[PDF] Top 20 Functional interactions between papillomavirus E1 and E2 proteins.
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Functional interactions between papillomavirus E1 and E2 proteins.
... of E2 specifically required for its activity in replication is the N-terminal activation ...with E1 in vitro (59), is also necessary and sufficient for replication in vivo when tethered to DNA through an ... See full document
11
CK2 Phosphorylation Inactivates DNA Binding by the Papillomavirus E1 and E2 Proteins
... pressed E2 protein and 20 l of protein G agarose beads for 1 h at ...an E2 binding site (E2 BS), and a larger, nonspecific probe lacking an E2 ... See full document
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Cottontail Rabbit Papillomavirus E1 and E2 Proteins Mutually Influence Their Subcellular Localizations
... The papillomavirus (PV) E2 protein is a nuclear, sequence-specific DNA- binding protein that regulates transcription and nuclear retention of viral ...genomes. E2 also interacts with the viral ... See full document
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A Fifteen-Amino-Acid Peptide Inhibits Human Papillomavirus E1-E2 Interaction and Human Papillomavirus DNA Replication In Vitro
... the E2 binding site of E1. The E1-E2 interaction and peptide inhibition experiments presented here indicate functional conservation in E1-E2 rec- ognition and interaction ... See full document
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Amino-terminal domains of the bovine papillomavirus type 1 E1 and E2 proteins participate in complex formation.
... The papillomavirus E1 and E2 open reading frames encode proteins important in the regulation of viral transcription and DNA ...bovine papillomavirus type 1 (BPV-1) E1 gene ... See full document
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Functional Interaction of the Bovine Papillomavirus E2 Transactivation Domain with TFIIB
... and functional interactions be- tween the E2 N-terminal TAD and ...the E2 TAD retained purified FLAG-TFIIB, both produced in ...nal E2 association with TFIIB occurs through direct ... See full document
7
Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells
... heterologous proteins on a large scale in eukaryotic cells [20] and the proven technology has resulted in several commercially available veterinary vaccines [21], including a veterinary subunit vaccine targeting ... See full document
13
Functional Mapping of the DNA Binding Domain of Bovine Papillomavirus E1 Protein
... for E2 interaction support partial in vivo DNA ...by E2 suggested that they may retain sufficient function to support DNA ...full-length E1 in mammalian cells for in vivo DNA replication ...wild-type ... See full document
13
Functional Mapping of the Human Papillomavirus Type 16 E1 Cistron
... engineered E2 or E1 expressor constructs ...influenced E1-dependent plasmid ...the E2-expressing plasmid A2 (i.e., the E1 ⫺ ,E8 ⫺ ,E7 ⫺ construct) resulted in a ⬍ 2-fold increase in ... See full document
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Conserved interaction of the papillomavirus E2 transcriptional activator proteins with human and yeast TFIIB proteins.
... BPV-1 E2 capable of bind- ing hTFIIB did not all overlap ...lie between aa 161 and ...BPV-1 E2 that is essential for transactivation ...to E2-TR, an E2 species present in ... See full document
7
Brd4-Independent Transcriptional Repression Function of the Papillomavirus E2 Proteins
... of E2 and may there- fore be recruited to E2-responsive promoters in an E2 tran- scription factor-dependent manner ...of E2 is conserved among different PV groups and suggests an essential ... See full document
11
Functional Interaction between the Bovine Papillomavirus Virus Type 1 Replicative Helicase E1 and Cyclin E-Cdk2
... that E1 alone can efficiently drive multiple rounds of DNA synthesis from a sin- gle BPV plasmid, as do the initiators of lytic viruses such as SV40 large T antigen ...that E1-mediated DNA replication may ... See full document
8
Werner Helicase Control of Human Papillomavirus 16 E1 E2 DNA Replication Is Regulated by SIRT1 Deacetylation
... viral proteins, E1 and E2, activate viral replication in association with cellular factors and stimulate the DNA damage response (DDR) during the replication ...process. E1-E2 uses ... See full document
21
AMF-1/Gps2 Binds p300 and Enhances Its Interaction with Papillomavirus E2 Proteins
... AMF-1, E2, and E1 by p300. In vitro acetylation of p53, AMF-1, E2, and E1 was tested using Sf9 cell extracts con- taining each of these proteins and extract containing ...AMF-1, ... See full document
8
E1 Protein of Bovine Papillomavirus Type 1 Interferes with E2 Protein-Mediated Tethering of the Viral DNA to Mitotic Chromosomes
... with E1 to the viral origin (15, 20, 21, 29). A very stable hetero- typic E2 dimer and E1 monomer complex can form without DNA, yet the physiological significance of this complex is un- ...actions ... See full document
12
Evidence Supporting a Role for TopBP1 and Brd4 in the Initiation but Not Continuation of Human Papillomavirus 16 E1/E2-Mediated DNA Replication
... differences between the HPV types in their requirement for Brd4 in genome replication and ...E2 proteins. The results also confirm the role for TopBP1 in mediating E1-E2 DNA replication ... See full document
12
Interactions between geminivirus replication proteins.
... The mechanism by which AL3 enhances viral DNA accumu- lation may involve its ability to interact with AL1. The AL3 protein sequence shows no homology to any known enzymatic motifs. Therefore, it is more likely that the ... See full document
6
Role of the ATP-Binding Domain of the Human Papillomavirus Type 11 E1 Helicase in E2-Dependent Binding to the Origin
... of E1 by E2 to the HPV origin is an essential step in the initiation of viral DNA ...of E1 (amino acids 353 to 649) is sufficient for interaction with the TAD of E2 (amino acids 1 to 209) and ... See full document
12
The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro.
... In order to screen recombinant viral isolates for El expression, Sf9 cells were infected with each of the isolates or wild-type virus, and at 60 h postinfection, proteins were metabolica[r] ... See full document
8
Mapping and characterization of the interaction domains of human papillomavirus type 16 E1 and E2 proteins.
... using E1 amino-terminal constructs as bait in the LexA-based system, we used a second version of yeast two-hybrid system (Gal4- based system) to examine HPV16 E1-E2 ...DBD-HPV16 E2 fusion ... See full document
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