whole genome
Selective Whole Genome Amplification Is a Robust Method That Enables Scalable Whole Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples
... ABSTRACT Whole-genome sequencing (WGS) of microbial pathogens from clin- ical samples is a highly sensitive tool used to gain a deeper understanding of the biology, epidemiology, and drug resistance ...
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Comparative analysis of copy number detection by whole-genome BAC and oligonucleotide array CGH
... costs. One of the most important characteristics of each platform is the detection rate of clinically significant alterations. Our results demonstrate that our whole- genome oligo array was able to detect ...
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Thermodynamically optimal whole genome tiling microarray design and validation
... the whole transcriptome of ...a whole‑genome tiling microarray can be designed using only genomic sequences without gene annotations, and it can be used to detect novel RNA transcripts as well as ...
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Whole genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes
... short-read whole-genome sequencing data from the Ag1000G Phase 2 data set to find genomic regions with increased read coverage relative to the genomic average, controlling for GC richness and excluding 27 ...
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Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification
... human whole blood; N = 8) to determine which set gives optimal genome amplifica- tion and ...1b). Whole genome sequencing of the amplified products were used to compared the quality of ...
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Information Dynamics of Whole Genome Adaptation
... As a structured, dynamic information system, the information dynamics of the whole genome determines adap- tation in a given environment. Genomic information is encoded in patterns of sequence variation. ...
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Forensic Applications of Whole Genome Amplification
... based whole genome amplification method could provide a better result than, for example, using 50 PCR cycles, which would lead to further complications with respect to interpreting the ...
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Transmission and Microevolution of USA300 MRSA in U S Households: Evidence from Whole Genome Sequencing
... performed whole-genome sequencing (WGS) of 146 USA300 MRSA isolates from SSTIs and colonization cultures obtained from an investigation conducted from 2008 to 2010 in Chicago and Los Angeles households that ...
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Whole-genome sequence of Schistosoma haematobium
... coordinated genome assembly and annotation. L.Y. performed the genome assembly; ...the genome annotation; X.X. and his team performed the whole-genome amplification step; ...the ...
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Whole-genome haplotyping approaches and genomic medicine
... first whole-genome sequenced family [64], but such analyses have been routine for years in the analysis of candidate genes, such as those for cystic fibrosis and breast cancer ...
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Whole genome sequence analysis of Mycobacterium suricattae
... Dippenaar, A, Parsons, S D C, Sampson, S L, van der Merwe, R G, Drewe, J A, Abdallah, A M, Siame, K K, van Pittius, N C G, van Helden, P D, Pain, A and Warren, R M (2015) Whole genome sequence analysis of ...
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Ranks of Genuine Associations in Whole-Genome Scans
... which genome scans produced true associations ranking at the beginning of the ...the whole-genome ...hand, whole-genome scans with ...
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Whole genome phylogenies for multiple Drosophila species
... when whole genome sequences are available, is to employ methods that don ’ t use explicit sequence ...within whole genomes without the prior identification of orthologs or homologous ...the ...
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Whole genome prediction for preimplantation genetic diagnosis
... The whole genome sequence of the embryo was pre- dicted by combining PS embryo genotypes with parental haplotype blocks (Additional file 1: Figures S3, S4, and ...entire genome for both the mother ...
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What’s in a Name? Species Wide Whole Genome Sequencing Resolves Invasive and Noninvasive Lineages of Salmonella enterica Serotype Paratyphi B
... core genome size of isolates sharing the Paratyphi B serotype (2,949 genes) is smaller by almost 1,000 genes than those reported for other serotypes, such as ...core genome across the sample data set, ...
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Ethical and legal implications of whole genome and whole exome sequencing in African populations
... technologies in human research will be important on the continent of Africa, especially since there is a need to improve genetic literacy in sub-Saharan Africa [92]. Workshops for training members of IRBs/RECs as well as ...
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Whole Genome Sequencing of Invasion Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion
... cells. Whole-genome sequencing and transcriptome sequencing (RNA-Seq) uncovered a deletion in the gene encoding the laminin subunit ␣ 2 (Lama2) that eliminated much of domain ...
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On the Ethics of Clinical Whole Genome Sequencing of Children
... apply whole exome sequencing (WES) to diagnose a pediatric patient with a rare digestive ...include whole genome sequencing (WGS) and has since re- ceived requests from around the world to perform ...
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Whole Genome Mapping as a Novel High Resolution Typing Tool for Legionella pneumophila
... called whole-ge- nome mapping (WGM) has recently been used as a high-resolu- tion typing technique ...ordered, whole-genome restriction maps for comparative ...
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Targeted or whole genome sequencing of formalin fixed tissue samples: potential applications in cancer genomics
... Performing sequencing analyses using DNA isolated from FFPE samples is technically challenging. DNA extracted from FFPE blocks is highly variable due to DNA damage introduced by the fixation process. Formalin fixation ...
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