Vascular smooth muscle cell migration
Rapamycin inhibits vascular smooth muscle cell migration
... SMC migration is also an important com- ponent of the intimal thickening after ...SMC migration we examined the ability of cells to migrate out of porcine aortic explants and establish ...in cell ...
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The inhibition of vascular smooth muscle cell migration by peptide and antibody antagonists of the alphavbeta3 integrin complex is reversed by activated calcium/calmodulin dependent protein kinase II
... sphere. After 24 h, the virus-containing medium was replaced with vi- rus-free medium and the cells collected for analysis of expression or for migration assays. Under the conditions described above, no cyto- ...
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Mouse Cytomegalovirus M33 Is Necessary and Sufficient in Virus-Induced Vascular Smooth Muscle Cell Migration
... of vascular SMCs induces their mi- gration ...AoSMC migration in MCMV-infected cells, expression of M33 was sufficient to induce migration to levels similar to MCMV ...enhanced migration, ...
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Sulforaphane Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Migration via Suppression of NOX4/ROS/Nrf2 Signaling
... and migration of human vascular smooth muscle cells ...abnormal migration of HVSMCs as well as the underlying mechanisms of those ...and migration were inhibited by treatment ...
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The role of focal adhesion kinase in vascular smooth muscle cell migration
... Rac1 activity is necessary and sufficient for cortical translocation of cortactin, and is also required for the phosphorylation of the major Src phosphorylation sites 61,62 . As one might expect, evidence suggests that ...
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Sequence independent inhibition of in vitro vascular smooth muscle cell proliferation, migration, and in vivo neointimal formation by phosphorothioate oligodeoxynucleotides
... of vascular smooth muscle cell (SMC) proliferation when targeted against differ- ent ...vitro migration in a modified micro-Boyden ...and migration as well as in vivo neointimal ...
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The vascular smooth muscle cell: A therapeutic target in type 2 diabetes?
... in vascular diseases (reviewed recently in ...the vascular SMC are miR-143/145, products of the same bicistronic gene that are known to be highly expressed in the vascular wall, particularly in SMC ...
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Adipocytes modulate vascular smooth muscle cells migration potential through their secretions
... of vascular smooth muscle cells (VSMC) is recognized as a predisposition factor for atherosclerosis ...VSMC migration and phenotypic swit- ching, which may increase the incidence of athe- ...
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Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia
... Vascular smooth muscle cell (VSMC) proliferation and mi- gration are responses to arterial injury that are highly im- portant to the processes of restenosis and ...PDGF-BB–directed ...
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Regulation Of The Human Vascular Smooth Muscle Cell Transcriptome By Extracellular Matrix Stiffness
... sequencing of RNA from Ao and Co VSMCs grown on engineered polyacrylamide hydrogel surfaces tuned to physiologic and pathologic stiffness. Using several bioinformatic approaches, we compared the transcriptional ...
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The growth and differentiation of aortal smooth muscle cells after calcitriol treatment are associated with microtubule reorganisation - an in vitro study
... The smooth muscle cells (SMCs) of the arterial media play a predominant role in functional and structural alterations of the arterial ...the vascular smooth muscle cells, namely ...
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PubMedCentral-PMC5009267.pdf
... in vascular smooth muscle cells has important physiological ...During vascular injury, activated platelets or other cells pro- duce TxA2, which in turn promotes platelet activation and ...
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Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration
... PDGF-induced vascular SMC migration, which is in line with the observation of increased ERK expression in the precapillary arteries of MCT-treated rats (data not ...
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Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation
... and migration, as evi- denced by the absence of myofibroblasts from the primary alveolar septa in PDGF-A-null mice, resulting in severe alveolarization defects (7, 22, ...myofibroblast migration, we ...
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Original Article Transcription factor Mef2C regulates the migration of vascular smooth muscle cells
... abnormal migration of vascular smooth muscle cells (VSMCs) plays an important role in the pathophysiology of many vascular ...the migration of primary VSMCs. Cell ...
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A spleen tyrosine kinase inhibitor attenuates the proliferation and migration of vascular smooth muscle cells
... and migration based on the results of multiple experiments, such as cell proliferation assays, wound heal- ing assays, and transwell migration assays, that assessed the anti-proliferative and ...
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Original Article Atorvastatin inhibits PDGF-BB induced vascular smooth muscle cells proliferation and migration in cerebrovascular diseases
... KLF4 is involved with many cellular processes, including tumor development, stem cell biology, and inflammatory endothelial activation [30- 32]. In VSMCs, KLF4 both promotes prolifera- tion and induced VSMCs ...
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Original Article MiR-21 facilitates the proliferation of smooth muscle cells and atherosclerotic plaque formation by suppressing PTEN to activate AKT
... dothelial cell injury by facilitating cell autopha- gy ...endothelial cell proliferation and migration by modulating miR-21 ...facilitate cell apoptosis, plaque necrosis, and ...
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MicroRNA-186-5p serves as a diagnostic biomarker in atherosclerosis and regulates vascular smooth muscle cell proliferation and migration
... The subjects were 104 patients with asymptomatic atherosclerosis and 80 healthy controls. The diagnosis of atherosclerosis was based on the value of the carotid intima- media thickness (CIMT) of the common carotid ...
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Bo Gan Whan regulates proliferation and migration of vascular smooth muscle cells
... EZ-Cytox Cell Viability Assay Kit were purchased from Daeil Lab Service (Seoul, Korea) and cell culture ma- terials were purchased from Gibco-BRL (Gaithersburg, MD, USA), ...
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