Viral and host factors:
Viral and Host Factors in Human Respiratory Syncytial Virus Pathogenesis
... of viral versus various host factors to RSV pathogenesis remains ...direct viral cytopathology, exaggerated CTL responses, imbalanced Th2/Th1 responses, exaggerated in- flammatory responses, ...
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Role of viral and host factors in interferon based therapy of hepatitis C virus infection
... the host factors, the most prominent associations are polymorphisms within the region of the interleukin 28B (IL28B) gene, but variations in other cytokine genes have also been linked with the treatment ...
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Both Viral and Host Factors Contribute to Neurovirulence of Bovine Herpesviruses 1 and 5 in Interferon Receptor-Deficient Mice
... the factors responsible for efficient viral replication in neurons, which are contributed by the gamma interferon ...either viral or host factors may be of general importance, given the ...
10
Chronic hepatitis B virus and hepatitis C virus infections and cancer: synergy between viral and host factors
... of viral replication and virus-directed immunity in the case of HBV infection, while being more closely associated with host factors such as meta- bolic dysfunctions and fibrotic processes in the case ...
6
Identification of host factors in swine respiratory epithelial cells that contribute to host anti-viral defense and influenza virus replication
... the viral ion channel protein M2 (rimantadine and amantadine) (102, ...cellular host factors instead of targeting the traditional virus ...cycle, host-factors are ...cellular ...
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RPLP1 and RPLP2 Are Essential Flavivirus Host Factors That Promote Early Viral Protein Accumulation
... putative host factors required for DENV and YFV ...essential host factors for DENV, YFV, and ZIKV infection in two human cell lines: A549 lung adenocarcinoma and HuH-7 hepatoma cells, and for ...
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Thiouracil Cross-Linking Mass Spectrometry: a Cell-Based Method To Identify Host Factors Involved in Viral Amplification
... identify host factors that are func- tionally associated with the viral ...RNA viral families that do not require host cell transcription or a DNA-dependent RNA polymerase dur- ing ...
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Multiple Host Factors Interact with the Hypervariable Domain of Chikungunya Virus nsP3 and Determine Viral Replication in Cell-Specific Mode
... with host factors and their roles in viral replica- tion in vertebrate and mosquito ...These host fac- tors include two members of the G3BP family and their mosquito homolog Rin, two members ...
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Computational Analysis of RNAi Screening Data to Identify Host Factors Involved in Viral Infection and to Characterize Protein-Protein Interactions
... detect host factors (human proteins) that support virus growth and replication of cells infected with the Hepatitis C virus ...of viral infection, several RNAi experiments of viral-infected ...
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Causes and Consequences of Spatial Within-Host Viral Spread
... of viral spread within ...of viral spread for pathogens of the respiratory ...possible factors that structure the dynamics of this spatial ...what viral and host factors may ...
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Characterization of P1 leader proteases of the Potyviridae family and identification of the host factors involved in their proteolytic activity during viral infection
... the viral protease (Pro) and their cleavage sites, but still much is left to know about the specific involvement of these proteases in viral ...genome-linked viral protein (VPg) domains; whether this ...
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The Role of Viral, Host, and Secondary Bacterial Factors in Influenza Pathogenesis
... involving host, viral, and bacterial factors. Host factors that enhance risk of severe influenza disease include underlying comorbidities, such as cardiac and respiratory disease, ...
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Cumulative Impact of Host and Viral Factors on HIV-1 Viral-Load Control during Early Infection
... ulated by human genetic factors in both the SC and the TSP. In the newly infected SC, HIV-specific CD8 ⫹ T-cell responses, facilitated by specific HLA class I (HLA-I) molecules, clearly have a substan- tial ...
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Host and Viral Determinants of Mx2 Antiretroviral Activity
... with host factors, residues P207, G208, and T210 form the majority of a solvent accessible loop between helices 10 and ...the host cytosol in the context of the mature fullerene core, albeit at a ...
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Suppression of Viral RNA Recombination by a Host Exoribonuclease
... individual host genes based on the Saccharomyces cerevisiae single-gene deletion library identified five host genes whose absence led to a 10- to 50-fold enhancement in viral recombinant RNA ...
10
Host Factors in Coronavirus Replication
... the host to create an optimal environment for coronavirus replication, alter host gene expression and counteract antiviral ...influence viral pathogenesis and will ultimately determine the outcome of ...
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Viral and host proteins involved in picornavirus life cycle
... cause viral instability or uncoating, but probably result in the aggregation of other receptors, or trigger the subsequent ...intracellular host factors is also ...apoptosis, viral spread, and ...
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Host Factors in Enterovirus 71 Replication
... The 2C protein is one of the most highly conserved proteins among the picornaviruses (4). The amino acid sequence of EV71 2C shares 65% similarity with that of poliovirus. Like the 2C protein of PV, EV71 2C plays an ...
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Host factors against plant viruses
... on host resources and ...target viral components. Viral factors work in synchrony with pro-viral host factors during the infection cycle and are targeted by antiviral ...
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Viral Evasion and Manipulation of Host RNA Quality Control Pathways
... between viral RNAs and cel- lular quality control proteins gives insight into the constraints governing viral evolution, viral RNAs have long been used to dis- cover and dissect cellular gene ...
9