Tubulin genes
Spatial expression of alpha and beta tubulin genes in the late embryogenesis of the sea urchin Paracentrotus lividus
... Int I Dc\" lliol 40 1033 1041 (1996) 1033 Original Article Spatial expression of exand B tubulin genes in the late embryogenesis of the sea urchin Paracentrotus lividus CATERINA CASANO MARIA RAGUSA MA[.] ...
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Isolation and characterization of cDNA clones for beta tubulin genes as a molecular marker for neural cell differentiation in the ascidian embryo
... Int J Dc, lIiol 41 551 557 (19971 551 Origilllli Arlie/I' Isolation and characterization of cDNA clones for ~ tubulin genes as a molecular marker for neural cell differentiation in the ascidian embryo[.] ...
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Mutations in tubulin genes are frequent causes of various foetal malformations of cortical development including microlissencephaly
... different tubulin genes ( TUBA1A, TUBB2B and TUBB3 ), underlining the relatively high frequency of tubulinopathies among the causes of severe complex cortical malformations ranging from polymicro- ...
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GENETIC ANALYSIS OF RESISTANCE TO BENZIMIDAZOLES IN PHYSARUM: DIFFERENTIAL EXPRESSION OF β-TUBULIN GENES
... This paper reports (1) isolation and genetic analysis of mutants of Physarum obtained by selecting for myxamoebal resistance to MBC, (2) analysis of the tubulins of MBC-[r] ...
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Unlinked noncomplementation: isolation of new conditional-lethal mutations in each of the tubulin genes of Saccharomyces cerevisiae.
... We have demon- strated that strains bearing mutations in unlinked genes that encode interacting proteins may fail to complement, and we have used this property o[r] ...
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Genetic variability of the beta-tubulin genes in benzimidazole-susceptible and -resistant strains of Haemonchus contortus.
... Comparison of susceptible to resistant strains: The number of alleles observed in the susceptible strain was higher at both loci than in the resistant strains and allele freq[r] ...
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Interacting genes that affect microtubule function in Drosophila melanogaster: two classes of mutation revert the failure to complement between haync2 and mutations in tubulin genes.
... T h e recessive male sterile mutation haync2 of Drosophila melanogaster fails to complement certain &- tubulin and a-tubulin mutations, suggesting that the haywire [r] ...
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Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS
... four tubulin genes and the phenotype was suppressed by tub2-423 and Dtub3 mutations, establishing a genetic link between H3K4 methylation and microtubule ...
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Genetic interactions at the FLA10 locus: suppressors and synthetic phenotypes that affect the cell cycle and flagellar function in Chlamydomonas reinhardtii.
... Although the tubulin genes would be likely targets for mutations that confer resistance to these compounds, genetic mapping and restriction frag- ment length polymorphism[r] ...
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Archaeal origin of tubulin
... the tubulin/FtsZ superfam- ily (see Additional File 2) was employed to build maxi- mum likelihood phylogenetic trees using FtsZ proteins as the ...bacterial tubulin sequences grouped within the eukaryo- tic ...
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An α-Tubulin Mutant Demonstrates Distinguishable Functions Among the Spindle Assembly Checkpoint Genes in Saccharomyces cerevisiae
... meiosis causes aneuploidy, which can lead to deleterious When shifted to the nonpermissive temperature (15⬚), consequences such as cancer and birth defects. Microtu- cells expressing tub1-729, a class 1 allele, as its ...
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4. B.Kadalmani, M.Mahalakshmi, and R.R.Dinesh Kumar
... the tubulin, which is a globular ...important genes for the mitosis and sperm ...to tubulin and totally disrupting the microtubule formation and ...
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The role of tubulin tubulin lattice contacts in the mechanism of microtubule dynamic instability
... RESULTS Determination of 13-PF structures of DCX-MTs in different nucleotide states To elucidate the mechanism of MT catastrophe, we analysed conformational changes in tubulin through it[r] ...
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Antimitotic herbicides bind to an unidentifed site on malarial parasite tubulin and block development of liver stage Plasmodium parasites
... Protein affinity assay using the tubulin fusion proteins.. The affinity of the tubulin fusions for other proteins was determined by their ability to.[r] ...
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LMO4 functions as a co activator of neurogenin 2 in the developing cortex
... NGN2-target genes, b-III tubulin, FoxP1 and Tbr1 is substantially reduced, suggesting that LMO4 plays an important role in cortical neuronal differentiation at least partly by supporting NGN2-mediated gene ...
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Validation of reference genes for expression analysis in the salivary gland and the intestine of Rhodnius prolixus (Hemiptera, Reduviidae) under different experimental conditions by quantitative real time PCR
... Understanding the patterns of gene expression is important to provide insights into complex regulatory networks and will lead to the identification of genes rele- vant to new biological processes [13]. However, ...
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An Innovation in the Cancer Therapy by the Interaction of Docetaxel to the Demethylpodophyllotoxin site of Tubulin
... . Tubulin was polymerized to form microtubules at body temperature for 30 ...Further tubulin purification was obtained by repeated polymerization and depolymerisation in the absence of glycerol with ...
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Function of Tubulin Binding Proteins in Vivo
... YCpGAL control plasmid were ob- tained after 4 hr of growth in induc- ing media. The whole cell extract (WCE) was probed directly for the tubulin polypeptides and Cin1p, or applied to Ni-NTA columns (see ma- ...
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Herpes Simplex Virus Type 1 Tegument Protein VP22 Induces the Stabilization and Hyperacetylation of Microtubules
... To confirm that the apparent VP22–a-tubulin colocalization represented an interaction between the two proteins, we used two drugs which are known to affect the stability of the MT network. First, both ...
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Different Functionals Domain of SpastinM87V Affect Cellular Microtubule Cutting
... of tubulin with positively charged AAA ATP ring holes, destroy the palisade structure of microtubules and cuase long microtubules to bend and break into small segments of microtubules [3, ...
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