[PDF] Top 20 Herpes Simplex Virus Type 1 UL34 Gene Product Is Required for Viral Envelopment
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Herpes Simplex Virus Type 1 UL34 Gene Product Is Required for Viral Envelopment
... growth, viral egress, and cell-cell ...infectious virus production, monolayer cultures of noncomple- menting 143B and 143/1099E cells were infected with vRR1072 at a multiplicity of infection of 10, washed ... See full document
13
Herpes Simplex Virus 1-Encoded Protein Kinase UL13 Phosphorylates Viral Us3 Protein Kinase and Regulates Nuclear Localization of Viral Envelopment Factors UL34 and UL31
... HSV-1 envelopment factors UL34 and UL31, showing that these viral proteins are localized abnormally in punctate struc- tures at the nuclear membrane in cells infected with recombi- nant ... See full document
11
The Herpes Simplex Virus Type 1 UL17 Gene Encodes Virion Tegument Proteins That Are Required for Cleavage and Packaging of Viral DNA
... During herpes simplex virus type 1 (HSV-1) infection, indi- vidual viral genomes are cleaved from intranuclear con- catameric viral DNA and packaged into ... See full document
10
Herpes Simplex Virus Type 1 Cytoplasmic Envelopment Requires Functional Vps4
... of viral cores across cellular membranes, in an extra- cellular direction, to allow the newly formed virions to be released from an infected ...of viral envelopes: the use of the cellular multivesicular ... See full document
8
Emerin Is Hyperphosphorylated and Redistributed in Herpes Simplex Virus Type 1-Infected Cells in a Manner Dependent on both UL34 and US3
... not required for infection-dependent changes in nuclear shape and emerin ...(lanes 1 to 3 and 10 to ...lanes 1 to 8 and lanes 9 to 15 are from separate ...or UL34-null-infected Vero cells ... See full document
12
Ultrastructural Localization of the Herpes Simplex Virus Type 1 UL31, UL34, and US3 Proteins Suggests Specific Roles in Primary Envelopment and Egress of Nucleocapsids
... pseudorabies virus (PrV), and betaherpesviruses such as human ...bearing viral glycoproteins previously modified by transit through the nor- mal secretory ... See full document
14
UL20 Protein Functions Precede and Are Required for the UL11 Functions of Herpes Simplex Virus Type 1 Cytoplasmic Virion Envelopment
... virion envelopment is thought to be me- diated by complex interactions among tegument proteins and viral glycoproteins embedded in the TGN ...of viral glycoproteins have been shown to either interact ... See full document
12
Nucleolin Is Required for Efficient Nuclear Egress of Herpes Simplex Virus Type 1 Nucleocapsids
... and viral proteins; and affects various aspects of cellular functions, in- cluding transcription mediated by RNA polymerase II, rRNA gene transcription, rRNA folding, pre-rRNA maturation, as- sembly of ... See full document
12
Viral replication is required for induction of ocular immunopathology by herpes simplex virus.
... HSV type 1 (HSV-1) RE and HSV-1 ...d301 virus (14) contains a deletion in the ICP8 gene. This b gene product is a major viral DNA-binding protein and is ... See full document
7
Nucleolin Is Required for an Efficient Herpes Simplex Virus Type 1 Infection
... regulation, viral replication, and cellular stress re- sponses (3, ...like viral DNA replication, virus assembly, and control of intracellular trafficking (for reviews see references 22 and ...of ... See full document
12
Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates.
... nuclease gene of herpes simplex virus type 1 (HSV-1) (nuc mutations) induce almost wild-type levels of viral DNA; however, mutant viral yields are ... See full document
11
Herpes Simplex Virus 1 UL47 Interacts with Viral Nuclear Egress Factors UL31, UL34, and Us3 and Regulates Viral Nuclear Egress
... this type of virion was substan- tially ...of viral egress from the nucleoplasm decreased in the absence of UL47 compared to that in the presence of UL47, but the rate of egress from the perinuclear space ... See full document
11
Herpes Simplex Virus type 1 lytic viral gene expression during the establishment and maintenance of latency
... whole viral genome preparation used was approximately 61 plaques per µg of DNA (data not shown), less than the 100-1000 plaques per µg of viral DNA recommended for the generation of recombinant HSV-1 ... See full document
353
Release of the catalytic domain N(o) from the herpes simplex virus type 1 protease is required for viral growth.
... UL26 gene under its own promoter (pRB4057 or pM307L) or the simian virus 40 early gene pro- moter (pSVPra) complemented the growth of ...for viral replication, since the cleavage site mutant ... See full document
9
Identification and Characterization of the UL56 Gene Product of Herpes Simplex Virus Type 2
... UL56 gene product of herpes simplex virus (HSV) has been shown to play an important role in viral ...HSV type 2 (HSV-2) and examined its expression and properties. The ... See full document
11
ICP22 Is Required for Wild-Type Composition and Infectivity of Herpes Simplex Virus Type 1 Virions
... Because gene regulation is al- tered in 22/n199-infected Vero cells relative to wild-type virus (30, 37), the availability of viral proteins for virion formation is also ...of viral ... See full document
10
Transcriptional Coactivators Are Not Required for Herpes Simplex Virus Type 1 Immediate-Early Gene Expression In Vitro
... IE gene expression in HFFs in which the expression of BRM and Brg-1 remodeling enzymes was disrupted by RNAi, with the expectation that IE gene expression would diminish in the absence of BRM and ... See full document
14
A temperature-sensitive mutation in a herpes simplex virus type 1 gene required for viral DNA synthesis maps to coordinates 0.609 through 0.614 in UL.
... At the nonpermissive temperature, ts701 i failed to induce the synthesis of viral DNA, ii exhibited a dramatically reduced ability to drive replication of a plasmid containing the herpes[r] ... See full document
7
Functional Hierarchy of Herpes Simplex Virus 1 Viral Glycoproteins in Cytoplasmic Virion Envelopment and Egress
... Herpes simplex virus 1 (HSV-1) viral glycoproteins gD (carboxyl terminus), gE, gK, and gM, the membrane protein UL20, and membrane-associated protein UL11 play important roles in ... See full document
9
The product of the UL12.5 gene of herpes simplex virus type 1 is a capsid-associated nuclease.
... replicated viral DNA prior to its packaging into ...of viral polypeptides which play a role in this encapsidation process have been identified (reviewed in refer- ence 23), the actual protein which performs ... See full document
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