[PDF] Top 20 Analysis of Netrin 1 receptors during inner ear development
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Analysis of Netrin 1 receptors during inner ear development
... Ntn1 receptors are missing (Neo1-/- mammary glands) or functionally blocked (integrins in pancreatic cell cultures) (Srinivasan et ...observed during Ntn1-/- inner ear development and ... See full document
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Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice
... Hearing in mice was assessed by auditory-evoked brain stem response (ABR) threshold analysis. Mice were anesthetized with an intraperitoneal injection of tribromoethanol (0.2 ml of 20 mg/ml stock per 10 g of body ... See full document
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Cell proliferation during the early compartmentalization of the Xenopus laevis inner ear
... S47 inner ear ...of inner ear development and raise questions about underlying mecha- nisms, such as the contribution of apoptotic events to develop- ment of the ...laevis inner ... See full document
9
Genetic and epigenetic alterations of netrin-1 receptors in gastric cancer with chromosomal instability
... We collected tissue specimens of primary gastric cancer and matched normal gastric mucosa from 105 patients who had undergone surgery at the Okayama University Hospital (Okayama, Japan). Of 105 gastric cancer patients, ... See full document
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Discovering Novel Hearing Loss Genes: Roles For Esrp1 And Gas2 In Inner Ear Development And Auditory Function
... deficient inner ears and discovered a cohort of cochlear enriched ...and development, such as Gata3, Pax2, and ...cochlear development, and provide intriguing potential candidates for follow-up ... See full document
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CHD7 represses the retinoic acid synthesis enzyme ALDH1A3 during inner ear development
... Analysis of CHD7 and RAR localization in mouse ESCs. DNA sequences associated with CHD7 and RAR were compared with determine commonly bound regions within the mouse ESC genome. CHD7 ChIP- seq reads were obtained ... See full document
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Expression of netrin-1 receptors in retina of oxygen-induced retinopathy in mice
... blot analysis of the netrin-1 receptor protein For biochemical studies, the eyeballs were removed after neck dislocation on P12, P17, and P21, and the animals with weight >6 g were ... See full document
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From shared lineage to distinct functions: the development of the inner ear and epibranchial placodes
... The inner ear also gives rise to neurons, and, like the epibranchial placodes, inner ear neuroblasts delaminate from the epithelium and coalesce to form ...of inner ear neurons, ... See full document
9
Establishment of a proneural field in the inner ear
... initial development of this domain is regu- lated by Notch signaling like in Drosophila, suggesting a classical proneural role of atoh1b in zebrafish (Millimaki et ...changes during this ...cells, ... See full document
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Single cell analysis of the inner ear sensory organs
... Pax2-driven EGFP expressing cells to obtain a purified otocyst and delaminating neuroblast cells versus non-otic surrounding cells in the embryonic day (E)10.5 developing mouse embryo (Hartman et al., 2015) . The use of ... See full document
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Temporal and spatial expression patterns of Hedgehog receptors in the developing inner and middle ear
... mammalian inner ear is a complex organ responsible for balance and ...of inner ear development, including dorsoventral axial specification, cochlear elongation, tonotopic patterning, ... See full document
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Original Article Neuron-derived netrin-1 and netrin-4 proteins are additional effective targets in diabetic retinopathy beyond VEGF
... of netrin-1 and net- rin-4, we injected exogenous abundant net- rin-1 and netrin-4 into the vitreous of diabetic rats, and the results showed both of them can reduce retinal vascular ...of ... See full document
15
Patterning and morphogenesis of the vertebrate inner ear
... 1997). Inner ear analyses of Pax2-/- mutants reveal an early requirement of Pax2 in cochlear duct outgrowth (Torres et ...Pax2-/- inner ears indicate that the cochlear outgrowth and patterning is ... See full document
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Cross repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear
... idea is that the main function of Lrig3 is to restrict expression of Ntn1 to the fusion plate. As hypothesized, we found that Ntn1 expression is expanded to encompass the entire lateral pouch epithelium in Lrig3 mutants ... See full document
9
The development of semicircular canals in the inner ear: role of FGFs in sensory cristae
... FGF receptors (Ornitz et ...canal development were ...the inner ear at E4-E5 under standard conditions (see Materials and methods) interferes with common crus formation by E9 ...Table ... See full document
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Absent Semicircular Canals in CHARGE Syndrome: Radiologic Spectrum of Findings
... stapedius muscles in all cases. This is not surprising given that the ossicular abnormalities in the CHARGE syndrome (gen- erally of the long process of the incus and the stapes) seem to result primarily from a defective ... See full document
9
Limited inner ear morphogenesis and neurosensory development are possible in the absence of GATA3
... the development of an empty otocyst with an endolymphatic ...neurosensory development is possible in the ear without ...mutant inner ears can undergo partial morphogenesis and develop an ... See full document
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Mouse models to study inner ear development and hereditary hearing loss
... Usher syndrome is the most common etiology for a combina- tion of hereditary deafness and blindness. This disease combines congenital sensorineural hearing loss and a progressive loss of the visual field due to retinitis ... See full document
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Delta like 1 and lateral inhibition during hair cell formation in the chicken inner ear: evidence against cis inhibition
... To investigate the spatiotemporal pattern of Notch activity during chicken inner ear development, we used a reporter of Notch activity that contains a 0.8 kb fragment of the promoter of the ... See full document
11
Sculpting the labyrinth: Morphogenesis of the developing inner ear.
... One hypothesis that has attracted much attention over the last decade posits that formation of the non-sensory canal ducts is dependent on signalling from the developing sensory cristae to establish a ‘canal genesis ... See full document
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