type-specific manner
Either ZEB1 or ZEB2/SIP1 Can Play a Central Role in Regulating the Epstein-Barr Virus Latent-Lytic Switch in a Cell-Type-Specific Manner
... Extracts of these same cell lines were examined likewise for their levels of the EBV-encoded immediate-early (IE) BZLF1 and early (E) BMRF1 lytic-gene products (Fig. 3A and B; Fig. 4), expression that is indicative of ...
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Gamma Interferon Blocks Gammaherpesvirus Reactivation from Latency in a Cell Type-Specific Manner
... cell type-specific ...these specific cells in vivo and in vitro after establishing ...cell type specific and raise the possibility that cell type-specific immune ...
7
The MAT1 Locus of Histoplasma capsulatum Is Responsive in a Mating Type-Specific Manner
... regulated manner, implying that the inability of laboratory strains to mate is not due to the loss of the ability to produce ...mating type in this ...
6
Activation of Innate Defense against a Paramyxovirus Is Mediated by RIG-I and TLR7 and TLR8 in a Cell-Type-Specific Manner
... Recognition of pathogens by the innate immune system is mediated by pattern recognition receptors (PRRs), which recognize specific molecular structures of the infectious agents and subsequently trigger expression ...
8
A Mutation in the Ebola Virus Envelope Glycoprotein Restricts Viral Entry in a Host Species- and Cell-Type-Specific Manner
... GP-NPC1 binding ELISA. GP-NPC1 enzyme-linked immunosorbent assays (ELISAs) were performed essentially as described previously (40). Briefly, high-binding ELISA plates (Corning) were coated with the GP- specific ...
11
The small nonstructural protein (NS2) of the parvovirus minute virus of mice is required for efficient DNA replication and infectious virus production in a cell-type-specific manner.
... Mutant viral stocks, passaged fewer than three times on NB324K cells, were next assayed for viral DNA replication compared with that of wild-type virus, following synchronized infection [r] ...
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Baculovirus Induces Type I Interferon Production through Toll-Like Receptor-Dependent and -Independent Pathways in a Cell-Type-Specific Manner
... of type I IFN in PECs upon infection with AcNPV was resistant to pretreatment with en- docytosis inhibitors, suggesting that the cytoplasmic recogni- tion of AcNPV by TLR-independent immune sensors may be required ...
12
Responsiveness of the Epstein-Barr virus NotI repeat promoter to the Z transactivator is mediated in a cell-type-specific manner by two independent signal regions.
... Localization of the coding region for an Epstein-Barr virus early antigen and inducible expression of this 60-kilodalton nuclear protein in transfected fibroblast cell lines.. Conformati[r] ...
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Inhibition of mTORC1 inhibits lytic replication of Epstein Barr virus in a cell type specific manner
... and Tor k17004 , which both decrease Tor levels [24,25]; the Tor DeltaP /+and Tor k17004 /+flies alone have wild-type- appearing eyes) the progeny had more wild-type eyes, suggesting that reduced Tor levels ...
10
Spike Protein VP8* of Human Rotavirus Recognizes Histo-Blood Group Antigens in a Type-Specific Manner
... The binding of VP8* was enhanced by fusion to the shell (S) or protruding (P) domains of NoV capsid protein. In our sepa- rate studies, we found that the norovirus (NoV) capsid protein can be used as an excellent ...
11
The Interferon-Stimulated Gene Ifi27l2a Restricts West Nile Virus Infection and Pathogenesis in a Cell-Type- and Region-Specific Manner
... and cytochrome c release (21). IFI6-16 (IFI6) is an ISG12 motif- containing family member that may share some functions with Ifi27l2a. In the context of DENV infection, a deficiency of IFI6-16 was associated with ...
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Pechloff, Konstanze (2013): Conditional in vivo expression of the fusion kinase ITK-SYK. Dissertation, LMU München: Fakultät für Biologie
... cell type specific manner, and to clarify its oncogenic potential in PTCL development, conditional gene targeting of the ROSA26 locus has been ...
131
Cardiovascular system in larval zebrafish responds to developmental hypoxia in a family specific manner
... determining the cardiovascular system's developmental response to the environment. It is therefore important to investigate developmental response in multiple genetic backgrounds. From an evolutionary perspective, under- ...
8
Sema3a1 guides spinal motor axons in a cell and stage specific manner in zebrafish
... In order for axons to reach their proper targets, both spatiotemporal regulation of guidance molecules and stepwise control of growth cone sensitivity to guidance molecules is required. Here, we show that, in zebrafish, ...
11
Synaptopodin regulates the actin bundling activity of α actinin in an isoform specific manner
... with 40 μl agarose beads coated with anti-FLAG-M2 antibody (Sigma- Aldrich) at 4°C for 2 hours. Beads were collected by centrifugation for 1 minute at 1,000 g and washed 5 times with 1 ml of IP buffer for 30 min on a ...
12
Modification of the Untranslated Regions of Human Enterovirus 71 Impairs Growth in a Cell-Specific Manner
... Sabin type 3 poliovirus has been shown to be a determinant of neu- rovirulence ...pheno- type. Another study reported SH-SY5Y cell-specific attenua- tion of poliovirus recombinants carrying a U at ...
11
Young scientists conference “Modern aspects of Biochemistry and Biotechnology – 2018”
... Mesenchymal type of migration implies spindle-like shape of cancer cells, as well as decom- position of extracellular matrix through increased expression levels and activity of extracellular ...
46
Tie1 attenuation reduces murine atherosclerosis in a dose dependent and shear stress–specific manner
... for specific locales of the distal aorta in PECAM-knockout mice on either the Apoe-deficient or the LDL receptor–deficient background (45, ...stress–specific manner, discriminating between different ...
13
Neuropilin2 regulates the guidance of post-crossing spinal commissural axons in a subtype-specific manner
... commissural neurons were shown to express the cell adhesion molecule L1 on both the pre- and post-crossing segments of their axons. Ultimately, the GAD65/L1- expressing post-crossing axons project rostrally within the ...
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Sphingomyelin Activates Hepatitis C Virus RNA Polymerase in a Genotype-Specific Manner
... Hepatitis C virus (HCV) replication and infection depend on the lipid components of the cell, and replication is inhibited by inhibitors of sphingomyelin biosynthesis. We found that sphingomyelin bound to and activated ...
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