Virus structure and replication
Role of the N-Terminal Zinc Finger of Human Immunodeficiency Virus Type 1 Nucleocapsid Protein in Virus Structure and Replication
... of the wt level for both mutants, which is similar to levels found in other studies involving mutations of the Zn 21 -chelating res- idues (data not shown) (27, 35). The implications of NCp7 in the reverse transcription ...
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Concatameric replication of Epstein-Barr virus: structure of the termini in virus-producer and newly transformed cell lines.
... AG876 linear virion DNA circularized after infection of neonatal lymphocytes and adult peripheral blood lympho- blastoid cells to form predominant fused terminal fragments. that varied i[r] ...
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Structure of the Picornavirus Replication Platform: A Potential Drug Target for Inhibiting Virus Replication
... the virus is endemic in parts of the world and outbreaks have recently increased in California due to the rising homeless population and fecal-contaminated environments 7 ...disease virus, is a highly ...
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Low-Resolution Structure of Vaccinia Virus DNA Replication Machinery
... variola virus is a highly lethal disease that marked human history and was eradicated in 1979 thanks to a worldwide mass vaccination ...This virus remains a significant threat for public health due to its ...
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Coalescence of the Sites of Cowpea Mosaic Virus RNA Replication into a Cytopathic Structure
... during the course of CPMV infection. Early in infection, the fluorescent probe that recognizes plus-strand RNA was present at numerous subcellular sites distributed over the cy- toplasm that quickly coalesced into a ...
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The Nucleotides on the Stem-Loop RNA Structure in the Junction Region of the Hepatitis E Virus Genome Are Critical for Virus Replication
... (SL) structure in the intergenic region of the hepatitis E virus (HEV) genome in virus replication were determined by using Huh7 cells transfected with HEV SL mutant replicons containing ...
5
A pseudoknot ribozyme structure is active in vivo and required for hepatitis delta virus RNA replication.
... delta virus (HDV) have so far been studied primarily in ...HDV replication cycle have not been ...ribozyme structure likely exists and functions during the HDV replication cycle in ...the ...
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H-1 Parvovirus-Associated Replication Bodies: a Distinct Virus-Induced Nuclear Structure
... nuclear structure that is induced after infection with the autonomous parvovirus ...H-1 virus which is essential for viral DNA amplification colocalized with virus-specific DNA sequences and sites of ...
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Infectious Bursal Disease Virus Hijacks Endosomal Membranes as the Scaffolding Structure for Viral Replication
... viral replication cycle by profiting from a reverse genetic approach developed by Rodríguez Aguirre’s laboratory to generate P2-mutated viral progeny ...overall structure of the ...the replication of ...
22
DNA Virus Replication Compartments
... Ongoing replication requires the recruitment of different vi- ral and cellular proteins to the virus-induced foci, which mature to viral replication centers ...so-called virus-induced chap- ...
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Populations of Genomic RNAs Devoted to the Replication or Spread of a Bipartite Plant Virus Differ in Genetic Structure
... for replication, while the other regions studied are in ...two-component virus, which means that during infection genomic segments 1 and 2 are separately ...RNA1 replication before meeting RNA2 would ...
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Replication of Western Equine Encephalomyelitis Virus II. Cytoplasmic Structure Involved in the Synthesis and Development of the Virions
... Analysis of the cytoplasmic fraction of chick embryo cells during the ex- ponential phase of Western equine encephalomyelitis (WEE) virus growth showed that the viral ribonucleic acid (R[r] ...
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Structure and Function of the 3′ Terminal Six Nucleotides of the West Nile Virus Genome in Viral Replication
... WN virus replicon containing a Renilla luciferase reporter to define the requirement of se- quence and base-pairing structure of the 3⬘-terminal 6 nt (5⬘- GGAUCU OH -3⬘) of the genome in viral ...and ...
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Role of RNA Structure and RNA Binding Activity of Foot-and-Mouth Disease Virus 3C Protein in VPg Uridylylation and Virus Replication
... Blackett Laboratory, Imperial College, South Kensington Campus, London SW7 2AZ, United Kingdom 3 Received 17 March 2006/Accepted 7 July 2006 The uridylylation of the VPg peptide primer is the first stage in the ...
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A 5' proximal Stem loop Structure of 5' Untranslated Region of Porcine Reproductive and Respiratory Syndrome Virus Genome Is Key for Virus Replication
... N-SL2-like structure, N-SL2 ’ , which further signifies the high-order structural nature of N- ...syndrome virus genomic RNA can be specifi- cally bound by the 3a protein, and a 55-kDa cellular protein has ...
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Genetic Analysis of Murine Hepatitis Virus nsp4 in Virus Replication
... in virus replication were not observed for ...in virus yield and a delay in viral RNA synthesis levels that reached only approximately half the synthesis levels of wild-type ...overall ...
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Architecture of Replication Compartments Formed during Epstein-Barr Virus Lytic Replication
... lytic replication origin is unwound by an unknown mechanism, viral replication proteins initiate to syn- thesize the viral ...with replication forks on the replicating EBV ...within ...
10
Formation of a cruciform structure at the simian virus 40 replication origin abolishes T-antigen binding to the origin in vitro.
... The 250-bp wild-type (WT) and 249-bp mutant pRGM29 (29) MboIIlMspI fragments, each 5' end labeled at the MboII site at pBR322 nucleotide 4346, were subjected. to DNase footprint analysis[r] ...
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A bulged stem-loop structure in the 3' untranslated region of the genome of the coronavirus mouse hepatitis virus is essential for replication.
... hepatitis virus (MHV) contains sequences that are necessary for the synthesis of negative-strand viral RNA as well as sequences that may be crucial for both genomic and subgenomic positive-strand RNA ...secondary ...
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The 3′-Terminal Structure Required for Replication of Barley Yellow Dwarf Virus RNA Contains an Embedded 3′ End
... examining replication only at 24 h postinoculation (hpi) in plant cells that have been inundated with large quantities of ...of replication that take place in whole plant infections, more fit structures ...
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