[PDF] Top 20 From disease to development to cell biology and back

... Although the concept of the morphogen has pervaded studies of morphogenesis, little is known about how morphogen gradients actually form. Previous theories have suggested that morphogens spread across tissues by freely ... See full document

... impact development, homeostasis, and ...and cell-level forces or mechanical properties, and so the mathematics of mechanotransduction becomes important to ...heart development where cardiac ... See full document

... the development of a network of abnormal collateral ...moyamoya disease corresponds to isolated moyamoya angiopathy, defined as being “idiopathic” according to the Guidelines of the Research Committee on ... See full document

... Abstract: Oxygen represents one of the major molecules required for the development and maintenance of life. An adequate response to hypoxia is therefore required for the functioning of the majority of living ... See full document

... inflammatory disease of the arterial walls that often leads to myocardial infarction and/or ...subsequent development of atherosclerotic lesions in ...the development of novel treatment strategies to ... See full document

... However, the huge controversial discussion comes up with the hypothesis that hepatocytes and cholangiocytes would be liver progenitors cells per se when undergoing transdifferentiation from one cell type to ... See full document

... the development of severely aneuploid embryonic cells and embryonic lethality (Schumacher et ...one cell stage (Schumacher et ...evidence from a variety of organisms supports that ... See full document

... the development of risk factor ...chronic disease agenda and provided specific opportunities to put them into ...policy development at the local level across settings that are often dealt with ... See full document

... to cell death ...tumor cell death either driven by the formation of lethal DSBs or because mutagenic forms of repair predominate in the absence of ...vitro cell culture. Clonogenic assays, which ... See full document

... ABSTRACT The career of Marc Mareel is a synthesis of scientific research and clinical activity. Dur- ing his medical studies, he already made his first enthusiastic steps in research via experimental work on avian ... See full document

... Abstract: Improved understanding of interactions between nanoparticles and biological systems is needed to develop safety standards and to design new generations of nanomaterials. This article reviews the molecular ... See full document

... a cell depend on multiple signals rather than just one: by using signals in combinations an animal can control the survival of its cells in specific ways using a relatively small number of ... See full document

... of development is found in two traditionally defined orders of nemerteans - the monophyletic Hoplonemertea, and the basal (and, possibly, paraphyletic) Palaeonemertea (Maslakova ...and development of the ... See full document

... the development of the foetus: the inferior or mucous membrane deals with the formation of intestine, just as the vascular membrane contains the heart and the vessels and the serous membrane represents the ... See full document

... technological development. A precondition is an essential development condition that needs to be m et for the d e v elo p m en t to be successfu lly ...y development to ...technological ... See full document

... the cell as inactive precursors, procaspases, which are, usually, activated via proteolytic cleavage by another member of the caspase family, forming an amplifying proteolytic ... See full document

... embryonic cell cycle differs from the subsequent ...first cell cycle relies on maternal factors ...transcribed from embryonic genome is detectable in G2 phase of the first cell cycle ... See full document

... Cnidarians were an obvious group on which to test the hypothesis that there was a set of so called “zootype genes”, common to all animals, which were expressed in a characteristic order along the anterior/posterior (A/P) ... See full document

... Th e other option is the Brazilian model, which can serve to promote the protection of forests and the growth of agriculture. While the model was imperfectly applied in the beginning, the Brazilian government sub- ... See full document

... Int I I) ,' Riol ~O 653 659 (19961 653 Primordial germ cell development is the urodele pattern closer to mammals than to anurans? MASAMI WAKAHARA* Biological Sciences, Graduate School of Science Hokka[.] ... See full document