white adipose tissue
HMGA2 expression in white adipose tissue linking cellular senescence with diabetes
... of white adipose tissue (WAT), and dia- betes type 2 (T2D), the mechanisms by which an excess of adipose tissue contributes to the onset of the metabolic syndrome are as yet far away ...
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Sex differences in sympathetic innervation and browning of white adipose tissue of mice
... In this study, we examined lipid metabolism and browning of abdominal and subcutaneous WAT depots in male and female mice during β3-adrenergic stimula- tion. The selective β3-adrenergic receptor agonist CL316,243 (CL) ...
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Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
... The white adipose organ is composed of both subcutaneous and several intra-abdominal ...Brown adipose produces heat as a defense against hypothermia and obesity, and the appearance of brown-like ...
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Hormonal factors in the control of the browning of white adipose tissue
... Adipose tissue has historically been classified into energy-storing white adipose tissue (WAT) and energy- dissipating brown adipose tissue (BAT) ...oxidative tissue ...
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Characterization and properties of ecto-5' nucleotidase in white adipose tissue
... When thyroid states were altered in the rat models, changes in e S ’Nase activity were not so apparent. H y p o t h y roidism was induced as described in Chapter 2, by the introduction of 6-n-propylthiouracil into the ...
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Cold induced changes in gene expression in brown adipose tissue, white adipose tissue and liver
... thermogenic tissue, brown adipose tissue (BAT) which is activated by the sympathetic nervous system during cold exposure and produces heat as a result of the BAT-specific expression of uncoupling ...
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Direct effects of leptin on brown and white adipose tissue
... and white adipose tissue (BAT and WAT, respectively) at the metabolic and molecular ...in adipose tissue was substantiated by the detection of its transcripts by RT-PCR, and leptin ...
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NPC1 in human white adipose tissue and obesity
... Background: Genetic studies have implicated the NPC1 gene (Niemann Pick type C1) in susceptibility to obesity. Methods: To assess the potential function of NPC1 in obesity, we determined its expression in abdominal ...
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Evaluation of markers of beige adipocytes in white adipose tissue of the mouse
... Inguinal adipose tissue from male C57Bl/6 mice was minced and digested in ...into white adipocytes employing the same cul- ture medium containing ...the white adipocytes were cultured for an ...
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Alternative Mechanism for White Adipose Tissue Lipolysis after Thermal Injury
... the white adipose tissue (WAT) interacts with the liver via inflammatory and metabolic signals leading to profound hepatic alterations, including hepatocyte apoptosis and hepatic fatty ...
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Cold-induced lipid dynamics and transcriptional programs in white adipose tissue
... of adipose tissue to produce heat is a dynamic process that continues to increase with pro- longed cold exposure, only reaching maximal capacity after several weeks ...
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Phytochemicals as novel agents for the induction of browning in white adipose tissue
... Another flavonoid found to have beneficial anti-obesity effects is quercetin (3,3′,4′,5,7-pentahydroxyflavone). Commonly found in high concentrations in apples, broc- coli, berries, onions, leafy vegetables and ...
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Changes in white adipose tissue metabolism induced by resveratrol in rats
... Extraction and analysis of RNA and quantification by reverse transcription-polymerase chain reaction (RT-PCR) Total RNA was isolated from 100 mg of epididymal adi- pose tissue using Trizol (Invitrogen, Carlsbad, ...
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Fto Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice via Alterations in Gut Microbiota
... Fto (fat mass and obesity-associated gene) is the first obesity-susceptibility gene to be identified via a genome-wide association study in 2007 [8], single-nucleotide polymorphisms (SNPs) in the first intron exhibited a ...
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Flavan-3-ol fraction from cocoa powder promotes mitochondrial biogenesis in skeletal muscle in mice
... brown adipose tissue was also induced significantly by flavan- 3-ols treatment, whereas UCP-2 in liver and white adipose tissue and UCP-3 in skeletal muscle remained largely unchanged ...
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Recent progress in the study of brown adipose tissue
... roles, adipose tissue in mam- mals is categorized into white adipose tissue (WAT) and brown adipose tissue (BAT) ...
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Understanding and evaluating cardio metabolic benefits imposed by surgery, medication and adipose tissue metabolism
... on white adipose tissue metabolism and inflammation, which would appear to enhance this anti-diabetic medication as an effective anti-obesity agent as ...adipocytes, adipose specific AGT ...
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Extrinsic and intrinsic regulation of DOR/TP53INP2 expression in mice: effects of dietary fat content, tissue type and sex in adipose and muscle tissues
... Methods: To identify sites of differential DOR expression in metabolically active tissues, we measured differences in DOR expression in white adipose tissue (WAT), brown adipose tissue ...
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Autophagy regulates adipose mass and differentiation in mice
... of white and brown adipose tissue can profoundly affect lipid stor- age and whole-body energy ...in adipose differentiation was therefore examined in the current study by genetic inhibition of ...
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Dicarbonyl stress in clinical obesity
... in white adi- pose tissue and liver may be a mediator of obesity and insulin resistance and thereby a risk factor for development of type 2 diabetes and non-alcoholic fatty liver ...on adipose ...
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