[PDF] Top 20 Antigen processing and T cell priming by mouse dendritic cells
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Antigen processing and T cell priming by mouse dendritic cells
... the T cell repertoire for HEL in these mice was then ...a T cell response to the normally dominant determinant (in non-HEL transgenic H-2^ mice) HEL ...because T cells specific ... See full document
216
Utilisation of an in vitro T-cell priming assay to characterise the effects of co-inhibitory signalling on the activation of antigen-specific T-cells.
... activate T-cells by a non- covalent, reversible interaction directly with the TCR or ...an antigen receptor, whether this be the TCR, MHC, or both to stimulate a T-cell response ... See full document
333
Immunosuppressive effects of radiation on human dendritic cells: reduced IL-12 production on activation and impairment of naïve T-cell priming
... nullify antigen-specific immune responses (Melcher et al, ...Alternatively, antigen- loaded DC can be used ex vivo to expand specific effector T-cell populations for subsequent adoptive ... See full document
9
Plasmacytoid dendritic cells induce NK cell–dependent, tumor antigen–specific T cell cross priming and tumor regression in mice
... NK cell tumor infiltration at treat- ment day 2, as determined by ...NK cells. (C) Tumor infiltration by CD8 + T cells at treatment day ... See full document
12
Three day dendritic cells for vaccine development: Antigen uptake, processing and presentation
... Next, we analyzed protein expression in 3d and 7d mDC after electroporation of ivtRNA, alongside their sti- mulatory capacity for CTL. As shown previously, anti- gen-loaded fast DC were clearly able to stimulate T ... See full document
13
Effective Priming of Herpes Simplex Virus-Specific CD8+ T Cells In Vivo Does Not Require Infected Dendritic Cells
... new mouse model in which virus-infected DC could be ...infected cells would produce Cre, transcribe DTX, and consequently ...certain cell types, such as DC (27, ...of cells in the DRG ... See full document
13
Nicotine Protects Dendritic Cells from Apoptosis and Support DCs-dependent CD4+ T-cell Priming in vitro
... C57BL/6 mouse was ...70-µm cell strainer. Red cells were depleted using 1 ml red cell lysis buffer for 2 min at room ...temperature. Cells were washed with PBS. Then, the cells ... See full document
11
Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells
... and T cells in intact lymph nodes ...DO11.10 T cells and were subsequently immunised subcutaneously with CFSE-labelled ...these cells had migrated to the draining LN and could be seen ... See full document
8
Expression of vFLIP in a Lentiviral Vaccine Vector Activates NF-κB, Matures Dendritic Cells, and Increases CD8+ T-Cell Responses
... to dendritic cells (DCs) in vivo, but they do not trigger DC ...in mouse bone marrow-derived DCs in vitro and matured these DCs to a similar extent as lipopolysaccharide; costimulatory markers CD80, ... See full document
8
Functional characterization of biodegradable nanoparticles as antigen delivery system
... professional antigen- presenting cells (APCs), such as dendritic cells ...and mouse Hepa 1 – 6 hepatoma cell ...the cells, they formed multivesicular endosomes ...vivo ... See full document
13
Production Large Array of Cytokines by Mouse Dendritic Cells Pulsed with Hepatitis C Virus Pseudo-particles
... cycle. Dendritic cells (DC), the most potent antigen presenting cells (APC) found at trace levels in lymphoid and nonlymphoid tissues, are required for the priming of naive T ... See full document
10
Cells of the synovium in rheumatoid arthritis Dendritic cells
... autoreactive T cells into the periphery, where subsequent genetic or environmental proinflammatory events more readily trigger the priming of these T cells and the development of ... See full document
12
Dendritic Cell Migration Limits the Duration of CD8+ T-Cell Priming to Peripheral Viral Antigen
... viral antigen is expressed at physiologically relevant levels in the periphery in somatic cells but not within ...the T CD8 ⫹ response to peripheral antigen was insufficient to clear ... See full document
9
Enhanced presentation of MHC class Ia, Ib and class II restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy
... murine dendritic cells (DC) with the peptide-containing nanoparticles and determined their ability to present the encapsulated peptide antigens and to induce tumor-specific cytotoxic T lymphocytes ... See full document
10
The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigen-specific T cells
... The IDO1 enzyme inhibitor epacadostat represents a new class of inhibitor, a hydroxyamidine small molecule, which potently inhibits IDO1 function without affecting IDO2 and TDO. It has been very well tolerated in ... See full document
11
Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients
... + T cell and NK cell infiltration by IHC ...+ T cells in PT samples from CALR Hi patients as compared to the their CALR Lo counterparts ( p = ...NK cells in PT ...+ T ... See full document
12
Novel 89Zr cell labeling approach for PET-based cell trafficking studies
... a cell labeling reagent for PET- based cell ...the cells post-labeling commonly associated with oxine-based ...myeloma cells (from 93% to ...radiolabeled cells over the first 24 h, ... See full document
11
Induction of CD4+ T cell–dependent antitumor immunity by TAT mediated tumor antigen delivery into dendritic cells
... into cells at 4°C and are independent of receptor- or endosome-mediated endocytosis ...many T cell peptides, including MHC class I– and class II– restricted peptides, are known, delivery of these ... See full document
9
Allergic sensitization: host-immune factors
... epithelial cells from asthmatic subjects are more sensitive to environmental triggers including cigarette smoke [11] and viruses [12] in terms of both barrier disruption and an innate defect in the release of ...a ... See full document
9
Human and murine dermis contain dendritic cells Isolation by means of a novel method and phenotypical and functional characterization
... Langerhans cell of the epidermis is used as a prototype for studies of DC in the ...these cells in nonlymphoid organs other than ...dermal cells have the following key features of mature DC: (a) ... See full document
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