[PDF] Top 20 V Domain of Human SLAM (CDw150) Is Essential for Its Function as a Measles Virus Receptor
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V Domain of Human SLAM (CDw150) Is Essential for Its Function as a Measles Virus Receptor
... of SLAM with A12 or IPO-3 induces activation and proliferation of T and B cells (3, 7, 22, 34), SLAM must interact with its natural ligand also through the V ...the V domain of ... See full document
7
Identification of a cytoplasmic Tyr-X-X-Leu motif essential for down regulation of the human cell receptor CD46 in persistent measles virus infection.
... for receptor down regulation in persistent infection by paramyxovirus has been suggested in the human parainflu- enza virus type 3, which maintains a noncytopathic infection by removing neuraminic ... See full document
5
High Pathogenicity of Wild-Type Measles Virus Infection in CD150 (SLAM) Transgenic Mice
... expressing human CD150 (SLAM), the receptor for both wild-type and vaccine MV ...first SLAM transgenic model where MV infection induces a severe pathogenic ...of human SLAM in ... See full document
10
The Second Extracellular Loop of CXCR4 Determines Its Function as a Receptor for Feline Immunodeficiency Virus
... corresponding domain of CXCR2 (chimeras 2442, 2242, 4442, and 2244) failed to sup- port cell fusion mediated by ...of function as a receptor for FIV, the adja- cent loops either maintain the second ... See full document
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The Receptor Attachment Function of Measles Virus Hemagglutinin Can Be Replaced with an Autonomous Protein That Binds Her2/neu While Maintaining Its Fusion-Helper Function
... the virus receptor followed by fusion between the virus and host cell ...membranes. Measles virus (MV) attachment to its receptor is mediated by the hemagglutinin (H), ... See full document
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Measles Virus Infection of SLAM (CD150) Knockin Mice Reproduces Tropism and Immunosuppression in Human Infection
... the SLAM knockin mice allowed in vitro repli- cation of MV, but mature DCs did ...experiments, SLAM knockin mice did not allow MV replication unless they were crossed with mice lacking ...The V, C, ... See full document
10
Measles Virus Phosphoprotein Gene Products: Conformational Flexibility of the P/V Protein Amino-Terminal Domain and C Protein Infectivity Factor Function
... The measles virus (MV) P gene codes for three proteins: P, an essential polymerase cofactor, and V and C, which have multiple functions but are not strictly required for viral propagation in ... See full document
9
The N-glycan of the SCR 2 region is essential for membrane cofactor protein (CD46) to function as a measles virus receptor.
... for virus binding it is not important whether the N-glycans are present as complex or mannose-rich oligosaccharides ...be essential for preserving the recognition site on CD46 for MV ...The domain of ... See full document
5
Measles Virus-Induced Immunosuppression in SLAM Knock-In Mice
... Measles virus (MV) causes transient severe immunosuppression in patients, which may lead to secondary viral and bacterial infections, largely accounting for measles-related morbidity and ...the ... See full document
8
N glycosylation of the virus binding domain is not essential for function of the human poliovirus receptor.
... It seemed possible that differential glycosylation of hPVR Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest The human poliovirus receptor hPVR is a glycoprotein with thre[r] ... See full document
6
CD150 (SLAM) Is a Receptor for Measles Virus but Is Not Involved in Viral Contact-Mediated Proliferation Inhibition
... Since SLAM is a costimulatory molecule, the virus-SLAM interaction could possibly interfere with the stim- ulation of lymphocytes and contribute to immunosuppression during acute ...of virus ... See full document
7
Human cell receptor CD46 is down regulated through recognition of a membrane-proximal region of the cytoplasmic domain in persistent measles virus infection.
... by measles virus (MV) Biken strain (Biken-CV-1 cells) showed no cyto- pathic effects and lacked surface expression of a homolog of human cell receptor, membrane cofactor protein ...a ... See full document
8
Measles Virus V Protein Inhibits p53 Family Member p73
... Measles virus, a member of the Morbillivirus genus in the Paramyxoviridae family, is an enveloped negative-strand RNA virus that causes an acute illness, typically during ...childhood. Measles ... See full document
7
Essential Function of the Pseudorabies Virus UL36 Gene Product Is Independent of Its Interaction with the UL37 Protein
... an essential role during virion morphogenesis (30, ...Both virus mutants were able to enter RK13 cells, to produce nucleocapsids in the host-cell nucleus ...binding domain of UL36 in PrV-UL36BSF ... See full document
11
Physical association of moesin and CD46 as a receptor complex for measles virus.
... P receptor (7, 8) or the acetylcholine receptor ...with human CD46 expression vectors enhanced the infectivity with MV by about 100-fold for certain rodent cell lines, but not others, suggesting the ... See full document
9
CD46 Measles Virus Receptor Polymorphisms Influence Receptor Protein Expression and Primary Measles Vaccine Responses in Naive Australian Children
... with measles antibody ...cytokine receptor genes (6) that have been shown to influence measles vaccine responses in ...other measles-specific receptor, signaling lymphocyte activation ... See full document
7
Measles virus-induced changes in leukocyte function antigen 1 expression and leukocyte aggregation: possible role in measles virus pathogenesis.
... 1075-1079 0022-538X/93/021075-05$02.00/0 Copyright © 1993, American Society for Microbiology NOTES Measles Virus-Induced Changes in Leukocyte Function Antigen 1 Expression and Leukocyte [r] ... See full document
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Ontogeny of the v-erbA oncoprotein from the thyroid hormone receptor: an alteration in the DNA binding domain plays a role crucial for v-erbA function.
... 2037 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The avian erythroblastosis virus v-erbA oncogene is imprecisely derived from a cellular gene c-erbA encoding a thyr[r] ... See full document
10
Moesin Is Not a Receptor for Measles Virus Entry into Mouse Embryonic Stem Cells
... in measles virus (MV) entry was investigated with moesin-positive and -negative mouse embryonic stem (ES) ...express human CD46, a 100-fold increase in syncytium formation was observed with these ... See full document
7
Mice immunized with measles virus develop antibodies to a cell surface receptor for binding virus.
... In this report, we show that mice immunized with MV develop antibodies 30 to 35 days after immunization which react with cell surface receptors for binding MV by several criteria: these [r] ... See full document
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