[PDF] Top 20 Distinct gene expression profiles of human type 1 and type 2 T helper cells
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Distinct gene expression profiles of human type 1 and type 2 T helper cells
... study gene expression on a large scale [4,5]. The expression of a large number of genes can be monitored simultaneously and the expression profiles in different samples ...the ... See full document
11
CD27 expression discriminates porcine T helper cells with functionally distinct properties
... - T helper cells have functional similar- ities towards central (high proliferation capacity) and effector (rapid production of effector cytokines) memory T cells, respectively, as ... See full document
14
Activation of Human T-Cell Leukemia Virus Type 1tax Gene Expression in Chronically Infected T Cells
... HTLV-1 gene expression, we have utilized a series of HTLV-1 chronically infected cell lines exhibiting differing levels of ex- pression of HTLV-1 proteins (17, ...1657 cells ... See full document
7
Transient Mobilization of Human Immunodeficiency Virus (HIV)-Specific CD4 T-Helper Cells Fails To Control Virus Rebounds during Intermittent Antiretroviral Therapy in Chronic HIV Type 1 Infection
... in human immunodeficiency virus (HIV)-infected patients (1, 10, ...HIV-specific T-cell im- ...CD8 T-cell responses also depend on generating or maintaining high levels of HIV- specific CD4 Th1 ... See full document
8
SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses
... marker expression was assessed by flow cytometry using anti-CD3 (BD), anti-CD4 (BD), or anti-CD8 ...staining, cells were restimulated in complete medium at 37°C for 4 h with 50 ng/ml PMA (Sigma-Aldrich), ... See full document
9
Epidermal Growth Factor Receptor Expression Licenses Type 2 Helper T Cells to Function in a T Cell Receptor Independent Fashion
... resting T cells, donor mice were infected with ...and T cells were enriched as described ...memory T cells were generated with nebulised ...or 1 month following the last ... See full document
20
Costimulation of cytokine gene expression in T cells by the human T leukemia/lymphotropic virus type 1 trans activator Tax.
... of T cells through their antigen-specific T-cell receptor results in the coordinate expression of a number of cytokine genes such as interleukin-2 (IL-2), IL-3, granulocyte- ... See full document
8
Adenoviruses Activate Human Dendritic Cells without Polarization toward a T-Helper Type 1-Inducing Subset
... whereas expression of the viral genome at high MOI is not strictly dependent on a functional E1 protein, we tested whether the presence or absence of the different early regions affected rAd-induced DC ...the ... See full document
9
Human Immunodeficiency Virus Type 1 (HIV-1) Vpr Functions as an Immediate-Early Protein during HIV-1 Infection
... directed gene expression was shown to lead to an increase in viral ...Tat expression, stimulated Tat ...CAT gene expression. Jurkat T cells transfected with pCEP4III ... See full document
9
Induction of Lactoferrin Gene Expression in Myeloid or Mammary Gland Cells by Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax: Implications for Milk-Borne Transmission of HTLV-1
... upregulated expression of lactoferrin, a major constit- uent in these body ...neighboring cells in a paracrine ...lactoferrin-producing cells, such as neutrophils and mammary epithelial cells, ... See full document
9
Early Induction and Maintenance of Env-Specific T-Helper Cells following Human Immunodeficiency Virus Type 1 Infection
... and T-cell ...After 2 min of incubation at 50°C and 2 min of denaturation at 95°C, 45 cycles (95°C for 20 s and 60°C for 60 s) of amplification were ...standard, human placental DNA (Sigma) ... See full document
12
Expression of intelectin-1 in bronchial epithelial cells of asthma is correlated with T-helper 2 (Type-2) related parameters and its function
... goblet cells, pri- marily from fetal small ...its expression and role in human asthmatic airways is poorly ...attracts T-helper (Th)1 cells [20] and strongly induced by ... See full document
11
Follicular helper T cell signature in type 1 diabetes
... sufficient cells of each type, cells from 14 mice were pooled to generate each ...Sorted cells were snap frozen immediately in liquid nitrogen, and RNA was sub- sequently extracted using the ... See full document
13
Transforming growth factors beta 1 and 2 transcriptionally regulate human papillomavirus (HPV) type 16 early gene expression in HPV-immortalized human genital epithelial cells.
... 10 Transforming Growth Factors Beta 1 and 2 Transcriptionally Regulate Human Papillomavirus HPV Type 16 Early Gene Expression in HPV-Immortalized Human Genital Epithelial Cells C.. DiPAO[r] ... See full document
9
Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report
... thelial cells and migrate into the surrounding tissue in order to phagocytose and degrade immune complexes ...and expression of surface endothelial adhesion molecules ...myeloma cells that also ... See full document
6
The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse model
... marrow cells had higher in vitro proliferation capacities as shown by more colonies in cobblestone-area forming assays and by serial re-plating ...hematopoietic cells from Asxl1 tm/+ mice declined faster in ... See full document
15
Productive and lytic infection of human CD4+ type 1 helper T cells with macrophage-tropic human immunodeficiency virus type 1.
... Th0 cells produce both Th1- and Th2-type ...HIV- 1-infected individuals does not occur at the clonal CD4 1 T-cell level; instead, they have suggested that a shift from Th1 to Th0 occurs ... See full document
6
A detailed phenotypic analysis of immune cell populations in the bronchoalveolar lavage fluid of atopic asthmatics after segmental allergen challenge
... containing 1% BSA and incubated with anti- bodies directed against the following cell subsets: T cells were identified as CD4 or CD8, as naïve (CD45RA) or memory (CD45RO), and surface phenotyped for ... See full document
8
The role of IFN gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity
... that T cells could be conveniently divided into two main subsets, ie Th1 and Th2, with distinct arrays of cytokine secretion patterns and functions ... See full document
6
Dimerization and a Novel Tax Speckled Structure Localization Signal Are Required for Tax Nuclear Localization
... Efficient expression of Tax deletion mutants is comparable to that of wild-type ...293 T cells transfected with the appropriate plasmids for expression of the indicated ...protein ... See full document
14
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