Tissue specific gene
Promise of BLCA38 as a Targeting Antibody for Tissue-Specific Gene Delivery to Prostate Cancer
... prostate specific membrane antigen), were used to target gene delivery to PC cells by conjugation with a transductionally modified gene transfer vector, Ad5/GFP-C2C2, expressing the reporter ...
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GeneTIER: prioritization of candidate disease genes using tissue-specific gene expression profiles.
... candidate gene is not feasible, a method is needed to decide which genes are worth investigating ...Computational gene prioritization presents itself as a solution to this problem, systematically analyzing ...
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The sulfate transporter family in wheat: tissue-specific gene expression in relation to nutrition
... of tissue specific- ity, variation in development or nutritional status dependent upon any of these factors in combination with environmental ...a tissue-specific ...a tissue or ...
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Tissue-Specific Gene Inactivation in Xenopus laevis: Knockout of lhx1 in the Kidney with CRISPR/Cas9
... We thank the instructors and teaching assistants of the 2015 and 2016 Cold Spring Harbor Laboratory Xenopus Course, in particular K.J. Liu, M.K. Khokha, and E.K. Mis, for training in Xenopus CRISPR gene editing ...
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The Relation of Codon Bias to Tissue-Specific Gene Expression in Arabidopsis thaliana
... a tissue could differ some- what in their codon ...of gene expression during Arabidopsis development have revealed that, despite the large overlap in expressed genes, organ systems have distinct tran- ...
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Sn, a light-dependent and tissue-specific gene of maize: the genetic basis of its instability.
... It might well be that DNA modification could account for this instability since the frequent changes Sn:bol3 undergoes from strong to weak variants, gen- erally a unidi[r] ...
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Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice
... this specific timepoint at the AIP, pancreatic specification is considered to be the default pathway of the endoderm, whereas cells of the definitive endoderm in contact with FGF signals released from cardiac ...
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A tissue-specific gene expression template portrays heart development and pathology
... a gene expression template (GET) containing only 56 genes could be used as a molecular signature to accurately specify at least 24 different disease-free tissues [12], including the ...maintaining specific ...
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Tissue specific and ubiquitous gene knockouts by TALEN electroporation provide new approaches to investigating gene function in Ciona
... for gene knockout does not exist in this organism and most data on gene function are based on knockdowns by morpholino antisense ...of gene targeting in Ciona by microinjecting ZFN mRNA to reliably ...
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An advanced reference genome of Trifolium subterraneum L. reveals genes related to agronomic performance
... confirmed gene expression for response to water deprivation, flavonoid biosynthesis and embryo development ending in seed dormancy, reflecting adaptation to the harsh Mediterranean ...of ...
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Identification of the minimal melanocyte-specific promoter in the melanocortin receptor 1 gene
... MC1R gene might be achieved not only by the positive activity of tissue-specific transcription fac- tors, such as MITF [12], expressed in the pigmented cells but also through DNA-protein complexes ...
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Differential expression of Lp PLA2 in obesity, type 2 diabetes and the influence of lipids
... adipose tissue biop- sies from participants who were lean (age ...adipose tissue was homogenised in Phosphosafe extraction buffer (Novagen, Merck, Darmstadt, Germany) and cultured adipocytes were har- ...
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ApoE knockout mice expressing human matrix metalloproteinase 1 in macrophages have less advanced atherosclerosis
... MMP-1 gene, and non- transgenic apoE0 littermates were used as the control ...the specific degradation product of collagenase-cleaved type I collagen, using the biotiny- lated monoclonal antibody 9A4 ...
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Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types
... unlike gene expression, we have little understanding of the contexts in which PPIs take ...work specific to the context of the disease being ...use gene expression data to mod- ify generic PPI ...
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Tissue specific regulation of CYP2B gene expression
... CYP2B gene expression is subject to tissue-specific ...the tissue specific expression of CYP2B genes was studied using both western blot and RNase protection ...this tissue into ...
202
Tissue-Specific, Tumor-Selective, Replication-Competent Adenovirus Vector for Cancer Gene Therapy
... a specific receptor on cells (1, 58), and targeting transcription such that vector replication and/or transgene expression will occur only in ...and tissue- specific promoters ...the tissue- ...
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Pathogenesis and Host Response During Infection of Maize Kernels by Aspergillus flavus and Fusarium verticillioides.
... 147 UDP-glucose (Xu et al., 1989). Upregulation of Sh1 was also observed in maize leaves upon U. maydis infection, whereas sucrose contents were slightly increased in this interaction (Doehlemann et al., 2008). This ...
263
Effects of DACT1 methylation status on invasion and metastasis of nasopharyngeal carcinoma
... After the cells were harvested, the total DNA of each group of cells was extracted using a DNA extraction kit. Then, the bisulfite modification was carried out using a DNA methylation kit. According to the DACT1 ...
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Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease
... adipose tissue NAFLD networks and sex hor- mone target ...corresponding tissue and sex (Table 1, ...liver gene expression, suggesting minor contribution of estro- gen deficiency to the ...
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Tissue and development specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase
... nNOS gene designated nNOSa, nNOSb, and nNOSc, respectively, with distinct 5 9 untranslated first exons that arise from alternative splicing to a common sec- ond ...of tissue and developmental specificity, ...
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