[PDF] Top 20 Herpes Simplex Virus type 1 lytic viral gene expression during the establishment and maintenance of latency
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Herpes Simplex Virus type 1 lytic viral gene expression during the establishment and maintenance of latency
... the establishment of latency per se but viral replication in the skin increases the number of virus genomes that can gain access to neurons, and influences the size of the latent HSV-1 ... See full document
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Herpes Simplex Virus Type 1 Promoter Activity during Latency Establishment, Maintenance, and Reactivation in Primary Dorsal Root Neurons In Vitro
... study herpes simplex virus (HSV) latency establishment, maintenance, and ...of viral gene expression in neurons following infection with ... See full document
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The Latency-Associated Transcript Gene Enhances Establishment of Herpes Simplex Virus Type 1 Latency in Rabbits
... The latency-associated transcript (LAT) gene the only herpes simplex virus type 1 (HSV-1) gene abundantly transcribed during neuronal latency, ... See full document
7
Held, Kathrin (2012): Control of herpes simplex virus type 1 latency in human trigeminal ganglia. Dissertation, LMU München: Fakultät für Biologie
... in lytic infection with lysis of the epithelial or mucosal cells, and subsequent release of infectious ...The virus then travels via retrograde transport to the cell body of the neurons, which are located ... See full document
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Evidence that two latency-associated transcripts of herpes simplex virus type 1 are nonlinear.
... the establishment or the maintenance of ...that expression of numerous copies of a circular viroid RNA was associated with specific methylation of corresponding inte- grated DNA sequences ... See full document
6
BFRF1 of Epstein-Barr Virus Is Essential for Efficient Primary Viral Envelopment and Egress
... Epstein-Barr virus (EBV) is one of the eight known human ...the expression of a limited set of viral genes (25). Viral reactivation from the latent state either oc- curs spontaneously or is ... See full document
10
An Immortalized Human Dorsal Root Ganglion Cell Line Provides a Novel Context To Study Herpes Simplex Virus 1 Latency and Reactivation
... induced expression of  -III tubulin and of peripherin supported the identification of a sensory neuron-associated ...selected during early optimization studies based on overall cell viability counts (data ... See full document
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Genetic Studies Exposing the Splicing Events Involved in Herpes Simplex Virus Type 1 Latency-Associated Transcript Production during Lytic and Latent Infection
... of lytic 2-kb ...from lytic or latent KOS infections, showed the joining of upstream and downstream sequences precisely at the predicted exon boundaries ...in lytic and latent infection, which ... See full document
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The latency-associated promoter of herpes simplex virus type 1 requires a region downstream of the transcription start site for long-term expression during latency.
... The latency-associated transcript (LAT) promoter of herpes simplex virus type 1 (HSV-1) is unique among the many promoters on the viral genome in that it remains ... See full document
6
Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation in Mice
... nonessential viral genes, including the ...establish latency in the PNS and to be ...and/or establishment of latency is dependent on the in vivo model, animal species, route of infection ... See full document
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A novel latency-active promoter is contained within the herpes simplex virus type 1 UL flanking repeats.
... The nucleotide sequence, 5' end, promoter domain, and kinetics of expression of the gene encoding the herpes simplex virus type 2 latency-associated transcript.. Promoter of the latency-[r] ... See full document
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Accumulation of Viral Transcripts and DNA during Establishment of Latency by Herpes Simplex Virus
... tk gene which includes the 59 one-third of the gH gene ...gC gene (pEcoRI-BamHI-I-I) (12) into the EcoRI and BamHI sites of Bluescript II KS1 (Stratagene), placing it under the control of the ... See full document
9
The Histone Variant H3.3 Regulates Gene Expression during Lytic Infection with Herpes Simplex Virus Type 1
... What mechanism could be responsible for the selective de- position of H3.3 at early infection times? It has previously been hypothesized that RNA polymerase may displace nucleo- somes, leading to naked DNA at actively ... See full document
6
Two herpes simplex virus type 1 latency-active promoters differ in their contributions to latency-associated transcript expression during lytic and latent infections.
... nt 1 66 to 1 27 relative to the previously mapped 5 9 end of the 2-kb LAT ...infecting virus contained both, either, or neither of the LAP ... See full document
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Gene expression during reactivation of herpes simplex virus type 1 from latency in the peripheral nervous system is different from that during lytic infection of tissue cultures.
... Herpes simplex virus (HSV) replicates in peripheral tissues and forms latent infections in neurons of the peripheral nervous ...from latency by various stimuli to cause recurrent disease. ... See full document
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Herpes Simplex Virus Type 1 Latency-Associated Transcripts Suppress Viral Replication and Reduce Immediate-Early Gene mRNA Levels in a Neuronal Cell Line
... for viral replication suppression by the LATs, we chose first to examine the influence of LATs on ICP0 gene ...of 1 (Fig. 3A), an HSV-1 MOI that also showed effective suppression of ... See full document
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Herpes Simplex Virus Virion Host Shutoff (vhs) Activity Alters Periocular Disease in Mice
... During lytic infection, the virion host shutoff (vhs) protein of herpes simplex virus (HSV) mediates the rapid degradation of RNA and shutoff of host protein ...HSV type 1 ... See full document
7
Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency.
... between 1 and 25 ng per reaction mixture. Amplification and analysis of HSV-1 and rabbit a -actin ...a-actin gene and a 243-bp sequence of the HSV-1 RR gene were coamplified from the ... See full document
5
The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency.
... wild type in vivo in this site ...snout, establishment is less efficient in TG neurons and reactivation is delayed in coculti- vation cultures in ...LAT expression (6; also, this ...the type ... See full document
9
Expression of Herpes Simplex Virus ICP0 Inhibits the Induction of Interferon-Stimulated Genes by Viral Infection
... acting viral mechanisms are difficult to ...HSV gene products may be sufficient for this activity (45, ...such gene product is ...stimulate viral gene expression and contribute ... See full document
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