[PDF] Top 20 1 Mitochondrial dynamics in stem cells and

... mitochondrial outer membrane (MOM) fusion, mediated by mitofusin proteins (Mfn1 and Mfn2) 48.. [13-17] and mitochondrial inner membrane (MIM) fusion, mediated by Opa1, and could be poss[r] ... See full document

... 5 Mitochondrial transfer from MSCs to NSCs damaged by cisplatin restores mitochondrial membrane ...Neuronal stem cells (NSCs) were treated with vehicle or 1 μ M cisplatin for 8 h, ... See full document

... to 1% of the population [42,43]. The origins, implications and dynamics of these observations have been discussed elsewhere ...the stem cell pool (Figure  ... See full document

... the mitochondrial genome) and partial deficiency of subunit IV (encoded by the nuclear ...the mitochondrial or nuclear ...a mitochondrial and nuclear gene involvement ... See full document

... Other cells such as fibroblast and somatic cells have also shown the ability to transfer ...mitochondria. Mitochondrial donation by MSCs is a faster and more economical physiological process in the ... See full document

... as mitochondrial OGT (mOGT) has nine TPRs and a mitochondrial targeting sequence at its N-terminus, and finally a short isoform (sOGT) with only two TPRs (Lazarus et ...of mitochondrial proteins ... See full document

... the cells started to detach from culture dish, and these cells were mostly verified ...PC3 cells in this medium were heterogeneous, and when the cells gradually lose their mtDNA content, only ... See full document

... HeLa cells, being consistent with a mitochondria-perturbing mode of ...treated cells suggests that the natural product targets a pathway that is critical for oxidative ...to mitochondrial ... See full document

... mtDNA, cells become heteroplasmic containing two types of mtDNA which are randomly segregated at mitosis, resulting in genetic drift towards mutated or wild type ...daughter cells, different phenotypes are ... See full document

... T cells co-cultured with BM-MSCs To determine whether mitochondria are transferred from BM-MSCs into primary lymphocytes, BM-MSCs were labeled with the MitoTracker Green probe and co- cultured with human PBMCs ... See full document

... in mitochondrial release from stem cells The first step of mitochondrial transfer is the release of mitochondria from donor ...that mitochondrial Rho-GTPase 1 (Miro1) may be ... See full document

... about stem cell regulation in many tissues has been gathered by culturing stem cells under various conditions and studying their ...about 1-2% of germ cells in culture can give rise to ... See full document

... Successful mitochondrial fusion also requires coordination of the fusion of outer and inner membranes, which are biochemically ...wild-type cells (Hermann, Thatcher et ...as cells cultured from the ... See full document

... ‘retinal stem cells’ to designate cells that are a source of postnatal or adult retinogenesis (Table ...of stem cells, ...‘retinal stem cells’ should only be employed ... See full document

... in mitochondrial respiratory chain function underlie a spectrum of human diseases, ranging from impairment in cellular metabolisms and ageing (Semenza ...(Figure 1). It is well known that cells in ... See full document

... 7RGHWHUPLQHWKHUROHRI+,)_ in proliferation, survival and dopaminergic differentiation in vitro, as well as survival of murine dopaminergic neurons in vivo+,)_ was conditionally inactivated ... See full document

... glial cells in the ventricular zone (VZ) differentiate asymmetrically to generate mature neurons directly targeting additional neuronal divisions [60, ...meningeal cells secreting the stromal cell-derived ... See full document

... MI-mediated mitochondrial function by changing the expression of mitochondrial dynamics and mitophagy proteins, which the role of intermediate intensity training was more ...improved ... See full document

... transcriptional activity of TEAD, the transcriptional co- activators of Hippo signaling pathway, was the most highly regulated by upregulation of TFAP2C, but si- lenced by downregulation of TFAP2C in CRC cells ... See full document

... progenitor cells, signaling molecules and matrix scaffold in an orderly temporal and spatial ...transplanted cells to survive and function. To summarize, the promise of stem cell therapies is an ... See full document