The pheromone response pathway
Identification and characterization of a mutation affecting the division arrest signaling of the pheromone response pathway in Saccharomyces cerevisiae.
... T h e phenotypic char- acteristics of the dac2 mutant suggest that the DAC2 product is involved in the division arrest signaling of t h e pheromone response pathway and, [r] ...
8
The pheromone receptors inhibit the pheromone response pathway in Saccharomyces cerevisiae by a process that is independent of their associated G alpha protein.
... Truncations that deleted a larger region of the cytoplasmic tail did not produce functional protein as determined by complementation of a ste3::LEU2 allele in MATa cells [r] ...
11
Relative Dependence of Different Outputs of the Saccharomyces cerevisiae Pheromone Response Pathway on the MAP Kinase Fus3p
... ABSTRACT Fus3p and Kss1p act at the end of a conserved signaling cascade that mediates numerous cellular responses for mating. To determine the role of Fus3p in different outputs, we isolated and characterized a series ...
20
Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade.
... Interaction between Ste5p and members of the MAP kinase cascade: The finding that Ste5p interacts with Stel l p , Ste7p and Fus3p suggests that one role of Ste5p in [r] ...
11
Site-directed mutations altering the CAAX box of Ste18, the yeast pheromone-response pathway G gamma subunit.
... Direct attempts to suppress other dominant negative STE18 alleles (WHITEWAY et al. WHITEWAY, unpublished observations). Thus it is possible that the Ste5 protein is l[r] ...
10
Genetic Relationships Between the G Protein βγ Complex, Ste5p, Ste20p and Cdc42p: Investigation of Effector Roles in the Yeast Pheromone Response Pathway
... wild-type or mutant WC42 expressed under GAL control. the average activity of two transformants tested t SEM.. Plasmids containing the indicated galactose-induced CDC42mutan[r] ...
15
MAP Kinase Regulation of the Candida albicans Pheromone Pathway
... the pheromone response pathway, we constructed a mating-competent cpp1 null mutant strain by identifying an MTL homozygous version of strain CP29-1-7L4 (14) by sorbose selection (16, ...in ...
14
Role of Cdc42-Cla4 Interaction in the Pheromone Response of Saccharomyces cerevisiae
... in pheromone-treated cells (22, ...the pheromone response ...the pheromone response pathway ...control pheromone-induced cell cycle arrest and MAP kinase ...restore ...
11
ras2 Controls Morphogenesis, Pheromone Response, and Pathogenicity in the Fungal Pathogen Ustilago maydis
... putative pheromone response pathway exhibit phenotypes that are similar to that of the ras2 ...less pheromone and are incapable of responding to pheromone produced by compati- ble ...
13
Systematic profiling of cellular phenotypes with spotted cell microarrays reveals mating pheromone response genes
... literature-associated pathway components, as well as strain reconstructions, allow us to estimate the false-positive rate of this ...known pathway compo- nents, three (BEM4 , ISY1 , SDS3 ) can be reasonably ...
9
The Glc7p-Interacting Protein Bud14p Attenuates Polarized Growth, Pheromone Response, and Filamentous Growth in Saccharomyces cerevisiae
... the pheromone response path- way and morphogenesis uncovered a mutant defective in Bud14p ...the pheromone response pathway and enhanced filamentous growth, suggesting an antagonistic ...
11
Mating in Saccharomyces cerevisiae: The Role of the Pheromone Signal Transduction Pathway in the Chemotropic Response to Pheromone
... Cells mutant for compo- nents of the mitogen-activated protein ( M A P ) kinase cascade (ste5, ste20, stell, ste7or fm? kssl) formed diploids at a frequency 1% that [r] ...
14
Identification of a Cell Death Pathway in Candida albicans during the Response to Pheromone
... to pheromone. In this work, we tested whether the phenomenon of pheromone-induced death (PID) also occurs in the opportunistic pathogen Candida ...to pheromone, but only opaque cells undergo the ...
12
A Caenorhabditis elegans Pheromone Antagonizes Volatile Anesthetic Action Through a Go-Coupled Pathway
... the response of the nematode ...elegans pheromone antagonizes the VA halothane. Acute exposure to pheromone rendered wild-type ...dauer pheromone blocked pheromone-induced resistance ...
12
Cell-to-cell variability in the yeast pheromone response: high throughput screen identifies genes with different effects on transmitted signal and response
... in pathway variation was in fact due to differences in reporter-derived cytosolic fluorescence between isolated, live cells and not a secondary consequence of cell aggregation, unusual shape, autofluorescence ...
58
A Filamentous Growth Response Mediated by the Yeast Mating Pathway
... of pheromone below this threshold have not been systematically ...mating pheromone undergo a novel cellular response: cells modulate their division patterns and cell shape, forming colonies composed ...
10
The Gα Subunit Signals through the Ste50 Protein during the Mating Pheromone Response in the Yeast Kluyveromyces lactis
... of pheromone to the G protein-coupled receptor triggers par- tial release of KlSte50p, which in conjunction with KlSte11p becomes available to form a stable complex with ...mating pathway is to bring ...
7
Sexual Pheromone Induces Diffusion of the Pheromone-Homologous Polypeptide in the Extracellular Matrix of Volvox carteri
... transduction pathway, which makes sense given that both wound healing and durable zygote formation, the ultimate consequence of sexual induction, occur as the results of a response to an adverse environment ...
6
Proline inhibition of a sea anemone alarm pheromone response
... When both eluates were compared with a distilled water control for alarm inhibition, only the proline spot was effective (x 2 = 5-83, P < 0-025), a r e s u l t indicating that prol[r] ...
10
Regulation of microtubular dynamics in response to pheromone in Schizosaccharomyces pombe.
... Abstract Schizosaccharomyces pombe cells have two polarised growth modes: an intrinsic vegetative growth mode, determined by an internal positioning mechanism and an extrinsic shmooing growth mode, activated by external ...
244