The Wnt signalling pathway
WNT signalling pathway in oral lesions
... regulate WNT signalling in potentially malignant oral lesions and to analyse the re ce nt a d va nc em e nts t hat w ill im p ro ve o ur understanding in the identification of therapeutic biomarkers for ...
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The WNT signalling pathway in colorectal cancer
... 27 The armadillo repeat region comprises seven 42aa repeats spanning codons 453 to 767, showing homology with β-catenin and its Drosophila homologue (181). Armadillo repeats are present in various proteins with ...
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Non-digestible carbohydrates, the WNT signalling pathway and bowel cancer risk
... canonical WNT signalling pathway, due to its role in colon cancer aetiology, in colonic epithelial ...of WNT target genes when bound to β-catenin following β-catenin translocation to the ...
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Original Article Low expression of Dapper1 induces malignancy via the Wnt signalling pathway and is associated with poor prognosis in gastric cancer
... The Wnt signalling pathway is abnormally activated in gastric cancer as well as many other ...the Wnt signalling pathway in gastric ...canonical Wnt-signalling ...
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Regulation of neuritogenesis in neuroblastoma cells by components of the Wnt signalling pathway
... Since treatment of Neuro-2a cells with Li"^ upregulates nuclear P-catenin, this treatment was expected to increase P-catenin/TCF-dependent transcription. Using a TCP- responsive reporter plasmid, this was found to be the ...
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Wnt signalling in lung development and diseases
... PCP pathway In the PCP pathway, activation of Dvl leads to JNK, and in turn to AP1 activation ...canonical Wnt signalling pathway in the ...
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Wnt signalling during limb development
... the Wnt pathway has been associ- ated with ...of Wnt function is essential for both skeletal development and maintenance of the skeleton in the ...the Wnt signalling ...
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Wnt signalling and cancer stem cells
... Wnt signalling and disease Metabolic disease The Wnt signalling pathway has a signifi cant role in cellular metabolism, especially in disorders that involve diabetes mellitus ...
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Wnt signalling in endocrine resistant breast cancer
... the Wnt signalling pathway are deregulated in a model of tamoxifen-resistant breast cancer versus their endocrine sensitive counterparts, we next wished to investigate whether Wnt ...
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Connective tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex
... non-canonical WNT signalling The above experiments indicate that CTGF can inhibit the canonical WNT signalling pathway involving ...independent WNT signalling. ...
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The role of WNT signalling in chronic kidney disease (CKD)
... canonical Wnt signalling pathway via DKK1 treatment, which also inhibited TRPC6 expression ...canonical Wnt signalling pathway could cause podocyte dysfunction ...canonical ...
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Wnt signalling is a bi-directional vulnerability of cancer cells
... canonical Wnt signalling pathway but simultaneously provided a predictive gene signature to inform personalised treatment strategies that harness Wnt modulating ...
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The interaction of Wnt-11 and signalling cascades in prostate cancer
... androgen signalling, which drives tumour growth, however, they provide limited survival benefits for ...The Wnt signalling pathway induces expression of target genes through cell surface ...
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Molecular genetics of intracranial meningiomas with emphasis on canonical Wnt signalling
... of Wnt signalling pathway genes and proteins in this common brain tumour, describing their known functional ...multiple signalling pathways including Wnt pathway contribute to ...
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Studies of the Wnt/Beta-catenin signalling pathway in chronic myeloid leukaemia
... the Wnt pathway was responsible for regulating the activity of ...a Wnt pathway inhibitor [192], and WNT-3A which functions as a Wnt pathway ...
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Wnt signalling: conquering complexity
... the Wnt pathway from a developmental biology ...of Wnt signalling and discuss its impact on current clinical research and the progress of novel therapeutic ...‘ Wnt/ β -catenin ...
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WNT signalling in prostate cancer
... canonical WNT signalling and activated noncanonical WNT signalling have been ...target WNT signalling at different levels of the pathway have been developed, and some of ...
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The Wnt/β-catenin signalling pathway and anterior/posterior patterning in the vertebrate central nervous system
... About one hour after fertilisation, the superficial layer o f the egg rotates in relation to the inner part of the egg. This movement, called cortical rotation, displaces a maternal signalling centre that is ...
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RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer
... the Wnt/β-catenin signalling pathway ...Wnt4 signalling target, and RUNX1 and Wnt4 are mutually interdependent in their expression in ovary cells ...that Wnt/β-catenin signalling ...
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Wnt Signalling During F9 Cell Differentiation
... canonical WNT/β- catenin signalling pathway, and specifically the role of FZD receptors, in specifying a set of naïve cells to adopt an epithelial state known as primitive ...and WNT/Ca 2+ ...
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