Thyroid cancer cell lines
Effects of prolonged exposure to low dose metformin in thyroid cancer cell lines
... significant dose (affecting proliferation) dropping from 5 mM at day 3 to 1 mM metformin at day 14 significantly inhibiting colony formation (figures 1 and 2). The effects of metformin on clonogenicity have been ...
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Berberine Inhibited the Growth of Thyroid Cancer Cell Lines 8505C and TPC1
... Purpose: Thyroid cancer is the most common malignancy in Korean females and can be treated with good ...of thyroid cancer such as poorly differentiated or anaplastic thyroid ...
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PI3K/Akt/mTOR and CDK4 combined inhibition enhanced apoptosis of thyroid cancer cell lines
... in thyroid cancers is PI3K signaling cascade(Vasko et ...induce cell growth (Ansari et ...in thyroid cancer (Maleki et ...of cancer progression, which is closely related to cell ...
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The effect of antagonizing RGD-binding integrin activity in papillary thyroid cancer cell lines
... PTC cell lines we investigated, TPC1 showed a significant loss of cell viability while BCPAP and K1 cells exhibited a mild reduction in cell proliferation after detachment from the flask ...
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Original Article High expression of HAX-1 protein is associated with tumor growth in papillary thyroid carcinoma
... Abstract: Papillary thyroid carcinoma (PTC) is the most common type of endocrine malignancy. HS1-associated pro- tein X-1 (HAX-1) is an anti-apoptotic factor involved in the development of many types of ...
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CD133 as a Biomarker of Thyroid Cancer Stem Cells
... anaplastic thyroid cancer ...normal thyroid cells and cannot form the ...serum thyroid-stimulating hormone level and all presently valid treatment modalities (Bozorg-Ghalati and Hedayati, ...
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Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin
... human thyroid cancer cells, we measured expression of glucose transporter (GLUT1, GLUT2, GLUT5) genes and the hexokinase 1 gene in a panel of cell ...papillary thyroid cancer (BHP18-21) ...
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Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells
... human thyroid cancer cell lines was dose-dependent with an over-proportional increase between 1 and 10 M ellipticine, and influenced by the cell culture conditions (Table 1, ...in ...
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RCAN1-4 is a thyroid cancer growth and metastasis suppressor
... different thyroid cancer cell lines, FTC236 and HTh74 cells, with different genetic ...ATC cell line characterized by TP53 mutation (33, ...3D cell culture has more ...
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Original Article SASH1 inhibits proliferation and invasion of thyroid cancer cells through PI3K/Akt signaling pathway
... osteosarcoma cell viability, proliferation, and invasive ability ...lung cancer cell growth and proliferation as well as promote cellular apoptosis ...mary thyroid cancers [5]. However, the ...
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Centrosomal and mitotic abnormalities in cell lines derived from papillary thyroid cancer harboring specific gene alterations
... Cells for immunofluorescence were cultured directly on flaskette glass slides (NUNC A/S, Roskilde, Denmark). The cells were fixed with methanol:acetone (1:1) for 10 min at -20°C, followed by 10 min methanol at -20°C. ...
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Obatoclax kills anaplastic thyroid cancer cells by inducing lysosome neutralization and necrosis
... target thyroid cancer cells, inducing cell death with mixed apoptotic, necrotic, and autophagic features ...ovarian cancer cells, leading to their alkalization [50], providing an independent ...
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Original Article Wnt5a involved in regulation of the biological behavior of hepatocellular carcinoma
... breast cancer cell lines MDA-MB-231 and 4T1 and FTC-133 cells, a thyroid cancer cell line, resulting in decreased invasion, migration, clonogenicity and proliferation [9, ...
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miR-195 is a key regulator of Raf1 in thyroid cancer
... in thyroid cancer, protein and mRNA levels of Raf1 are checked in B-CPAP and ACT-1 overexpressing stable cell ...in thyroid cancer cells, and miR-195 can regulate the expression of Raf1 ...
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<p><em>Long noncoding RNA H19</em> is a critical oncogenic driver and contributes to epithelial-mesenchymal transition in papillary thyroid carcinoma</p>
... multiple cancer types and its elevated expression was tightly linked to tumorigenesis and cancer ...in cancer than normal samples across a wide variety of datasets in different cancer ...in ...
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IGFBP7 inhibits cell proliferation by suppressing AKT activity and cell cycle progression in thyroid carcinoma
... FRO cell lines were synchronized by serum starvation for 36 h and then induced to re-enter the cell cycle by the addition of 10% ...FTC cell lines increased the percentage of cells in ...
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Molecular profiling of thyroid cancer subtypes using large-scale text mining
... between cancer and its molecular bases from the ...prostate cancer and genes ...to cancer related studies as well, including FACTA [24], CoPub [25], DigSee [26] and OncoSearch (http://onco- ...and ...
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Dioscin inhibits gastric tumor growth through regulating the expression level of lncRNA HOTAIR
... gastric cell line MGC-803 and the concentration of dioscin at 56 μmol (Half Maximal Inhibitory Concentration) for further stud- ...gastric cancer, siRNA was used to silence HOTAIR expression, and we also ...
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Long non coding RNA expression profile in human gastric cancer and its clinical significances
... Gastric cancer-associated transcript 1; H19: The reciprocally imprinted partner of Igf2; HCC: Hepatocellular carcinomas; HOTAIR: HOX transcript antisense RNA; HOX: Homeobox; HULC: Highly upregulated in liver ...
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The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model
... Nicklin et al. have well studied the relationship be- tween LAT1-dependent leucine uptake and mTOR [3]. Here, we used Phospho-S6 and Phospho-p70S6K as readouts for mTORC1 activity and found a decrease of Phospho-S6 and ...
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