[PDF] Top 20 Fibrinogen deficiency is compatible with the development of atherosclerosis in mice
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Fibrinogen deficiency is compatible with the development of atherosclerosis in mice
... 2/2 mice, a number of secondary challenges in these animals could conceivably render the rate of atherogenesis highly-dependent on ...of atherosclerosis that is mechanistically tied to fi- ...E–deficient ... See full document
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Low levels of tissue factor are compatible with development and hemostasis in mice
... sepsis, atherosclerosis, and can- cer, is associated with life-threatening thrombosis ...In atherosclerosis, plaque rupture and exposure of blood to TF expressed by macrophage-derived foam cells may be ... See full document
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Original Article Inhibition of NOX4 prevents the development of atherosclerosis in Ldlr mice
... phages [6]. Endothelium-dependent diastolic function is significantly enhanced in patients with inherited NOX2 deficiency [6]. NOX5 pro- motes endothelium-dependent diastole in human coronary artery disease caused ... See full document
8
Deficiency of Glycine N-Methyltransferase Aggravates Atherosclerosis in Apolipoprotein E-Null Mice
... The mechanism underlying the dysregulation of cholesterol metabolism and inflammation in atherogenesis is not understood fully. Glycine N-methyltransferase (GNMT) has been implicated in hepatic lipid metabolism and the ... See full document
9
PPARα deficiency reduces insulin resistance and atherosclerosis in apoE null mice
... wall. Mice deficient in LPL (12) or CD36 (13) are resistant to ...the development of foam cells, essential partic- ipants in the atherosclerotic ...established atherosclerosis (15), and PPARγ ligands ... See full document
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Phospholipase C β3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice
... the development of athero- sclerotic ...from mice lacking PLC β2, PLC β3, or both PLC isoforms and found that PLC β3 is the major functional PLC β isoform in murine ...β3 deficiency did not affect ... See full document
11
Interleukin-10 Deficiency Increases Atherosclerosis, Thrombosis, and Low-density Lipoproteins in Apolipoprotein E Knockout Mice
... lesion development only in male mice ...on atherosclerosis relates to differences in the sexes’ reactivity to ...knockout mice, the accompanying Th1 IgG switch was detectable earlier in female ... See full document
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Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice
... the development of novel therapies directed at HDL, such as CETP inhibitors, niacin with flushing inhibitors, infusion of apoA-1 or apoA-1–like pep- tides, and LXR activators (52, ...CETP deficiency or in ... See full document
10
MCP 1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B
... E–deficient mice (9–11) and low-densi- ty lipoprotein (LDL) receptor–deficient mice ...these mice causes marked retardation of the clearance of lipopro- teins from the plasma, leading to ...the ... See full document
7
C5L2 Deficiency Enhances Development of Atherosclerosis in ApoE Knockout Mice
... the development of ...develop atherosclerosis naturally, we used an atherosclerosis-prone model, the ApoEKO mouse, and crossed it with C5L2KO mice to further evaluate how the disruption of ... See full document
14
The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E / mice
... the development of athero- sclerosis (15, 16, ...carotid atherosclerosis as mea- sured by ultrasound in humans (16) and with the extent of aor- tic atherosclerosis in LDL-receptor 2/2 mice ... See full document
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A SNP in <em>CYP2C8</em> is not associated with the development of bisphosphonate-related osteonecrosis of the jaw in men with castrate-resistant prostate cancer
... the development of osteone- crosis of the jaw (ONJ) in patients receiving bisphosphonates (BPs) for multiple ...the development of ONJ in men receiving BPs for bone metastases from prostate cancer, we ... See full document
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The intermediate conductance calcium activated potassium channel KCa3 1 contributes to atherogenesis in mice and humans
... sentative images of atherosclerotic lesions in aortic trees from the ascending aorta to the iliac bifurcation (left) and in carotid arteries from the common carotid artery to the cervical bifurcation (right; stained ... See full document
14
Impress of Betatrophin in the Treatment of Mice With Diabetes Type 1
... in mice with type1 diabetes. This experimental study was based on 30 mice, the study was carried out at animal house, college of medicine-University of ...These mice divided into three group’s first ... See full document
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Degarelix treatment is compatible with diabetes and antithrombotic therapy in patients with prostate cancer
... In this study, we analyzed the potential for a causal association between degarelix therapy discontinuation and the most common preexisting condition (diabetes) or co- treatment (antithrombotic therapy) in a cohort of ... See full document
8
The Significance of Spermidine and Spermine in Association with Atherosclerosis in Sera of Iraqi Patients
... in atherosclerosis focused on a composition of atherosclerotic plaque differences in men and women with acute coronary syndromes (ACS) 32,33 , which, as this study suggests, ... See full document
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c Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow
... Local flow patterns determine the uneven distribution of atherosclerotic lesions. This research aims to elucidate the mechanism of regulation of nuclear translocation of Yes- associated protein (YAP) under oscillatory ... See full document
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Roles of thromboxane A2 and prostacyclin in the development of atherosclerosis in apoE deficient mice
... Quantification of atherosclerosis. Atherosclerotic lesions were quantified by en face analysis of the whole aorta and by cross-sectional analysis of the proximal aorta and the innominate artery. For en face ... See full document
12
Possibilities of logorhythmics in the development of preschoolers with mental retardation
... the beginning of the study children could hardly concentrate on completing the assignment for a long time. Many of them also suffered from the level of development of fine motor skills which is very important for ... See full document
8
Treatment of congenital fibrinogen deficiency: overview and recent findings
... 51. MacKinnon HH, Fekete JF. Congenital afibrinogenemia. Vascular changes and multiple thromboses induced by fibrinogen infusions and contraceptive medication. Can Med Assoc J. 1971;104(7):597–599. 52. ... See full document
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