[PDF] Top 20 Cancer subtypes classification using long non-coding RNA
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Cancer subtypes classification using long non-coding RNA
... different subtypes of cancer: ovarian, prostatic, lung SCC and glioma ...genomic classification in ovarian cancer, glioma, and lung squamous cell ...ovarian cancer, unsupervised lncRNAs ... See full document
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Original Article Macrophage infiltration promotes invasiveness of breast cancer cells via activating long non-coding RNA UCA1
... We recognize, however, that our approach has several limitations. First, given the complexity of the signals in microenvironment in determin- ing macrophage subtype and function, a mixed phenotype-expressing macrophage ... See full document
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CRNDE: an oncogenic long non-coding RNA in cancers
... Epithelial-mesenchymal transition (EMT) has been recognized as a critical biological process in cancer metastasis. The expanding knowledge relating to EMT has clarified the EMT programme as a set of dynamic ... See full document
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Original Article A novel long noncoding RNA IRAIN regulates cell proliferation in non small cell lung cancer
... IRAIN in NSCLC tissues and explored its role in NSCLC development and progression in vitro primarily. We discovered that IRAIN was increased in NSCLC tissues and identified the upregulated expression of IRAIN in bigger ... See full document
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The functional role of long non-coding RNAs and epigenetics
... (HOTAIR long ncRNA) is able to promote cancer metastasis by inducing epigen- etic variations in the chromatin state of cancer cells ...of non-coding RNAs in chromatin formation has also ... See full document
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Identification of long non-coding RNA signatures in triple-negative breast cancer
... years, long non-coding RNAs (lncRNAs) have drawn an increased attention because of their functions in the human diseases including ...of RNA transcripts with a length of > 200 nucleo- tides ... See full document
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Original Article Long noncoding RNA ZEB1-AS1 predicts an unfavorable prognosis of non-small lung cancer and regulates epithelial to mesenchymal transition through reducing ZEB1 expression
... Abstract: Long non-coding RNAs (lncRNAs) are critical gene regulators with important roles in a wide variety of bio- logical processes, including ... See full document
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Original Article Long-chain non-coding RNA HOTAIR expression in tissue samples correlates with gastric cancer survival
... The results of this study have shown that patients with higher HOTAIR expression level have shorter OS and PFS, and poorer progno- sis, and that HOTAIR expression level, together with biological behavior of tumors and ... See full document
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The lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer
... for cancer is lung cancer, of which the majority sub- type is non-small cell lung cancer ...shown long non-coding RNAs are transcribed and contribute to ...endogenous ... See full document
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<p>Latest Advances of Long Non-Coding RNA SNHG5 in Human Cancers</p>
... of non-coding RNAs (ncRNAs) is up to ...of long non-coding RNAs (lncRNAs), microRNAs (miRNAs), small interfering RNAs (siRNAs), transfer RNAs (tRNAs), ribosomal RNAs (rRNAs), small ... See full document
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A Long Non-coding RNA Lnc712 Regulates Breast Cancer Cell Proliferation
... factors using pull-down assays. Biotinylated Lnc712 (or a negative control RNA) was incubated with total protein extracts from MCF-7/ADM cells and pulled down with streptavidin beads to identify the ... See full document
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Ultraconserved Long Non-Coding RNA Uc.112 is Abnormally Expressed in Childhood Acute Lymphoblastic Leukemia Subtypes
... Using bioinformatics approaches [9], we evaluated potential regulatory elements associated with uc.112 genomic position. Uc.112 region was bound with the transcription factors NFIC, ATF2, MAZ, SP1, TBL1XR1, ... See full document
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A four-long non-coding RNA signature in predicting breast cancer survival
... By using the same cut-off value as the training set, the patients from each testing set were separately classified into low- risk and high-risk groups and subjected to survival com- ... See full document
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MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
... of cancer cell lines [41]; moreover, p53 may also repress the promoter of the H19 lncRNA [42], a maternally imprinted gene overexpressed in fetal tissues and silenced after birth, initially described as tumor ... See full document
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Prognostic and predictive values of long non-coding RNA LINC00472 in breast cancer
... Our clinical study showed that LINC00472 expression was significantly different by tumor grade, tumor size, disease stage, receptor status and molecular subtype. The expression was also associated with treatment response ... See full document
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The Roles and Diagnostic Potential of Long Non-Coding RNAs in Some Cancers: A Review
... Urothelial carcinoma-associated 1 (UCA1) lncRNA is a BC-related oncogene that can directly interact with miR-143, a tumor suppressor in BC, and regulate proliferation and apoptosis of cancer cells. In this line, ... See full document
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Long non-coding RNA: a new player in cancer
... bladder cancer cell in vitro and in vivo, indicating lncRNA CUDR func- tions as an oncogene and may serve as a novel therapeutic target for bladder cancer ... See full document
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Long non-coding RNA UCA1 is a predictive biomarker of cancer
... in cancer prognosis and the acquired resistance to drugs ...advanced non-small cell lung cancer (NSCLC) that harbor mutations that activate epidermal growth factor receptor (EGFR) can be treated with ... See full document
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Enhanced expression of long non coding RNA NEAT1 is associated with the progression of gastric adenocarcinomas
... TN classification system and graded into five groups: stage 0 (TisN0M0, n = 0), stage 1 (T1N0–1M0, n = 4), stage 2 (T1N2M0, T2N0–1M0, n = 30), stage 3 (T2N2M0, T3N1–2M0, T4N0M0, n = 66), stage 4 (T4N1–2M0,T1– ... See full document
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Original Article Long non-coding RNA ANRIL promotes tumorigenesis in glioma via MAPK signaling pathways
... To further define the underlying molecular mechanism modulated by ANRIL in the growth of glioma cells, we focused on the Mitogen- activated protein kinase (MAPK) pathway, which including extracellular signal-regulated ... See full document
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