[PDF] Top 20 Gene conversion in the evolution of both the H-2 and Qa class I genes of the murine major histocompatibility complex.
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Gene conversion in the evolution of both the H-2 and Qa class I genes of the murine major histocompatibility complex.
... For each putative conversion event we have analyzed the sequences and gene regions in- volved, the apparent length of the event, and its effect on protein sequence [r] ... See full document
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Cellular and Molecular Requirements for Association of the Murine Cytomegalovirus Protein m4/gp34 with Major Histocompatibility Complex Class I Molecules
... The major histocompatibility complex (MHC) class I path- way of antigen presentation is the means by which the internal contents of a cell are displayed to the immune system, and in ... See full document
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Rapid Evolution of Major Histocompatibility Complex Class I Genes in Primates Generates New Disease Alleles in Humans via Hitchhiking Diversity
... MHC class I region: One bacterial artificial chromosome (BAC) library, CHORI-250, constructed from white blood cells of the male rhesus macaque was obtained from the BACPAC Resource Center at the Children’s ... See full document
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Transcriptional and posttranscriptional regulation of class I major histocompatibility complex genes following transformation with human adenoviruses.
... Tumorigenicity of hamster and mouse cells transformed by adenovirus type 2 and 5 is not influenced by the level of class I major histocompatibility antigens expressed on the cells.. The [r] ... See full document
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Targeted infection of human cells via major histocompatibility complex class I molecules by Moloney murine leukemia virus-derived viruses displaying single-chain antibody fragment-envelope fusion proteins.
... for gene transfer are derived from the Moloney murine leuke- mia virus (MoMuLV) and are usually of either the ecotropic (which infects murine cells only) or the amphotropic (which infects both ... See full document
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PROTEIN MODELLING OF THE GENES OF ARTHRITIS: A REVIEW
... for genes which cause Rheumatoid and gout ...research. Genes responsible for this were found out through literature survey and referring to previously done research on this ...54 genes found to play ... See full document
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Cloned long-term cytolytic T-lymphocyte line with specificity for an immediate-early membrane antigen of murine cytomegalovirus.
... 57, 1986 class I glycoproteins encoded by genes of the K or DL loci of the murine major histocompatibility complex MHC 13, 27, simian virus 40-transformed cell lines 14 derived from the [r] ... See full document
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Murine Cytomegalovirus Perturbs Endosomal Trafficking of Major Histocompatibility Complex Class I Molecules in the Early Phase of Infection
... or conversion into recycling endo- somes or LEs ...endosomal conversion dis- playing various stages of converting endosomes, a process which is rapid in untreated cells (46) and very slow in MCMV-infected ... See full document
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The r144 Major Histocompatibility Complex Class I-Like Gene of Rat Cytomegalovirus Is Dispensable for both Acute and Long-Term Infection in the Immunocompromised Host
... r144 gene encodes an MHC class I ...r144 gene, which putatively encodes an MHC class I ...MHC class I-like and mammalian MHC class I proteins, a ... See full document
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Deficient Major Histocompatibility Complex-Linked Innate Murine Cytomegalovirus Immunity in MA/My.L-H2b Mice and Viral Downregulation of H-2k Class I Proteins
... MHC class I proteins for lysoso- mal degradation (28), gp40 blocks endoplasmic reticulum- Golgi MHC class I export (42), and gp34 escorts class I molecules to the cell surface to ... See full document
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The Major Histocompatibility Complex Class I Genes of Zebrafish.
... the genes of the major histocompatibility complex (MHC) were named after the discovery that they encode the primary antigens responsible for determining transplant compatibility (Klein 2001), ... See full document
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Human Cytomegalovirus Disrupts the Major Histocompatibility Complex Class I Peptide-Loading Complex and Inhibits Tapasin Gene Transcription
... tapasin gene expression at a pretranscrip- tional ...tapasin gene expression on a pretran- scriptional level, the stability of tapasin RNA was ...24 h, starting at 36 h ...target genes ... See full document
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Evolutionary Relationships of Major Histocompatibility Complex Class I Genes in Simian Primates
... cates gene duplication and the root of the group B or G tree is assumed to be the same as that placed when all sequences are ...Table 2, the MHC symbol is followed by a four- letter abbreviation system ... See full document
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Down-regulation of major histocompatibility complex class I synthesis by murine cytomegalovirus early gene expression.
... The results indicate that MCMV infection down-regulates synthesis of both H-2Kb and H-2Db and slows considerably the rates of accumulation and maturation of these molecules within the in[r] ... See full document
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Progress in spondylarthritis Progress in studies of the genetics of ankylosing spondylitis
... hla.alleles.org/class1.html) now reports 46 B27 subtypes, making B27 one of the more polymorphic of HLA-B alleles. The significance of the B27-subtype studies is that they provide important information helpful in ... See full document
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Prognostic value of soluble major histocompatibility complex class I polypeptide-related sequence A in non-small-cell lung cancer – significance and development
... Soluble major histocompatibility complex class I polypeptide-related sequence A (sMICA) is a useful marker in surveillance of lung ... See full document
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Polymorphism in regulatory gene sequences
... To what extent are polymorphisms in the regulatory regions subject to natural selection? They could in principle be neutral, transient (reflecting allele replacement or popula- tion mixing) or balanced (through increased ... See full document
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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey
... subunit may induce the degradation of α subunit or cause an inhibitory feedback response on the transcription of α subunit. Nevertheless, the remaining α subunits may be sufficient for NK inhibition. In addition, ... See full document
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HLA C and HIV 1: friends or foes?
... specific MHC class I alleles and HIV-1 control strongly supports this idea. Early studies performed in the late 1980′s on small cohorts of AIDS patients reported an increased frequency of C*04 and B*35 in ... See full document
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Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions
... The histopathological features of the cortical tuber samples included cortical dyslamination, giant cells, dys- plastic neurons and astrogliosis [21,22]. TSC1 mutations were detected in one patient and TSC2 mutations in ... See full document
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