[PDF] Top 20 The emerging role of insulin-like growth factors in testis development and function
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The emerging role of insulin-like growth factors in testis development and function
... Interestingly, insulin and IGF receptors also play a cru- cial role in mediating FSH ...SCs, testis weight and SC number were reduced by approximately 55-60% [65], compared with >70% for ... See full document
10
Insulin like growth factor binding proteins and mammary gland development
... mammary development and reduced invasion into the mammary fat ...apoptotic role of IGFBP-5. Despite the absence of any direct evidence for a role of IGFBPs other than IGFBP-5 in mammary gland ... See full document
9
Maternal H. pylori seropositivity is associated with gestational hypertension but is irrelevant to fetal growth and development in early childhood
... intrauterine growth restriction (IUGR) compared with HPSA-negative ...a role in driving IUGR [13, ...of insulin, insulin-like growth factors (IGFs), ... See full document
9
Insulin like growth factors and insulin like growth factor binding proteins in mammary gland function
... paracrine growth signal for neighbouring epithelial cells ...produced growth factors ...of development such as during alveolargenesis ... See full document
9
Investigation of insulin like growth factors/insulin like growth factor binding proteins regulation in metabolic syndrome patients
... of insulin and glucose metabolism [4, ...crucial role in the pathogenesis of obesity, insulin resistance, and development of MSx [4, ... See full document
5
Emerging role of insulin-like growth factor-binding protein 7 in hepatocellular carcinoma
... including growth-control genes, such as Src tyrosine kinases, Ras, Raf, MAPK, ERK, c-Jun N-terminal kinase, and a number of other genes probably through the inherent capability of HBV to integrate into the genome, ... See full document
11
Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model
... and growth factors. To determine the role of the insulin- like growth factors (IGFs) in this process we developed a transgenic model using the whey acidic protein (WAP) ... See full document
9
The emerging role of insulin like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs)
... in insulin-like growth factor 1 receptor (IGF1R) in medical ...key role in the growth and development of nor- mal ...tumor growth and metastases [3,4]. The biologic ... See full document
6
Intrauterine Growth Restriction: A Perspective for Pakistan
... low insulin levels will slow the growth rate in insulin-sensitive tissues such as skeletal muscle and liver, whereas brain growth is relatively ...the insulin like growth ... See full document
6
Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels.
... All SNPs were examined for deviation from Hardy-Weinberg equilibrium using the hwsnp function in the statistical pack- age Stata. Linear and logistic regression were used as appro- priate to investigate the effect ... See full document
14
Building Muscle: The Role of Insulin-Like Growth Factor Binding Protein-6 and Insulin-Like Growth Factors in the Differentiation of Placental Mesenchymal Stem Cells into Skeletal Muscle
... isolation. Like many developing progenitor cell types, the function of MSCs is affected by the surrounding microenvironment, and mimicking natural microenvironmental cues that support multipotent or ... See full document
248
Growth factors and apoptosis in development The role of insulin like growth factor I and TGFbeta1 in regulating cell growth and cell death in a human teratocarcinoma derived cell line
... Int I Oev BioI 39 759 764 (1995) 759 Growth factors and apoptosis in development The role of insulin like growth factor I and TGFB1 in regulating cell growth and cell death in a human teratocarcinoma[.] ... See full document
6
Expression of the insulin-like growth factor (IGF) system and steroidogenic enzymes in canine testis tumors
... that growth factors of the insulin-like growth factor regulatory system, such as insulin-like growth factor-I (IGF-I) and IGF-II, are involved in the pathobiology ... See full document
8
Assessing the role of insulin like growth factors and binding proteins in prostate cancer using Mendelian randomization:genetic variants as instruments for circulating levels
... 16 All SNPs were examined for deviation from Hardy-Weinberg equilibrium using the hwsnp function in the statistical package Stata. Linear and logistic regression were used as appropriate to investigate the effect ... See full document
44
Effects of Hibiscus sabdariffa Linn. on Malondialdehyde and Glutathione Peroxidase in an Overtraining Rat Model characterized by Growth Hormone, Insulin-like Growth Factor-1, and Insulin-like Growth Factor Binding Protein-3
... rat growth hormone (GH ELISA Kit - Cusabio®), for rat insulin-like growth factor 1 (IGF-1 ELISA Kit - Cusabio®), and for rat insulin-like growth factor binding protein 3 ... See full document
9
Muscle growth and flesh quality of farmed Atlantic halibut (Hippoglossus hippoglossus) in relation to season of harvest
... of growth (Rowlerson et ...1998). Growth of the fast muscle involves the hypertrophy of the embryonic fibres until around 150 degree days (10 mm LS) after which additional myotubes are formed (Galloway et ... See full document
280
The matrix metalloproteinase and insulin-like growth factor system in oral cancer – a prospective clinical study
... There are numerous studies indicating an important role of MMP-2, MMP-3, MMP-13, IGF-1, and IGFBP-3 in dif- ferent malignancies. However, to the best of our knowledge, there is no report available on serum status ... See full document
7
Overexpression of IGF2 and IGF2 receptor in malignant solitary fibrous tumor with hypoglycemia: a case report
... The tumor measured 34 cm at the major axis and weighed 1350 g and was well demarcated by a fibrous membrane. The resected surface was elastic, firm, had an ivory-like appearance, and was multilobulated with ... See full document
5
Targeting insulin-like growth factor axis in hepatocellular carcinoma
... of growth hormone could also contribute to the disappointing activity of this class of ...effector function, therefore can potentially minimize toxicities in healthy tissues expressing IGF-1R ...to ... See full document
11
449.pdf
... The results indicate that dpl00 could be affinity labeled with all the insulin-like and EGF-like growth factors tested (TGF- alpha, EGF, insulin, and IGF-I), and that radiolabel[r] ... See full document
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