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The neural crest

The neural crest

The neural crest

... The neural crest (NC) is a highly migratory multipotent cell population that forms at the interface between the neuroepithelium and the prospective epidermis of a developing ...

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Recycling signals in the neural crest

Recycling signals in the neural crest

... cranial neural crest caused a cleft secondary palate, non-formation of the calvaria (the dome of the skull), and other skull ...cranial neural crest occurred normally, a study of ...

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The generation of adipocytes by the neural crest

The generation of adipocytes by the neural crest

... the neural crest ...After neural tube closure, NC cells undergo an epithelio-mesenchyme transition and migrate to diverse regions in the developing ...

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Tcf7l1 protects the anterior neural fold from adopting the neural crest fate

Tcf7l1 protects the anterior neural fold from adopting the neural crest fate

... The neural crest (NC) is crucial for the evolutionary diversification of ...the neural plate border by the coordinated action of several signaling pathways, including Wnt/ β - ...posterior ...

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LSox5 regulates RhoB expression in the neural tube and promotes generation of the neural crest

LSox5 regulates RhoB expression in the neural tube and promotes generation of the neural crest

... the neural crest, the upregulation of RhoB appears to be an immediate consequence of LSox5 misexpression in the neural ...the neural epithelium, the number of RhoB-expressing cells increases ...

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Progenitors of the protochordate ocellus as an evolutionary origin of the neural crest

Progenitors of the protochordate ocellus as an evolutionary origin of the neural crest

... the neural crest evolutionary origin in this basal animal ...rudimentary neural crest in ascidians, we do not see the evolutionary scenario of ocellus-to-neural crest ...

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New genes in the evolution of the neural crest differentiation program

New genes in the evolution of the neural crest differentiation program

... on neural crest evolution Our understanding of how developmental regulatory path- ways evolved in metazoans is now building upon steadily accumulating sequence collections that cover representative ...

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Ancient Evolutionary Origin of the Neural Crest Gene Regulatory Network

Ancient Evolutionary Origin of the Neural Crest Gene Regulatory Network

... of neural crest modules to the network occurred prior to separation of jawed and jawless verte- brates, likely during the transition from protochordates to ...lamprey neural crest, but exist ...

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Experiments on the Neural Crest of the Lamprey Embryo

Experiments on the Neural Crest of the Lamprey Embryo

... The defect experiments cannot be said to prove the non-crest origin of the lamprey visceral skeleton, but it is fair to conclude from them that it is unlikely that either the branchial b[r] ...

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Hoxa2 downregulates Six2 in the neural crest derived mesenchyme

Hoxa2 downregulates Six2 in the neural crest derived mesenchyme

... Final evidence that repression of Six2 is one of the mechanisms employed by Hoxa2 in second arch patterning will require analysis of a Hoxa2; Six2 double mutant. Our prediction is that Six2 inactivation should, at least ...

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Insights into Neural Crest Evolution

Insights into Neural Crest Evolution

... The neural crest of jawed vertebrates is divided into discrete subpopulations— cranial, vagal, trunk, and lumbosacral—distributed along the embryonic body axis with each following migratory pathways and ...

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The cardiac neural crest in Ambystoma mexicanum

The cardiac neural crest in Ambystoma mexicanum

... cardiac neural crest in Ambystoma mexicanum NAAZISH ...cranial neural crest contributes cells to the developing heart of Ambystoma mexicanum (axolotl), as it does in many other vertebrates, we ...

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Genetic Correlates of Neural Crest Evolution

Genetic Correlates of Neural Crest Evolution

... the neural plate. As neurulation begins, the neural plate may roll up to form the neural tube, or condense towards the dorsal ...the neural tube lumen then forms by cavitation of a solid ...

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Neural crest and septation of the embryonic heart

Neural crest and septation of the embryonic heart

... the neural crest migration defect in mutant embryos The cardiac phenotype, and other associated malformations o f Sp^^/Sp^^ embryos, all indicate a defect in neural crest cell ...the ...

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Early Neural Crest Specification, Induction and Competence

Early Neural Crest Specification, Induction and Competence

... for neural crest formation. Expression of the neural crest marker Slug was prevented by injecting COS cells expressing a dominant negative Wnt1 construct adjacent to the neural ...

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Uncovering Molecular Properties of Neural Crest Cells

Uncovering Molecular Properties of Neural Crest Cells

... the neural crest cell and the genetic control that it is ...to crest was compared to its component ...migratory neural crest were ...

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Neural crest derivatives in ocular and periocular structures

Neural crest derivatives in ocular and periocular structures

... of neural crest-derived myogenesis concerns ...of crest-derived mesenchyme at the lateral margin of the optic cup promotes and supports the outgrowth of ectodermal appendages fated to form the ...

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Genetic ablation of neural crest cell diversification

Genetic ablation of neural crest cell diversification

... INTRODUCTION The neural crest (NC) is an ectoderm-derived embryonic cell population induced at the neural plate border during gastrulation. NC cells subsequently delaminate from the neuroepithelium, ...

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Requirement for Foxd3 in the maintenance of neural crest progenitors

Requirement for Foxd3 in the maintenance of neural crest progenitors

... of neural crest progenitors Lu Teng 1, * ,† , Nathan ...neural crest. Using tissue-specific deletion of Foxd3 in the neural crest, we show that Foxd3 flox/– ; Wnt1-Cre mice die ...

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PDGF signalling during Neural Crest Cell migration

PDGF signalling during Neural Crest Cell migration

... brief, neural crest cell induction is initiated in the ectoderm by a combination of instructive signals between the presumptive neural plate and epidermis during ...the neural plate border ...

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