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Valosin-containing protein (VCP)

Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes

Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes

... for valosin-containing protein (VCP/p97) in early steps of ...of VCP inhibits a previously uncharacterized degradation of the nucleocapsid N ...for VCP in the maturation of ...

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Affinity Purification of the Hepatitis C Virus Replicase Identifies Valosin-Containing Protein, a Member of the ATPases Associated with Diverse Cellular Activities Family, as an Active Virus Replication Modulator

Affinity Purification of the Hepatitis C Virus Replicase Identifies Valosin-Containing Protein, a Member of the ATPases Associated with Diverse Cellular Activities Family, as an Active Virus Replication Modulator

... identified valosin-containing protein (VCP), a member of the ATPases associated with diverse cellular activities (AAA ⴙ ATPase) family, as an active viral replication modulator whose ATPase ...

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Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons

Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons

... encoding valosin-containing protein (VCP) lead to multisystem proteinopathies including fronto- temporal ...derived VCP mutant fibroblasts exhibit lower mitochondrial membrane ...

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Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal

Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal

... Valosin-containing protein (VCP)/p97 is a ubiquitously expressed protein belonging to the AAA+ (ATPases As- sociated with diverse cellular Activities) protein family with two ...

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Sorafenib Impedes Rift Valley Fever Virus Egress by Inhibiting Valosin-Containing Protein Function in the Cellular Secretory Pathway

Sorafenib Impedes Rift Valley Fever Virus Egress by Inhibiting Valosin-Containing Protein Function in the Cellular Secretory Pathway

... p97/ valosin-containing protein (VCP), which is involved in membrane remodeling in the secretory pathway and a known target of sorafenib, was found to be impor- tant for RVFV ...of VCP ...

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Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant

Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant

... Valosin-containing protein (VCP) is a ubiquitous member of the AAA-ATPase supergene ...family. VCP is known to play an important role in cellular activities including ubi- quitin (Ub) ...

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Original Article Associations of valosin-containing protein gene polymorphisms with hepatocellular carcinoma: a case-control study in a Chinese Han population

Original Article Associations of valosin-containing protein gene polymorphisms with hepatocellular carcinoma: a case-control study in a Chinese Han population

... operation. Valosin-containing protein (VCP) is a member of the ATPase associated with lots of cellu- lar activities (AAA) ...eukaryotes. VCP has a significant association with ...

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Upregulation of valosin-containing protein (VCP) is associated with poor prognosis and promotes tumor progression of orbital B-cell lymphoma

Upregulation of valosin-containing protein (VCP) is associated with poor prognosis and promotes tumor progression of orbital B-cell lymphoma

... lysates containing 15 µ g protein were heated for 5 minutes at 100 ° C, separated by 12% SDS-PAGE, and transferred onto polyvinylidene difluoride membranes (Immobilon-P; Millipore, Billerica, MA, ...

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From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation

From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation

... and VCP and the regulation of dendritic spinogenesis has provided the first molecular evidence that VCP functions as a genetic modifier for ...of VCP as a downstream effec- tor of ...

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Valosin containing protein and neurofibromin interact to regulate dendritic spine density

Valosin containing protein and neurofibromin interact to regulate dendritic spine density

... of VCP knockdown on spine ...ed VCP-knockdown neurons was comparable to that of neurons treated with lovastatin alone (Figure 9, A and ...In VCP-knock- down neurons, 5 μM lovastatin treatment ...

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Valosin-Containing Protein (VCP/p97) Is Required for Poliovirus Replication and Is Involved in Cellular Protein Secretion Pathway in Poliovirus Infection

Valosin-Containing Protein (VCP/p97) Is Required for Poliovirus Replication and Is Involved in Cellular Protein Secretion Pathway in Poliovirus Infection

... (EGFP)-fused VCP mutants [wild-type (wt) VCP, VCP(K524A), VCP(R191Q), and VCP(A232E), constructed based on mouse VCP se- quence that has 100% amino acid similarity to human ...

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Another VCP interactor: NF is enough

Another VCP interactor: NF is enough

... the valosin- containing protein (VCP) ...multifunctional protein lead to the degeneration of disparate tissues is unclear. VCP participates in diverse cellular functions by ...

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The Basis of VCP-Mediated Degeneration: Insights From a Drosophila Model of Disease

The Basis of VCP-Mediated Degeneration: Insights From a Drosophila Model of Disease

... Valosin-containing protein (VCP) is a highly conserved molecular chaperone that regulates a wide array of essential cellular ...in VCP are causative of degenerative disease that can ...

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Point-of-care test for cervical cancer in LMICs

Point-of-care test for cervical cancer in LMICs

... and protein concentrations were determined with the bicinchoninic acid (BCA) protein assay (Thermo Fisher Scientific, Rockford, ...of protein (1μg per lane) were electrophoresed by 10% sodium dodecyl ...

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The involvement of endoplasmic reticulum formation and protein synthesis efficiency in VCP- and ATL1-related neurological disorders

The involvement of endoplasmic reticulum formation and protein synthesis efficiency in VCP- and ATL1-related neurological disorders

... including Valosin-containing protein (VCP), Atlastin-1 (ATL1), Spastin (SPAST), Reticulon 2 (RTN2), Receptor expression enhancing protein 1 (REEP1) and RAB10 — suggesting a critical ...

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Plasma Membrane Microdomains Containing Vesicular Stomatitis Virus M Protein Are Separate from Microdomains Containing G Protein and Nucleocapsids

Plasma Membrane Microdomains Containing Vesicular Stomatitis Virus M Protein Are Separate from Microdomains Containing G Protein and Nucleocapsids

... G protein cytoplasmic domain and the lack of concrete M protein and G protein association data suggest that M protein interacts with G pro- tein indirectly through membrane ...anti-M ...

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Surfactant Trials

Surfactant Trials

... As Dr Kattwinkel points out, the simplistic approach of delivering only phospholipids to infants with surfac- tant deficiency did not prevent or ameliorate respiratory distress syndrome (RDS). It was only with ...

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Design and Implementation of Virtualized Code Protection(VCP) [foryou2008] pdf

Design and Implementation of Virtualized Code Protection(VCP) [foryou2008] pdf

... VCP 는 프로그램의 주요 코드 영역(Sensitive Code Block)을 리버스 코드 엔지니어링 으로부터 보호하기 위해, VM 만이 해석할 수 있는 가상화된 코드 영역(Virtualized Code Block)으로 변환(Binary Translation)한다. 변환은 런타임(Dynamic)에 이루 어지는 것이 아니라 그 이전(Static)에 이루어진다. 인텔 코드 ...

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Characterization of Adaptor Binding and Substrate Processing by VCP/p97

Characterization of Adaptor Binding and Substrate Processing by VCP/p97

... inclusions containing ubiquitin and other proteins such as Tar DNA binding protein-43 ...inclusions containing ubiquitin, TDP-43, and tau cause loss of reasoning, judgement, and social awareness in ...

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Airports economic efficient frontier

Airports economic efficient frontier

... Table 6 also shows that all variables have zero slack, meaning that for this particular combination of vari- ables, VCP could efficiently minimize inputs or maxi- mize outputs in order to achieve total ...

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