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[PDF] Top 20 Dynamics and modulation of human immunodeficiency virus type 1 transcripts in vitro and in vivo.

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Dynamics and modulation of human immunodeficiency virus type 1 transcripts in vitro and in vivo.

Dynamics and modulation of human immunodeficiency virus type 1 transcripts in vitro and in vivo.

... cell-free virus and infected cells is much higher than previ- ously believed (47, 67, ...CD4 1 T cells (55). In this study, the pattern of viral transcripts was also assayed in PBMCs from infected ... See full document

11

RNA aptamers selected to bind human immunodeficiency virus type 1 Rev in vitro are Rev responsive in vivo.

RNA aptamers selected to bind human immunodeficiency virus type 1 Rev in vitro are Rev responsive in vivo.

... A variety of gene therapies have been proposed that involve using antisense or catalytic RNAs to disable the RRE (33, 46, 55, 56), RNA decoys to sequester Rev (29, 30), or transdomi- nant Rev proteins to inhibit Rev ... See full document

9

Target Cell Type-Dependent Modulation of Human Immunodeficiency Virus Type 1 Capsid Disassembly by Cyclophilin A

Target Cell Type-Dependent Modulation of Human Immunodeficiency Virus Type 1 Capsid Disassembly by Cyclophilin A

... wild-type virus capsids, and the effect of Cs on this process, in infected HeLa ...control virus lacking the VSV-G envelope glycoprotein ...reverse transcripts in infected HeLa cells. (A) ... See full document

12

In Vivo Evidence for Instability of Episomal Human Immunodeficiency Virus Type 1 cDNA

In Vivo Evidence for Instability of Episomal Human Immunodeficiency Virus Type 1 cDNA

... of human immunodeficiency virus type 1 (HIV-1) infection suppress plasma viremia to below detectable levels for prolonged ...in vitro experiments with conflicting results. ... See full document

8

Intravirion reverse transcripts in the peripheral blood plasma on human immunodeficiency virus type 1-infected individuals.

Intravirion reverse transcripts in the peripheral blood plasma on human immunodeficiency virus type 1-infected individuals.

... Genomic RNA was extracted from purified virions and treated with DNase to eliminate virion-associated HIV-1 DNA prior to reverse transcription into cDNA, in vitro, utilizing Moloney muri[r] ... See full document

7

In Vitro Intersubtype Recombinants of Human Immunodeficiency Virus Type 1: Comparison to Recent and Circulating In Vivo Recombinant Forms

In Vitro Intersubtype Recombinants of Human Immunodeficiency Virus Type 1: Comparison to Recent and Circulating In Vivo Recombinant Forms

... Identifying HIV-1 ISRs by HTA. The detection of env or gag DNA following PCR amplification with heterologous pairs of subtype-specific primers (i.e., b-e or e-b) is still not proof that intersubtype recombination ... See full document

14

Some Human Immunodeficiency Virus Type 1 Vpu Proteins Are Able To Antagonize Macaque BST-2 In Vitro and In Vivo: Vpu-Negative Simian-Human Immunodeficiency Viruses Are Attenuated In Vivo

Some Human Immunodeficiency Virus Type 1 Vpu Proteins Are Able To Antagonize Macaque BST-2 In Vitro and In Vivo: Vpu-Negative Simian-Human Immunodeficiency Viruses Are Attenuated In Vivo

... against human BST-2 (34). Cells were washed twice in ice-cold PBS containing 1% ...(anti-BST-2; 1:100) for 30 min at 4°C, washed twice with ice-cold PBS containing 1% BSA, followed by the ... See full document

8

Human Endothelial Cells Enhance Human Immunodeficiency Virus Type 1 Replication in CD4+ T Cells in a Nef-Dependent Manner In Vitro and In Vivo

Human Endothelial Cells Enhance Human Immunodeficiency Virus Type 1 Replication in CD4+ T Cells in a Nef-Dependent Manner In Vitro and In Vivo

... support virus production may be a result of their inability to adequately stimulate resting CD4 ⫹ T cells, but it may also indicate the requirement for active EC ...The human T cells were stained red with a ... See full document

13

Pharmacovirological Impact of an Integrase Inhibitor on Human Immunodeficiency Virus Type 1 cDNA Species In Vivo

Pharmacovirological Impact of an Integrase Inhibitor on Human Immunodeficiency Virus Type 1 cDNA Species In Vivo

... (Table 1). In the current INI in vivo study, levels of HIV-1 integrants and episomal two-LTR circles in the spleens of infected rats were inversely correlated (66-fold reduction versus 7-fold ... See full document

12

Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

... including modulation of glutathione, and NFκB- dependent and -independent pathways, were speculated to contribute to the observed inhibition of virus replica- tion, and it is possible that those mechanisms ... See full document

10

Human immunodeficiency virus type 1 envelope gene structure and diversity in vivo and after cocultivation in vitro.

Human immunodeficiency virus type 1 envelope gene structure and diversity in vivo and after cocultivation in vitro.

... 2 0022-538X/92/020875-11$02.00/0 Copyright C 1992, American Society for Microbiology Human Immunodeficiency Virus Type 1 Envelope Gene Structure and Diversity In Vivo and after Cocultiva[r] ... See full document

11

Modulation of Different Human Immunodeficiency Virus Type 1 Nef Functions during Progression to AIDS

Modulation of Different Human Immunodeficiency Virus Type 1 Nef Functions during Progression to AIDS

... in vitro activities of Nef change during the course of HIV-1 ...in vitro assay systems, (i) CD4 downregulation, (ii) enhancement of virion in- fectivity, and (iii) stimulation of HIV-1 ... See full document

9

Evolution of human immunodeficiency virus type 1 nef and long terminal repeat sequences over 4 years in vivo and in vitro.

Evolution of human immunodeficiency virus type 1 nef and long terminal repeat sequences over 4 years in vivo and in vitro.

... 225 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The evolution of an 851-bp segment of the human immunodeficiency virus type 1 HIV-1 genome encoding the nef open rea[r] ... See full document

7

Host-specific driving force in human immunodeficiency virus type 1 evolution in vivo.

Host-specific driving force in human immunodeficiency virus type 1 evolution in vivo.

... of human immunodeficiency virus type 1 (HIV-1) in vivo infection is the rapid generation and turnover of viral variants, resulting in a high degree of sequence diver- sity ... See full document

7

Cofactors for Human Immunodeficiency Virus Type 1 cDNA Integration In Vitro

Cofactors for Human Immunodeficiency Virus Type 1 cDNA Integration In Vitro

... around 1 NC molecule per 5 to 15 bp, potentially enough to coat the reactant ...in vivo (1a). HMGa1 apparently stimulates integra- tion in vitro by a different mechanism (11, ... See full document

6

In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor.

In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor.

... Transcriptional activation of homologous viral long terminal repeats by the human immunodeficiency virus type 1 or the human T-cell leukemia virus type 1 tat proteins occurs in the absen[r] ... See full document

10

Human Immunodeficiency Virus Type 1 Vpr Induces DNA Replication Stress In Vitro and In Vivo

Human Immunodeficiency Virus Type 1 Vpr Induces DNA Replication Stress In Vitro and In Vivo

... FIG. 2. Vpr fails to activate ATR in monocyte-derived macrophages. (A) Human MDM from healthy human donors were purified by adherence, cultured for 10 to 11 days, and then exposed to lentiviral vectors. ... See full document

12

Modulation of Sp1 Phosphorylation by Human Immunodeficiency Virus Type 1 Tat

Modulation of Sp1 Phosphorylation by Human Immunodeficiency Virus Type 1 Tat

... (Fig. 1 and ...In vitro kinase assays demonstrated that the physical presence of Tat augmented significantly phosphorylation of purified Sp1 in a manner mediated through the enzyme DNA-PK ... See full document

15

Conservation of an intact human immunodeficiency virus type 1 vif gene in vitro and in vivo.

Conservation of an intact human immunodeficiency virus type 1 vif gene in vitro and in vivo.

... vif-negative human immunodeficiency virus type 1 (HIV-1) is attenuated in certain cell lines and highly impaired in peripheral blood lymphocytes in ...replicating virus in ... See full document

8

Detection of Human Immunodeficiency Virus Type 1 Nucleocapsid Protein p7 In Vitro and In Vivo

Detection of Human Immunodeficiency Virus Type 1 Nucleocapsid Protein p7 In Vitro and In Vivo

... In summary, we developed an ECL-based p7 immunoassay with a dynamic range of 50 to 20,000 pg of p7 per ml. It was well suited to compete with p24 assays to monitor standard viral infections, independent of which ... See full document

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