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Tumour tissue

Assessing the Concordance of Genomic Alterations between Circulating-Free DNA and Tumour Tissue in Cancer Patients

Assessing the Concordance of Genomic Alterations between Circulating-Free DNA and Tumour Tissue in Cancer Patients

... the tumour and suppressing cell turnover, this could potentially affect the representation of clones in the cfDNA ...in tumour tissue in all cases ...

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Heterogeneity of microsphere distribution in resected liver and tumour tissue following selective intrahepatic radiotherapy

Heterogeneity of microsphere distribution in resected liver and tumour tissue following selective intrahepatic radiotherapy

... parenchyma, tumour tissue architecture is unstructured, with scattered fibrotic and necrotic areas that obviously influence the statistical re- ...for tumour tissue are included only to ...

9

Visualisation of HER2 homodimers in single cells from HER2 overexpressing primary formalin fixed paraffin embedded tumour tissue

Visualisation of HER2 homodimers in single cells from HER2 overexpressing primary formalin fixed paraffin embedded tumour tissue

... thick tissue sections were pre- pared from FFPE blocks of HER2 positive and nega- tive cancer samples (see Additional file 1 Figure ...the tissue sections were examined with LM, using fluor- escence ...

12

A gene expression profile for detection of sufficient tumour cells in breast tumour tissue: microarray diagnosis eligibility

A gene expression profile for detection of sufficient tumour cells in breast tumour tissue: microarray diagnosis eligibility

... the tumour sample con- tains sufficient tumour cells for ...of tumour cells to define the suitability of the ...sufficient tumour tissue will shorten the processing time for microarray ...

8

Image classification-based brain tumour tissue segmentation

Image classification-based brain tumour tissue segmentation

... Brain tumour tissue segmentation is essential for clinical decision ...brain tumour tissue segmentation is proposed using combined CNN- based and hand-crafted ...

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Methodology and analysis for the recognition of tumour tissue based on FDG PET

Methodology and analysis for the recognition of tumour tissue based on FDG PET

... of tumour tissue and its severity ...and tissue. For investigat- ing suspicious tissue a radioactive substance combined with an amount of fluorine-atoms is used, this substance ...

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Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients

Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients

... frozen tumour and respective normal lung tissue from asbestos- exposed and non-exposed lung cancer ...frozen tissue samples using NE- PER extraction kit according to the protocol provided (Pierce, ...

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Quantification of fluorescence signals from 800CW labelled tumour tissue

Quantification of fluorescence signals from 800CW labelled tumour tissue

... non-tumorous tissue is crucial in fluorescence ...In tissue, and specifically in the NIR region, light scattering is the dominant process of the ...of tumour margins in surgical ...in tumour ...

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Tumour Tissue Microenvironment Can Inhibit Dendritic Cell Maturation in Colorectal Cancer

Tumour Tissue Microenvironment Can Inhibit Dendritic Cell Maturation in Colorectal Cancer

... prime tumour specific CD8 + T cells ...of tumour infiltrating DCs. [1]. One of these ‘pro-tumour’ factors, Vascular Endothelial Growth Factor (VEGF) is known for sustaining tumour growth via ...

9

Drug metabolism related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue

Drug metabolism related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue

... of tumour cells to anticancer ...and tumour tissue; in many cases, expression is altered in the tumour specimens as compared to normal breast ...

10

In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model

In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model

... the tumour at baseline conditions showed a peak at 5–10 min after injection ...lower tumour activity levels, but rather resulted in a counterintuitive significant increase in tumour activity, as well ...

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Monte Carlo modelling of photodynamic therapy treatments comparing clustered three dimensional tumour structures with homogeneous tissue structures

Monte Carlo modelling of photodynamic therapy treatments comparing clustered three dimensional tumour structures with homogeneous tissue structures

... that tumour tissue does not have a uniform ...the tumour was introduced by adopting 3D fractal clustered ...the tumour into clusters in a fractal manner, a 3D structure was ...the ...

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Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

... through tumour complexity at a cellular level, allowing the observer to score regions of tumour in more than one core that has a high concentration of cells with copy number ...macro-dissected tumour ...

10

The hypoxic tumour microenvironment

The hypoxic tumour microenvironment

... point, tumour growth decelerates, and HIF1 pro- motes the secretion of factors inducing vascularisation from tumour and stromal cells; for example, VEGF influences endothelial cells, pericytes and BMDC to ...

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Simultaneous automatic scoring and co registration of hormone receptors in tumour areas in whole slide images of breast cancer tissue slides

Simultaneous automatic scoring and co registration of hormone receptors in tumour areas in whole slide images of breast cancer tissue slides

... to tumour was successful in avoiding false positive ...the tumour area to be scored as a region of interest in order to distinguish invasive carcinoma from in-situ ...the tumour selected may, for a ...

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The Molecular Genetics of Wilms Tumour And The Wilms Tumour Predisposition Syndromes

The Molecular Genetics of Wilms Tumour And The Wilms Tumour Predisposition Syndromes

... Cell cycle replication time is one of the param eters th at has been show n to be associated w ith tissue-specific gene expression (Holm quist, 1987). The relative order of replication of hom ologous alleles an d ...

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Tissue factor, angiogenesis and tumour progression

Tissue factor, angiogenesis and tumour progression

... example, tissue factor pathway inhibitor) [86], inducing selective intratumoral thrombosis (tumour infarction) [87] or inducing immune attack [88] are currently being ...

10

HLA dependent tumour development: a role for tumour associate macrophages?

HLA dependent tumour development: a role for tumour associate macrophages?

... or tumour cells and tumour rejection in a multiple myeloma xenograft ...from tumour cell culture in response to non-lethal heat shock) act in a suppressive manner inhibiting NK cell- dependent ...

15

Characterisation of circulating tumour cells in men with advanced prostate cancer and correlation with numbers of circulating and tissue based inflammatory cells

Characterisation of circulating tumour cells in men with advanced prostate cancer and correlation with numbers of circulating and tissue based inflammatory cells

... Thanks also to Lauren Brady, who did most of the filtering and staining of the Dublin ScreenCell® filters on-site in St James’s, and was endlessly patient when her own work was delayed by my tardiness in producing ...

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Adrenomedullin and tumour microenvironment

Adrenomedullin and tumour microenvironment

... in tumour progression is becoming more relevant with recent ...the tumour cells but also by numerous stromal cells including macrophages, mast cells, endothelial cells, and vascular smooth muscle ...the ...

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