[PDF] Top 20 Activity-based protein profiling
Has 10000 "Activity-based protein profiling" found on our website. Below are the top 20 most common "Activity-based protein profiling".
Activity-based protein profiling
... Activity-based protein profiling is a method to study a subset of the enzymatically active pro- ...efficiency. Activity-based protein profiling has well-developed applications in ... See full document
10
Activity-based protein profiling and labeling of bacterial monooxygenase enzymes.
... The role bacterial monooxygenase enzymes play in the degradation of polluting substances has long been recognized. While much is known about how these enzymes contribute to contaminant biodegradation, there are currently ... See full document
221
Activity-based protein profiling guided identification of urine proteinase 3 activity in subclinical rejection after renal transplantation
... a protein does not necessarily imply functional ...methods based on mass spectrometry or immunoassays generally do not provide information on the functional status of ...of activity-based ... See full document
14
Activity-Based Protein Profiling of Alkane-Oxidizing Monooxygenases in Rhodococcus rhodochrous ATCC 21198.
... An activity-based protein profiling (ABPP) method was developed to identify and characterize the gaseous alkane-oxidizing monooxygenases in this ... See full document
95
In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity-based protein profiling
... substrates, activity-based probes (ABPs) could be superior tools for this ...competitive activity-based protein profiling (ABPP) approach to identify in vivo target engagement of ... See full document
18
The use of activity based protein profiling to study proteasome biology
... termed activity based protein profiling (ABPP) ...called activity-based probes (ABPs), which create a covalent and irreversible bond with the catalytic active site of the enzyme ... See full document
92
Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474
... used activity- based protein profiling (ABPP), a chemical proteomic method that employs active site- directed chemical probes ...cellular activity of BIA 10-2474 is unclear, but could ... See full document
11
Multiplex Fluorescent, Activity-Based Protein Profiling Identifies Active α-Glycosidases and Other Hydrolases in Plants
... dedicated protein database by translating the publicly available RNA sequencing data from Jain et ...the protein N terminus (42 D) as dynamic modifications and the static modi- fication of Cys (57 D, ... See full document
14
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe
... Subconfluent cells (80-90%) were washed and pooled with ice-cold 10 mM sodium phosphate buffer, pH 7. The cells were then subjected to Dounce-homogeniza- tion at 30% power (T8 Ika-Werke homogenizer, GMBH, Staufen, ... See full document
15
From medicinal chemistry optimisation of antimalarial 2-aryl quinolones to synthesis and application of endoperoxide activity-based protein profiling probes
... Shortly after the discovery of SL-2-25 (55), it became evident that the physico-chemical properties of this lead needed to be improved 1 . The poor aqueous solubility of 55 impacts on the pharmacokinetic profile by ... See full document
223
Advancing understanding of microbial bioenergy conversion processes by activity-based protein profiling
... Over the past few years, ABPP has boomed in the field of chemical biology through elucidation of target func- tional proteins in vivo and in vitro. ABPP techniques that integrate transcriptomics, proteomics, fluorescence ... See full document
15
Development of a Multiplexed Activity-Based Protein Profiling Assay to Evaluate Activity of Endocannabinoid Hydrolase Inhibitors
... the activity and selectivity of compounds inhibiting biosynthetic or metabolic enzymes of the ...ed based on previous ...inhibitory activity of LEI104 on DAGL- α and FAAH in this new multiplexed ABPP ... See full document
8
Direct and two-step activity-based profiling of proteases and glycosidases
... ´activity-based protein profiling´ (ABPP), een vakgebied binnen de chemische biologie met als doel de activiteit van enzymen zichtbaar te maken en te kwantificeren in de context van een ... See full document
168
Evaluation of clinical colon carcinoma using activity-based proteomic profiling
... FAP’s activity by either immunocapturing FAP from a cellular lysate prior to adding a fluorogenic substrate (16), or by measuring FAP’s abil- ity to degrade 3H-gelatin ...FAP activity in patients with more ... See full document
11
Protein expression profiling during chick retinal maturation: a proteomics-based approach
... positive protein identifica- tion the matched peptides were always related back to the raw spectra to check the matched peptides were the most intense peaks in the ...weight based on the spot's position ... See full document
11
A comparison between protein profiles of B cell subpopulations and mantle cell lymphoma cells
... Proteomic profiling using liquid chromatography-MS/MS has been applied to a limited number of lymphomas of different origin ...is based on chip-binding of intact proteins and endog- enous peptides, has been ... See full document
8
Original Article Protein profiling detection in serum of silica-exposed population by liquid-chip time of flight mass spectrometry
... Abstract: Objective: To screen serum biomarkers of silica-exposed population for early diagnosis by liquid-chip time of flight mass spectrometry, and identify some associated functions of the markers. Methods: In ... See full document
10
Profiling protein ubiquitination in Arabidopsis thaliana
... the protein (discussed in [44]). While the PEG-based procedure was effective at depleting approximately 85% of RuBisCO, the protocol required a short incubation at high temperatures which raised concerns ... See full document
295
Kinase Activity Profiling of Gram-Negative Pneumonia
... Kinase activity arrays enable the analysis of 1,024 con- sensus sequences of protein kinase ...kinase activity array on whole lung lysates, cellular kinase activities were determined in a mouse model ... See full document
7
SHORT COMMUNICATION MOLECULAR ANALYSIS OF MAIZE HYBRIDS AND THEIR PARENTS USING ISSR AND PROTEIN PROFILING
... and protein profiling on SDS-PAGE were employed to assess genetic diversity in four maize hybrids and their ...ISSR profiling similarity matrix was obtained using Jaccard Similarity Coefficient was ... See full document
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