TM-domain
Specialised information processing deficits and distinct metabolomic profiles following TM-domain disruption of Nrg1
... Although there is considerable genetic and pathologic evidence for an association between neuregulin 1 (NRG1) dysregulation and schizophrenia, the underlying molecu- lar and cellular mechanisms remain unclear. Mutant ...
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Functional Analysis of the Transmembrane (TM) Domain of the Autographa californica Multicapsid Nucleopolyhedrovirus GP64 Protein: Substitution of Heterologous TM Domains
... the TM domain of the influenza virus hemagglutinin (HA) protein with a glycosylphosphatidylinositol (GPI) anchor resulted in a protein that mediated hemifusion (17) and fusion pore formation, but an ...
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Specialised information processing deficits and distinct metabolomics profiles following TM domain disruption of Nrg1
... Specifically, activation in the cingulate gyrus, left middle frontal gyrus, bilateral fusiform gyrus, and left middle occipital gyrus was modulated by NRG1 genotype during the encoding phase of the task. During the ...
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TM domain swapping of murine leukemia virus and human T-cell leukemia virus envelopes confers different infectious abilities despite similar incorporation into virions.
... anti-MuLV TM p15E serum and goat anti-MuLV SU gp70 ...and TM components are indicated at the bottom, with the TM comprising the external (TMe) and intracellular (TMi) ...TMi domain is further ...
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A Transmembrane Domain and GxxxG Motifs within L2 Are Essential for Papillomavirus Infection
... (TM) domain prediction algorithms. Here, we describe a conserved TM domain within L2 (residues 45 to 67) and investigate its role in HPV16 ...predicted TM domain adopts an ...
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Expression and purification of the p75 neurotrophin receptor transmembrane domain using a ketosteroid isomerase tag
... NTR TM domain could be purified using this procedure with more than 90% purity from SDS-PAGE ...NTR TM domain were verified by mass spectrometry (Figure ...NTR TM domain, the ...
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Influenza A virus M2 ion channel protein: a structure-function analysis.
... To begin a structure function analysis of the residues in the human influenza virus A/Udorn/72 M, protein TM domain, the pH activation response of the amantadine-resistant mutants V27A, [r] ...
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Mutational analysis of the beta-type platelet-derived growth factor receptor defines the site of interaction with the bovine papillomavirus type 1 E5 transforming protein.
... ectodomains, TM domains, and cytoplasmic domains of the a and b ...PDGFR TM domain and juxtamembrane residues were required for E5 binding, receptor activation, and induction of IL-3-indepen- dent ...
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Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility
... a TM domain of hu-tetherin displayed BiFC signals compara- ...tetherin TM with ...the TM, ECL, CC, or GPI between the hu- and mo-tetherin proteins and analyzed by flow ...Vpu TM with ...
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The Transmembrane Domain Sequence Affects the Structure and Function of the Newcastle Disease Virus Fusion Protein
... the TM do- main significantly increased the signal obtained with anti-Fu1a, indicating that the binding site for this antibody was affected by changes in the TM domain sequence of the protein and ...
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The Autographa californica Multicapsid Nucleopolyhedrovirus GP64 Protein: Analysis of Transmembrane Domain Length and Sequence Requirements
... truncated TM domain to span the bilayer membrane and promote membrane fusion ...truncated TM domains were synthesized and oligomerized in transfected cells ...the TM domain revealed no ...
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Investigation and characterisation of transmembrane domain interactions in Carnitine Palmitoyltransferase 1 Isoforms
... Before this work to express the CPT1A and CPT1B TM domains as peptides in E. coli, the expression of full length CPT1 was attempted in the yeast P. pastoris. Previous attempts to express full length CPT1 in E. ...
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Non-canonical Wnt signaling via the Ryk and Ror receptors in the drosophila nervous system
... intracellular domain (indicated by an asterisk), evident in the anti-MYC blots, increase in intensity during the immunoprecipitation, presumably due to the presence of proteases resistant to the inhibitors ...the ...
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Functional interactions between monomers of the retroviral envelope protein complex.
... full-length TM mu- tants and that there was a degree of heterogeneity in the extent of the syncytia that ...the TM mutants (which provided the functional SU subunit) were able to bind to the MoMuLV receptor ...
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An NMR study into the structure and interactions of the transmembrane domains of Neu and PDGFβ receptor tyrosine kinases
... techniques, including X-ray crystallography and solution-state NMR spectroscopy. Their significance in the latter is underscored by the fact that a large majority of membrane protein structures obtained to date have been ...
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Biofunctional Nb/Ti-MCM-41 catalyst in oxidative acidic reaction of cyclohexene to diol
... Surface acidity of the samples was carried by pyridine adsorption at room temperature on the dehydrated samples at 400 o C under vacuum and monitored by IR spectroscopy. The type and the amount of the acid sites can be ...
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Frauenfeld, Jens (2010): The ribosome-SecYEG complex in the membrane environment. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... representing TM helices 6,8,9. Minor adjustments of the TM helices were carried out using Coot (Emsley and Cowtan, ...N-terminal TM helices of SecE were placed into two additional rod-like densities, ...
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Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma.
... Notch2 TM and intracellular domain (MET- 79) as the initiation codon for truncated Notch2 protein de- spite the fact that it is located downstream of MET-env: (i) the construct D env-FeLV/N2-B-myc, which ...
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The Definitive Guide To tm The Definitive Guide To tm
... You have seen how to enable the Terminal Services Role, set up a Session Directory, assign applications to your servers through Group Policy, and configure the Automatic Updates client[r] ...
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Characterizing a Biomedical Hydrogel Device
... Dextran plays an active role in the pharmaceutical industry. Specifically, unmodified dextran, with a molecular weight ranging from 75,000 ± 25,000, is used as a blood plasma substitute, as 6% solutions have a viscosity ...
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