transient receptor potential vanilloid type
Implication of AMP-Activated Protein Kinase in Transient Receptor Potential Vanilloid Type 1-Mediated Activation of Endothelial Nitric Oxide Synthase
... in transient receptor potential vanilloid type 1 (TRPV1)-mediated activation of endothelial nitric oxide synthase (eNOS) in en- dothelial cells (ECs) and ...
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Capsazepine, a Transient Receptor Potential Vanilloid Type 1 (TRPV1) Antagonist, Attenuates Antinociceptive Effect of CB1 Receptor agonist, WIN55,212-2, in the Rat Nucleus Cuneiformis
... Cannabinoids have been shown to produce analgesia in neuroanatomical regions subserving transmission and modulation of pain signals, including the PAG, rostral ventrolateral medulla (RVM), basolateral nucleus of amygdala ...
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Post-transcriptional regulation of 5’-untranslated regions of human Transient Receptor Potential Vanilloid type-1 (TRPV-1) channels: role in the survival of glioma patients
... The Transient Receptor Potential Vanilloid type-1 (TRPV1) channel is a non- selective cation channel belonging to the Transient Receptor Potential family; variation ...
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Mother root of Aconitum carmichaelii Debeaux exerts antinociceptive effect in Complete Freund’s Adjuvant induced mice: roles of dynorphin/kappa opioid system and transient receptor potential vanilloid type 1 ion channel
... -opioid receptor contributes to its antinociceptive process, and it also suggested that other central mecha- nisms may not be involved in the antinociceptive effects of PCW under inflammatory ...
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Implication of Transient Receptor Potential Vanilloid Type 1 in 14,15-Epoxyeicosatrienoic Acid-induced Angiogenesis
... wild type (WT), TRPV1-Y671K or TRPV1-Y671D with the ...analysis. Transient transfection in- volved use of TurboFect according to the manufac- turer’s ...
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THE ROLE OF TRANSIENT RECEPTOR POTENTIAL VANILLOID 1 RECEPTOR IN DESIPRAMINE INDUCED ANALGESIC EFFECT IN DIABETIC MICE
... cord. Transient receptor potential vanilloid type 1 (TRPV1) present in spinal cord and activation of C-fibre may involve in hyperalgesia in diabetic ...
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Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies
... The aim of this chapter was to validate and optimise a Western blotting method to detect TRPV1 in leukocytes. The optimised method would later be used to detect TRPV1 protein in human PBMCs and haematological malignant ...
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Paeoniflorin protects diabetic mice against myocardial ischemic injury via the transient receptor potential vanilloid 1/calcitonin gene-related peptide pathway
... wild type mice; (2) PF-WTDM-L group: WTDM treated with 70 mg/kg of paeoniflorin; (3) PF-WTDM-H WTDM treated with 140 mg/kg of PF; (4) PF-WTDM-KN-93 group: KN-93 was used to treat DM mice; (5) TRPV1 −/− DM: TRPV1 ...
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Transient receptor potential (TRP) gene superfamily encoding cation channels
... In humans, 27 different TRP genes are grouped into six different subfamilies based on their amino acid homologies (Table 1). The nomenclature of the TRP superfamily has been evolving for many years. Many genes and ...
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Capsaicin in metabolic syndrome
... on transient receptor potential vanilloid channel 1 ...disease, type 2 diabetes, and non-alcoholic fatty liver ...proliferator-activated receptor α (PPARα), uncoupling protein 1 ...
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Expression of transient receptor potential vanilloid (TRPV) channels in different passages of articular chondrocytes
... of transient receptor potential vanilloid channel members 4, 5 and 6 (TRPV4, TRPV5 and TRPV6) in equine articular ...of type I collagen instead of type ...
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Lack of transient receptor potential vanilloid 1 channel modulates the development of neurogenic bladder dysfunction induced by cross-sensitization in afferent pathways
... either cyclophosphamide- or acrolein-induced models of bladder inflammation [46]. This group also established that abdominal hyper-reactivity and cutaneous allodynia were abolished in TRPV1 −/− mice. Likewise, selective ...
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Reduced transient receptor potential vanilloid 2 expression in alveolar macrophages causes COPD in mice through impaired phagocytic activity
... gen type IV and surfactant protein-A (SP-A), which pro- tect against development of COPD, are upregulated despite progression of destructive changes in the lung ...
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Interaction Between the Cannabinoid and Vanilloid Systems on Anxiety in Male Rats
... coupled receptor found in the mammalian brain (Matsuda, Lolait, Brownstein, Young, & Bonner, 1990) and are particularly abundant in the cortex, hippocampus, nucleus accumbens, and amygdala (Millan, ...
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Cloning of the Vanilloid-like Receptor VR-L and investigation of its interaction with members of the transient receptor potential family of receptors
... Calcium imaging and patch clamp studies of HEK293 cells expressing V Rl showed the receptor to respond to heat above a temperature threshold of 42^ C with currents similar [r] ...
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Transient Receptor Potential Vanilloid 1 Immunoreactive Innervation Increases in Fractured Rat Femur
... Fig. 4. Distribution and ratio of FG-labeled and TRPV1-ir DRG neurons innervating the left femur among control, 3 days, 1 week, 2 weeks, and 4 weeks groups. FG-labeled and TRPV1-ir DRG neurons innervating the left femur ...
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Forsythoside A exerts antipyretic effect on yeast-induced pyrexia mice via inhibiting transient receptor potential vanilloid 1 function
... Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel gated by noxious heat, playing major roles in thermoregulation. Forsythoside A (FT-A) is the most abundant ...
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Original Article Upregulation of the transient receptor potential vanilloid 1 in colonic epithelium of patients with active inflammatory bowel disease
... genesis of experimental colitis. The expression of TRPV1 in colonic epithelium and its correlation with inflammatory bowel disease (IBD) are poorly understood. In this study, colonic biopsies were taken from 60 patients ...
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Abundant expression and functional participation of TRPV1 at Zusanli acupoint (ST36) in mice: mechanosensitive TRPV1 as an “acupuncture responding channel”
... Capsaicin has been used in other experiments to study noxious stimulus-induced analgesia (NSIA) [62,63]. Cap- saicin stimulation releases glutamate and substance P at the spinal dorsal horn, activating NMDA, AMPA/kai- ...
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Mechanism and therapeutic effectiveness of nerve growth factor in osteoarthritis pain
... Abstract: Osteoarthritis (OA) is the most common form of articular joint arthritis and a cause of significant morbidity. In this review, we present the role of nerve growth factor (NGF) in pain generation, relationship ...
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