TSP, thrombospondin
Identification of thrombospondin 1 (TSP 1) as a novel mediator of cell injury in kidney ischemia
... identify TSP-1 as the molecule with the highest induction level at 3 hours of IR injury in rat and mouse kidneys subjected to ischemia/reperfusion (IR) inju- ry using the DNA microarray ...that TSP-1 ...
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Original Article Altered expression of thrombospondin-1/-2 in the cortex and synaptophysin in the hippocampus after middle cerebral artery occlusion and reperfusion
... peroxide (H 2 O 2 ) for 30 min. The sections were subjected to sequential incubations with 10% normal goat serum in 0.01 M PBS for 30 min at room temperature. Slices were then incubated in rabbit anti-TSP-1/-2 ...
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Role of thrombospondin in platelet aggregation
... microaggregates and nonaggregated single platelets. Anti-TSP Fab did not affect the initial phase of ADP-induced platelet aggregation but caused rapid platelet disaggregation with the abolition of the secondary ...
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Histidine rich glycoprotein inhibits the antiangiogenic effect of thrombospondin 1
... Angiogenesis, the development of new blood vessels, is necessary for a variety of normal physiologic processes as well as for the growth and proliferation of tumors. The identification of natural modulators of ...
9
Isolation of the thrombospondin membrane receptor
... for TSP. Endogenous platelet TSP binding to thrombin- and ionophore-stimulated human platelets was inhibited in the presence of the monoclonal antibody ...OKM5. TSP binding to C32 melanoma cells and ...
9
Disruption of the thrombospondin 2 gene alters the lamellar morphology but does not permit vascularization of the adult mouse lumbar disc
... There is a complex biological relationship between the intact disc matrix and cells and the nearby vasculature outside the disc. We have shown that although an increase in vasculature was present in the TSP-2-null ...
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Thrombospondin induced adhesion of human platelets
... on thrombospondin (TSP)- coated microtiter ...EDTA. TSP- dependent adhesion was inhibited by anti-TSP fab fragments, an anti-TSP monoclonal antibody, an RGD-containing peptide, ...
9
Thrombospondin 1 mediates oncogenic Ras–induced senescence in premalignant lung tumors
... that TSP-1 expression has a posi- tive correlation with survival of lung cancer patients ...of TSP-1 is a prom- ising prognostic factor for overall survival of patients with lung adenocarcinomas treated ...
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Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration
... cyclic thrombospondin- 1 (TSP-1) mimetics using disulfide-rich frameworks for anti-angiogenesis therapies and to determine whether these peptides have better potency than the linear parent ...from ...
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Platelet thrombospondin forms a trimolecular complex with plasminogen and histidine rich glycoprotein
... Thrombospondin (TSP), a multifunctional alpha-granule glycoprotein of human platelets binds fibrinogen, fibronectin, heparin, histidine-rich glycoprotein (HRGP), and plasminogen (Plg), and thus, may play an ...
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Antisense mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma
... transfected antisense sequence in these clones was verified by a ribonuclease protection assay. These clones demonstrated reduced growth rates in vitro when compared with a vector transfected control. After subcutaneous ...
7
Thrombospondin induced adhesion of human keratinocytes
... on thrombospondin (TSP)-coated plastic dishes but failed to attach and spread on untreated plastic culture dishes or dishes coated with fibronectin or ...on TSP-coated dishes. These cells also ...
9
An ACO Approach to Solve a Variant of TSP
... the TSP data sets are created by randomly generating city coordinates in the range 0 to ...the TSP: pheromone trails are associated with the arcs (edges), and heuristic values are given by the inverse of ...
5
Identification and characterization of six novel tetraspanins from Schistosoma japonicum
... Sj- TSP-#6 ...that TSP members likely have different functions during various development stage of ...the TSP proteins of the para- site can be expressed either tegument component or the ...
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A HEURISTIC ALGORITHM FOR TSP OF COMPLETE GRAPH
... Step 13: From lower to higher one after another edge is considered from the ordered list-8, obtained at step 12 and it is tested whether this edge connection to the list-7 will make [r] ...
7
ACO Parameters Analysis of TSP Problem
... Abstract- A recently proposed algorithm named Ant colony optimization algorithm (ACO) is simple to merge with additional methods. The application of Ant Colony Optimization is much wider and it is always the key ...
6
Identification of a new class of inducible receptors on platelets Thrombospondin interacts with platelets via a GPIIb IIIa independent mechanism
... of thrombospondin with platelets. Radioiodinated thrombospondin bound to thrombin-stimulated platelets from normal and thrombasthenic donors with ...
5
Complex formation of platelet thrombospondin with fibrinogen
... platelet thrombospondin. The formation of the fibrinogen-thrombospondin complex was specific, saturable, and partially inhibited by mannosamine, glucosamine, and ...platelet thrombospondin lectin ...
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A Bacteriophage of Bacillus subtilis Which Forms Plaques Only at Temperatures Above 50 C II. Reduction of TSP-1-Specific Receptor Sites on Cells Grown at 37 C or 45 C, and the Temperature-Dependent Inactivation of Replicating Phage
... If TSP-1 did not adsorb due to the absence of phage receptor sites, it should be rapidly neutralized by TSP-1 antiserum, and the culture would be protected from infection.. These results[r] ...
7
Beads: Journal of the Society of Bead Researchers - Volume 3 (complete)
... Circular; tsl. oyster white with tsp. dark shadow blue with tsp. dark navy exterior and core; op. white middle layer; 12.. op. white stripes.[r] ...
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