tissue specificity in gene expression
Nutritional regulation and tissue specificity of gene expression for proteins involved in hepatic glucose metabolism in rainbow trout (Oncorhynchus mykiss)
... 5. Tissue specificity of 6-phosphofructo-2-kinase/ fructose-2,6-biphosphatase (6PF-2K/F-2,6BPase), pyruvate kinase (PK), fructose-1,6-bisphosphatase (FBPase) and glucose transporter type 2 (Glut2) ...
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A comprehensive functional analysis of tissue specificity of human gene expression
... generated tissue-specific networks for nine tissues using the Analyze Networks (AN) network algorithm in ...The tissue- specific networks for liver and adrenal gland are shown in Figure ...on gene ...
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Organ specific gene expression: the bHLH protein Sage provides tissue specificity to Drosophila FoxA
... activate expression of CrebA, Sage, Fkh and Hkb, which function to maintain and implement the SG fate decision by maintaining their own expression, the expression of each other and of terminally ...
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Too much data, but little inter-changeability: a lesson learned from mining public data on tissue specificity of gene expression
... in tissue expression patterns between SAGE and Affyme- trix platforms for most of 33 loci in Additional file 1 can be explained by one of 3 factors: (1) Prior to statistical analysis of the data, SAGE tags ...
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Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor alpha, and transforming growth factor beta
... (PAI-1) gene expression was studied in vivo employing a murine model ...adipose tissue, heart, and lungs of untreated CB6 (BalbC X C57B16) ...adipose tissue and the kidney, while LPS and ...
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Translational contributions to tissue specificity in rhythmic and constitutive gene expression
... of tissue- specific mRNA variants generated by alternative tran- scriptional start sites, splicing and 3′ processing—had any relationship to differential ...relative expression levels per gene and ...
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Regulation of gene expression by Pax6 in ocular cells: a case of tissue preferred expression of crystallins in lens
... crystallin gene regulation (see Duncan et ...Pax gene, regulates expression of invertebrate J3- crystallin promoter (Kozmik et ...the expression of the endogenous gene at a level ...
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The cell specificity of gene expression in the response to heat stress in corals
... the expression patterns of specific gene networks after heat stress show strong correlations with variation in bleaching ...spatial gene expression of genes previously predicted to be involved ...
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Probing for gene specificity in epithelial development
... most gene products would be expressed in a variety of tissues and cell types in Drosophila and that patterns of gene expression may be complex and overlapping even within ...cause expression ...
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Tumour-specific triple-regulated oncolytic herpes virus to target glioma
... HSV-1 gene ICP4 was replaced with a tumour specific survivin ...ICP4 gene open reading frame. Our results confirmed enhanced expression of survivin and eIF4E in different glioma cells and increased ...
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Tissue specific regulation of CYP2B gene expression
... promoter regions. CYP2B1 and CYP2B2 5' flanking sequences differ with respect to a CA repeat {CYP2B2 CA=19 and CYP2B1 CA=5). The other two bands of 610 and 340 base pairs, however, were not expected and could represent ...
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Differential expression of Lp PLA2 in obesity, type 2 diabetes and the influence of lipids
... Results Lp-PLA2 and calcium-independent PLA2 (iPLA2) isoforms were altered by adiposity, as shown by microarray analysis (p < 0.05). Type 2 diabetes status was also observed to significantly alter gene and ...
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Reduced fructosamine-3-kinase activity and its mRNA in human distal colorectal carcinoma
... Fructosamine-3-Kinase (FN3K) enzymatic activity was measured in normal colorectal mucosa and cancer. The tissue samples were left in 500 ll of homogenization buffer 10 mM Tris–HCl (pH 7.8), 1 mM DTT, 1 lg/ml ...
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CART cell therapy for prostate cancer: status and promise
... Abstract: In recent years, the, chimeric antigen receptor T (CAR-T) cell therapy as an adoptive immunotherapy has received great attention and made great breakthroughs. CAR-T cells show great specificity, ...
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The False Paradigm of RUNX3 Function as Tumor Suppressor in Gastric Cancer
... RUNX gene family. RUNX TFs are key gene expression regulators in several important developmental processes including hemato- poiesis, osteogenesis and neurogenesis ...[14,15]. Tissue-specific ...
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Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes
... NUP62 gene has a CpG island and is ubiquitously ...of gene regu- ...specific expression of two genes from one promoter is novel, espe- cially when the transcripts contain exons from both ...far, ...
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Next generation sequencing based expression profiling identifies signatures from benign stromal proliferations that define stromal components of breast cancer
... coordinated gene expression with consistent association with outcome in all the four breast cancer ...core gene sets, while 44 to 47% of breast cancers were negative for both, 23 to 33% of breast ...
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2017_Zattra.pdf.pdf
... Obesity is among the most prevalent conditions worldwide: in the United States alone, more than 60% of the population is either overweight or obese. The condition remains a well-known modifiable risk factor for multiple ...
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Qualitative transcriptional signatures for evaluating the maturity degree of pluripotent stem cell-derived cardiomyocytes
... the gene expression profiles of normal adult cardiac tissue and embryonic stem cell (ESC) samples, we identified gene pairs with identically relative expression orderings (REOs) within ...
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Type-C RNA Virus Gene Expression in Human Tissue
... The 1251labeled antigens used in the competition radioimmunoassay to measure viral proteins in human cells were the major structural core proteins of type-C viruses, the p30 of Rauscher [r] ...
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