helper 17 responses to streptococcus pneumoniae are preserved in ART untreated and treated HIV infected Malawian adults
... alveolar Th17 responses against ...Serotype-independent T cell- based pneumococcal vaccines that focus solely on inducing a robust Th17 response may not promote clearance of lung infection and ...
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The association between single nucleotide polymorphism in interleukin-27 gene and recurrent pregnancy loss in Iranian women
... of Th17 cells (10, 11). It has been shown that IL-27 suppresses IL-17 production by activated CD4 + T ...producing T helper cells ...suppresses T-cell responses or ...
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Altered peptide ligands inhibit arthritis induced by glucose 6 phosphate isomerase peptide
... exact helper T-cell lineage critical in RA remains elusive, previous animal studies reported that Th17 cells play a crucial role and that Th1 cells may have a protective role against ...
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Cytokine profile and induction of T helper type 17 and regulatory T cells by human peripheral mononuclear cells after microbial exposure
... our study showed a balance between these cells, representative of that found in a healthy donor [48]. Previously Lb. acidophilus strain LAVRI-A1 had no clinical effect on eczema [94]; however this strain may be ...
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Frequency of circulating topoisomerase I specific CD4 T cells predicts presence and progression of interstitial lung disease in scleroderma
... implicating T cells in this response [11, ...antigen-driven, T cell-dependent process in SSc is supported by several studies ...topo-I-reactive T cells would be relevant to determine ...
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Dynamic interactions between T cells and dendritic cells and their derived cytokines/chemokines in the rheumatoid synovium
... dendritic cells (DCs) and T cells, and by local production of cytokines and chemokines to the pathogenesis of rheumatoid arthritis (RA) ...presenting cells, which are critical for the ...
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The role of T cell subsets in experimental autoimmune encephalomyelitis
... auto-reactive T cells into the CNS ...reactive T cell populations into naive mice and these mice will develop clinical symptoms; this model is useful in the determination of which cell types are ...
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Epitope-Specific CD8+ T Cells Play a Differential Pathogenic Role in the Development of a Viral Disease Model for Multiple Sclerosis
... embedded in Epon. Sections were cut at a 1- m thickness, stained with toluidine blue, and analyzed by microscopy (44). Ten different sections of the lumbar region of the spinal cord of individual mice (two mice per ...
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The clinical importance of changes in Treg and Th17 lymphocyte subsets in splenectomized patients after spleen injury
... mononuclear cells were stained with anti-CD3 Cy- Chrome and anti-CD4 fluorescein-isothiocyanate (FITC) conjugated monoclonal antibodies (Becton Dickinson, San Diego, ...the cells were washed twice with PBS. ...
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Helper T cells in flavivirus infection
... Recently the YF, West Nile dengue type 2 al., DEN2 encephalitis of yellow fever Rice et amino {SLE and virus genomes have been investigated 1985, 1986; Dalgarno et al., 1986a; amino-term[r] ...
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Interleukin 1 (IL-1)- and IL-23-Mediated Expansion of Filarial Antigen-Specific Th17 and Th22 Cells in Filarial Lymphedema
... of Th17 cells and the recently described Th22 cells have not been examined in detail in either filarial infection itself or in filarial disease ...of Th17 and Th22 cells and their ...
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