Uncoupling protein 1 (UCP1)
Sequence and haplotypes variation of the ovine uncoupling protein-1 gene (UCP1) and their association with growth and carcass traits in New Zealand Romney lambs
... Abstract: Uncoupling protein-1 gene (UCP1) plays an important role in the regulation of thermogenesis, energy expenditure, and protection against oxidative ...separate UCP1 regions: ...
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Mitochondrial uncoupling protein 1 expression in thymocytes
... mitochondrial uncoupling protein 1 (UCP1) peptide, this study confirms the observation that UCP 1 is present in thymocytes isolated from UCP 1 wild-type, but not UCP 1 ...
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An investigation into the physiological expression and function of mitochondrial uncoupling protein 1 in thymus
... In our endeavours to understand the role of mitochondrial uncoupling protein 1 in thymocyte function, we compared cell profiles in thymus and spleen of wild-type mice with those of UCP 1[r] ...
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The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study
... detect Ucp1. PCR conditions for Ucp1 were: 95°C for 10 min, Hot-start, followed by 3 cycles of denaturation at 95°C for 30 sec, annealing at 54°C for 10 sec, extension at 72°C for 30 sec; another 3 cycles ...
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Mitochondrial uncoupling prevents cold induced oxidative stress: a case study using UCP1 knockout mice
... mitochondrial uncoupling protein 1 (UCP1) is driving ...(i.e. UCP1 activity) in the brown adipose tissue (BAT) of wild-type mice or by ATP-dependent muscular shivering thermogenesis in ...
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Augmenting energy expenditure by mitochondrial uncoupling: a role of AMP-activated protein kinase
... AMP-activated protein kinase (AMPK), the master regulator of cellular energy ...mitochondrial uncoupling in metabolically relevant tissues, especially in white adipose tissue (WAT), skeletal muscle (SM), ...
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<p>Aging-associated impairment in metabolic compensation by subcutaneous adipose tissue promotes diet-induced fatty liver disease in mice</p>
... of uncoupling protein 1 (UCP1), which dissi- pates chemical energy as ...heat. UCP1-expressing cells are divided into two categories: classical brown adipocytes and beige ...
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Recent progress in the study of brown adipose tissue
... activates protein kinase A, which, in turn, phosphorylates and activates triacylglycerol ...of uncoupling protein 1 (UCP1), a key component of ...thermogenesis. UCP1 activation ...
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The role of uncoupling protein 3 in human physiology
... by uncoupling protein 1 (UCP1) (previously known as uncou- pling protein or thermogenin), first cloned in 1985 ...(3). UCP1 localizes to the mitochondrial inner membrane and ...
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Weight loss and brown adipose tissue reduction in rat model of sleep apnea
... The uncoupling protein 1 (UCP1) existent in BAT cells makes possible for the mitochondria to release energy directly in heat form ...The UCP1 expression is regulated by cate- ...
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Nonshivering thermogenesis in the African lesser bushbaby, Galago moholi
... the uncoupling protein 1 (UCP1) alters proton conductance in the inner mitochondrial membrane and leads to heat generation instead of ATP production (Hansen and Knudsen, 1986; Heaton et ...
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Thermogenesis, food intake and serum leptin in cold exposed lactating Brandt's voles Lasiopodomys brandtii
... however, the evidence available at present does not unambiguously support either of them (Speakman and Król, 2005). The suppression of thermogenesis in brown adipose tissue (BAT), as shown by tissue hypotrophy, a ...
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Mitochondrial uncoupling protein 1 overexpression increases yield in Nicotiana Tabacum under drought stress by improving source and sink metabolism
... Overexpression of plant mitochondrial uncoupling protein in transgenic tobacco increases tolerance to oxidative stress.. Activation and function of mitochondrial uncoupling protein in pl[r] ...
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A quest for the origin of mammal uncoupling proteins
... mammals, uncoupling protein 1 (UCP1) is responsible for non- shivering thermogenesis in brown adipose tissue ...The protein is inserted with six ???-helical transmembrane domains into ...
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Genetic and epigenetic interactions in adaptive thermogenesis pathways in association with obesity from a Public Health Genomics perspective
... (adrB3), uncoupling protein 1 (ucP1), the transcription factors peroxisome proliferated activator receptor gamma (PParγ), peroxisome proliferated activator receptor gamma co-activator 1 ...
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Insights into brown adipose tissue evolution and function from non model organisms
... total protein, provides the engine to harvest oxidation energy from lipids and glucose (Rousset et ...mitochondrial uncoupling protein 1 (UCP1) acts as a valve to rapidly release this ...
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Effects of metformin on metabolism of white and brown adipose tissue in obese C57BL/6J mice
... mitochondria. Uncoupling protein 1 (UCP-1), which exclusively expressed in the inner membrane of the mito- chondria in brown adipocytes, mediates energy expendi- ture and heat ...
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Anti-obesity efficacy of nanoemulsion oleoresin capsicum in obese rats fed a high-fat diet
... PCR Master Mix was obtained from Qiagen (Germantown, MD, USA). Kits for the analysis of aspartate aminotrans- ferase (AST), alanine aminotransferase (ALT), triglycerides (TGs), and total cholesterol (TC) were purchased ...
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Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice
... brane protein VDAC1, and non-mitochondrial protein β-actin in pre-pubertal (1-month-old), pubertal (5- month-old), and post-pubertal (10-month-old) B6 mice of different sex at physiological ...file ...
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The Role of Mitochondrial Uncoupling Protein 3 in T Cell Function
... Nancy-520 was warmed to RT. For genotyping experiments and reverse transcription (RT)-PCR experiments, 1.5 or 2.5 % (w/v) agarose gels were prepared by boiling 1.5 or 2.5 grams (g), respectively, of agarose in 100 mL of ...
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