[PDF] Top 20 Exercise for the heart: signaling pathways
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Exercise for the heart: signaling pathways
... physical exercise and CVD has increasingly been in the spotlight in recent ...in exercise enjoy more desirable health outcomes, including better health-related quality of life and functional capacity ... See full document
12
Exercise training in heart failure
... an exercise program was historically consid- ered to be ill-advised for patients with significant left ventric- ular ...physical exercise was the standard recommendation for all patients suffering from ... See full document
6
Effect of physical exercise training in patients with Chagas heart disease: study protocol for a randomized controlled trial (PEACH study)
... York Heart Association class I or II in the previous 3 months, with clinical stability by investigator judg- ment, (4) clinical treatment according to HF guidelines, including treatment with angiotensin-converting ... See full document
11
The effects of isometric handgrip exercise on post-exercise hypotension, ambulatory arterial blood pressure and heart rate variability in individuals medicated for hypertension
... post-aerobic exercise PEH, one of which is a reduction in cardiac ...aerobic exercise, individuals with HT have sustained reductions in cardiac output (26), likely due to a reduction in blood volume, ... See full document
140
Effect of exercise therapy on established and emerging circulating biomarkers in patients with heart failure: a systematic review and meta-analysis
... Background Biomarkers are important in the diagnosis, risk stratification and management of patients with heart failure (HF). The established biomarkers of myocardial stretch, brain natriuretic peptide (BNP) and ... See full document
16
Estrogen regulation of protein expression and signaling pathways in the heart
... In addition to altering mRNA levels, estrogen can acti- vate signaling pathways [7,36] that alter protein PTMs [37,38], which can lead to additional estrogen-dependent changes in cardiac function. Lagranha ... See full document
7
Free fatty acid can induce cardiac dysfunction and alter insulin signaling pathways in the heart
... insulin signaling in insulin receptor substrate 1 (IRS-1) -PI3K activity ...insulin signaling in cardiomyocytes and the pathophysiology of heart failure in insulin-resistant states are incompletely ... See full document
8
Sex-specific variation in signaling pathways and gene expression patterns in human leukocytes in response to endotoxin and exercise
... inflammation-related pathways TLRs, cytosolic DNA sensing, and RIG-I like ...through exercise while women had a higher baseline. Finally, exercise also modified a set of genes related to brain ... See full document
11
In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration
... identified pathways are essential for cardiomyocyte proliferation during heart regeneration, we tested the effects of ...Tgfβ signaling pathways are necessary for normal heart ... See full document
7
Retinoic acid signaling pathways
... Retinoic acid (RA) is derived from retinol (vitamin A) as a metabolic product. RA exists in several isomeric forms including all-trans-RA, 9-cis-RA and 13-cis-RA; however, all-trans-RA is the primary ligand during ... See full document
7
Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial Igf2
... WNT signaling pathways during myocardial expansion has not been reported (Merki et ...in heart organ cultures; however, as Fgf9 is expressed primarily in the endocardium and not expressed in the ... See full document
10
CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo
... Synergy between CaMKIV and calcineurin/NFAT3 path- ways in vivo. Previously, we showed that expression of a constitutively active mutant form of NFAT3, called NFAT∆317, in the heart resulted in hypertrophy (12). ... See full document
13
Impact of steroid hormone signals on Drosophila cell cycle during development
... the signaling pathways affecting these cell cycles are well characterised ...key signaling mole- cule in the morphogenesis of the wing is the Wingless (Wg) protein, a member of the Wnt family of ... See full document
13
Gastric Cancer MicroRNAs Meta-signature
... In order to minimize these limitations, we aimed at performing a meta-analysis applying the robust rank aggregation method, followed by pathway enrichment to identify deregulated miRNAs and pathways in GC. This ... See full document
9
Linearity in Cell Signaling Pathways
... understanding signaling pathway function Signaling pathways have been well-characterized over the last few decades, and the molecular interactions that govern each pathway are largely ...a ... See full document
102
Original Article Upregulation of autophagy genes and the unfolded protein response in human heart failure
... and heart failure [10, 14], elevations in all three UPR pathways have been ...failing heart tissue, elevated PERK and down- stream CHOP mRNA has been reported from 3 human heart failure ... See full document
8
In silico identification of potential key regulatory factors in smoking-induced lung cancer
... Lung cancer is a complex and highly heterogeneous di- sease involving multiple signaling pathways [1]. It is the leading cause of cancer mortality in men and the second leading cause in women worldwide [2]. ... See full document
11
An integrated analysis of key microRNAs, regulatory pathways and clinical relevance in bladder cancer
... functional enrichment analysis indicated that the significant DEGs in BC were related to classical cancer pathways such as cell cycle and MAPK signaling pathways. The key DEGs such as CDK1, CCNB1, ... See full document
11
Functional phosphoproteomic mass spectrometry-based approaches
... cellular signaling pathways, a protein A phosphory- lates protein B, and B phosphorylates ...another signaling pathway, protein D phosphorylates A, or phosphorylates protein ... See full document
10
A network pharmacology-based strategy deciphers the underlying molecular mechanisms of Qixuehe Capsule in the treatment of menstrual disorders
... two pathways were significantly decreased at the cerebellar postsynaptic density of mouse cerebellum exposed to arsenic, which is a neurotoxin that induces dysfunction of learning and memory ... See full document
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