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white matter

The Contributions of MRI Based Measures of Gray Matter, White Matter Hyperintensity, and White Matter Integrity to Late Life Cognition

The Contributions of MRI Based Measures of Gray Matter, White Matter Hyperintensity, and White Matter Integrity to Late Life Cognition

... that white matter in- tegrity has no direct bearing on late-life cognition; indeed, WMHs have been shown to impact cognitive function in the absence of severe GM atrophy, 37 and white matter ...

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Cerebral White Matter Disruption in Creutzfeldt Jakob Disease

Cerebral White Matter Disruption in Creutzfeldt Jakob Disease

... that white matter pathways between the injured gray matter sites are affected in CJD, but robust evi- dence has been lacking until ...reflect white matter ...

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Cavernous Carotid Artery Calcification and White Matter Ischemia

Cavernous Carotid Artery Calcification and White Matter Ischemia

... advanced white matter grade once one adjusts for ...imaging white matter scores are linked through the effect of age and do not have an independent relationship in the genders and races ...

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A crucial role for Olig2 in white matter astrocyte development

A crucial role for Olig2 in white matter astrocyte development

... Gfap expression was initially observed in cells scattered throughout the cortex at neonatal stage P7 (Fig. 2B), and increased dramatically from postnatal week 2 (Fig. 2D). High Gfap expression persists throughout ...

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White Matter Correlates of Cognitive Impairment in Essential Tremor

White Matter Correlates of Cognitive Impairment in Essential Tremor

... An F-test performed among the 3 groups was found to be statis- tically significant in mean diffusivity, radial diffusivity, and axial diffusivity, while it was not significant for fractional anisotropy. On post hoc t ...

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White matter changes caused by chronic solvent abuse

White matter changes caused by chronic solvent abuse

... We studied 15 men and five women with a history of solvent abuse for at least 1 year. Informed consent was obtained from each patient before the examinations. The diagnoses were confirmed by histories carefully taken ...

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White matter involvement in a family with a novel PDGFB mutation

White matter involvement in a family with a novel PDGFB mutation

... of white matter hyperintensity in the frontal and parietal lobes associated with small cystic lesions ...of white matter hyperintensity associated with small cystic lesions in the ...

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Original Article Periventricular rather than deep white matter hyperintensities are associated with white matter lesion relevant vascular cognitive impairment

Original Article Periventricular rather than deep white matter hyperintensities are associated with white matter lesion relevant vascular cognitive impairment

... Quantitative data was presented as mean ± SD. All statistical analyses were conducted using the Statistical Package for the Social Sciences (SPSS) version 19 (SPSS IBM, New York, NY). Comparisons of subject characteris- ...

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Morphology Specific Discrimination between MS White Matter Lesions and Benign White Matter Hyperintensities Using Ultra High Field MRI

Morphology Specific Discrimination between MS White Matter Lesions and Benign White Matter Hyperintensities Using Ultra High Field MRI

... The control cohort in our study was selected from a pool of age-matched, self-reported healthy individuals, with no known neurologic disorders. Incidental findings of WML in these indi- viduals (63 lesions of ⬎ 3 mm and ...

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Whole blood gene expression and white matter Hyperintensities

Whole blood gene expression and white matter Hyperintensities

... In conclusion, we performed a large-scale profiling of gene expression in whole blood in a large community- based cohort, and identified 13 genes whose expression was associated with WMH. Our results are consistent with ...

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Multivariate white matter alterations are associated with epilepsy duration

Multivariate white matter alterations are associated with epilepsy duration

... Collectively, our results show that the Mahalanobis distance can be used alongside the traditional univariate analyses for a more complete understanding of the progressive nature of epilepsy and its association with ...

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Unique microglia expression profile in developing white matter

Unique microglia expression profile in developing white matter

... in white matter regions are essential for proper oli‑ godendrocyte homeostasis and myelinogenesis in the first postnatal ...both, white matter and grey matter microglia during ...

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Cortical tau load is associated with white matter hyperintensities

Cortical tau load is associated with white matter hyperintensities

... Results: 36 human post-mortem right fixed cerebral hemispheres (mean age 84.4 ± 7.7 years; male: 16, female: 20) containing varying amounts of AD-pathology (AD: 23, controls: 13) underwent T2- weighted MRI with WMH ...

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Loss of USP18 in microglia induces white matter pathology

Loss of USP18 in microglia induces white matter pathology

... the white matter seems to be prevalent [5, ...the white matter. The escalating spiral of white matter damage might be initiated by type I IFN that is induced in microglia via ...

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Effects of white matter microstructure on phase and susceptibility maps

Effects of white matter microstructure on phase and susceptibility maps

... There are many potential applications of QSM due to the sensitivity of susceptibility maps to a range of endogenous biomarkers such as myelin (24,25), calcification (26), and iron content (8,27). A recent postmortem ...

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Radiation Effects on Cerebral White Matter: MR Evaluation

Radiation Effects on Cerebral White Matter: MR Evaluation

... When these supratentorial peri ventricular white-matter changes were compared in each age subgroup , statistically significant p < .005 differences were noted between the radiotherapy an[r] ...

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Effects of Age and Gender on White Matter Integrity

Effects of Age and Gender on White Matter Integrity

... about 20% of all oligodendrocytes in the adult corpus callo- sum are generated during adulthood, and 5% of adult-born oligodendrocytes in the cerebral cortex appear to be involved in elaboration of the myelin sheath. We ...

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Cystlike white matter lesions in tuberous sclerosis

Cystlike white matter lesions in tuberous sclerosis

... of white matter dys- plastic lesions of tuberous sclerosis or represent focal enlargement of perivascular spaces or pa- renchymal neuroepithelial ...nodules, white matter dysplasias, and ...

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Method for Combining Information from White Matter Fiber Tracking and Gray Matter Parcellation

Method for Combining Information from White Matter Fiber Tracking and Gray Matter Parcellation

... whole white matter fiber bun- dles, seeds points were assigned at all the voxels inside the white matter segmented by using SPM99 (Wellcome Depart- ment of Imaging Neuroscience, UK; see ...

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A Method for Clustering White Matter Fiber Tracts

A Method for Clustering White Matter Fiber Tracts

... then, white matter tractography was performed by using the Runge-Kutta method to interpolate paths (fiber traces) following the major directions of diffusion, in which traces were seeded only within the ...

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