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Identification of Hub genes and key pathways associated with atopic

Identification of Hub genes and key pathways associated with atopic

... Taken together, the top 200 protein genes acquired from Open Targets Platform and later integrated analysis. 284[r] ... See full document

64

<p>Identification of hub genes and key pathways associated with angioimmunoblastic T-cell lymphoma using weighted gene co-expression network analysis</p>

<p>Identification of hub genes and key pathways associated with angioimmunoblastic T-cell lymphoma using weighted gene co-expression network analysis</p>

... 5468 genes with dissimilarity based on the topological overlap together with the assigned module ...random genes from the network using a heatmap plot to depict the TOM among the genes in the ... See full document

12

&lt;p&gt;Identification of key genes and pathways in Ewing&amp;rsquo;s sarcoma patients associated with metastasis and poor prognosis&lt;/p&gt;

<p>Identification of key genes and pathways in Ewing&rsquo;s sarcoma patients associated with metastasis and poor prognosis</p>

... childhood and adolescence. 3,4 ES mainly occurs in bone and surrounding soft tissue characterized by a highly aggressive small round blue cell malignant neoplasm. 5,6 Accumulating evidence strongly documented that ... See full document

13

Identification of key pathways and genes influencing prognosis in bladder urothelial carcinoma

Identification of key pathways and genes influencing prognosis in bladder urothelial carcinoma

... and pathways, including TP53 and mitotic ...fifty-six genes were identified as potential prognosis-related ...of Genes and Genomes analyses showed that the potential prognosis-related DEGs were ... See full document

14

Prediction of key genes and pathways involved in trastuzumab resistant gastric cancer

Prediction of key genes and pathways involved in trastuzumab resistant gastric cancer

... a key cancer stem cell (CSC) marker, was downreg- ulated in trastuzumab-resistant breast cancer and associated with the trastuzumab resistance in ...top hub gene in PPI networks of ... See full document

12

Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis

Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis

... upregulated genes and 17 downregulated genes, which were mainly enriched in biological processes associated with oxidation–reduction ...of Genes and Genomes pathways including chemical ... See full document

9

&lt;p&gt;Identification of key genes and pathways in seminoma by bioinformatics analysis&lt;/p&gt;

<p>Identification of key genes and pathways in seminoma by bioinformatics analysis</p>

... Interacting Genes (STRING) is a biological database for building protein – protein interac- tion (PPI) networks, providing a system-wide view of inter- actions between each ...proteins, genes, and other ... See full document

11

&lt;p&gt;Identification of key genes, pathways and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis&lt;/p&gt;

<p>Identification of key genes, pathways and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis</p>

... of Genes and Genomes (KEGG) database, these differ- entially expressed genes (DEGs) were significantly enriched in the following signaling pathways and processes, such as the MAPK signaling pathway, ... See full document

16

Identification of key genes and pathways involved in response to pain in goat and sheep by transcriptome sequencing

Identification of key genes and pathways involved in response to pain in goat and sheep by transcriptome sequencing

... functions associated with gated channel activity, N-methyl-d-aspartate (NMDA) receptor, inflamma- tory response, immune response, and defense response (Table 1 and ...3). Key DEGs such as C-C motif ... See full document

11

Identification of key genes and pathways using bioinformatics analysis  in septic shock children

Identification of key genes and pathways using bioinformatics analysis in septic shock children

... 10 hub genes with higher degrees were individually screened via Cytoscape ...enriched pathways of the DEGs involved in the modules were ...mainly associated with chemokine signaling ...the ... See full document

12

&lt;p&gt;Identification of Potential Key Genes and Pathways for Inflammatory Breast Cancer Based on GEO and TCGA Databases&lt;/p&gt;

<p>Identification of Potential Key Genes and Pathways for Inflammatory Breast Cancer Based on GEO and TCGA Databases</p>

... downregulated genes, were identi fi ed from four GEO datasets of ...strongly associated with multiple cancer-related functions and pathways, such as cell adhesion, cell proliferation, Wnt, PI3K-AKT, ... See full document

10

Original Article Identification of key pathways and candidate genes in gliomas by bioinformatics analysis

Original Article Identification of key pathways and candidate genes in gliomas by bioinformatics analysis

... 10 pathways. GZMB, CD48, and GZMA were screened as the top 3 hub genes in protein- protein interaction ...candidate genes and pathways by bioinformatics analysis, this study sheds light ... See full document

14

Identification of key pathways and genes in &lt;em&gt;TP53 &lt;/em&gt;mutation acute myeloid leukemia: evidence from bioinformatics analysis

Identification of key pathways and genes in <em>TP53 </em>mutation acute myeloid leukemia: evidence from bioinformatics analysis

... generation sequencing techniques to detect TP53 mutations in blood or bone marrow before any chemotherapy and demonstrated a potential mechanism whereby hematopoietic stem/progenitor cells with heterozygous TP53 ... See full document

11

Original Article Mutual information network-based support vector machine for identification of rheumatoid arthritis-related genes

Original Article Mutual information network-based support vector machine for identification of rheumatoid arthritis-related genes

... significant genes in the pathogenesis of rheumatoid arthritis (RA) have greatly aroused the interest of clinicians and ...expressed genes (DEGs) identification was ...differential pathways ... See full document

8

Identification of potential key genes associated with ovarian clear cell carcinoma

Identification of potential key genes associated with ovarian clear cell carcinoma

... expressed genes (DEGs) between OCCC tumor and normal ovary ...of Genes and Genomes pathway enrichment analysis were performed using the g:Profiler database and ...Interacting Genes, we performed ... See full document

10

Identification of hub genes with prognostic values in gastric cancer by bioinformatics analysis

Identification of hub genes with prognostic values in gastric cancer by bioinformatics analysis

... In recent years, the application of high-throughput platforms in gene expression (GE) is becoming more valuable in clinical research, like molecular classification, prognosis prediction, and new targeted drug discovery ... See full document

12

Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses

Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses

... Hub genes, regulatory transcription factors and micro- RNAs in the entorhinal cortex tissues of mid-stage AD cases have been identified via analyzing the database of GSE4757 and therapeutic targets or ... See full document

13

&lt;p&gt;Identification of key pathways and hub genes in basal-like breast cancer using bioinformatics analysis&lt;/p&gt;

<p>Identification of key pathways and hub genes in basal-like breast cancer using bioinformatics analysis</p>

... Human Genome U133A Array) contains 508 BC samples, and the gene expression profiles of GSE21422 containing five healthy breast tissues and five invasive ductal breast carcinoma (IDC) samples were deposited in the GPL6244 ... See full document

13

Identification of key pathways and genes with aberrant methylation in prostate cancer using bioinformatics analysis

Identification of key pathways and genes with aberrant methylation in prostate cancer using bioinformatics analysis

... (16 genes), zinc ion binding (seven genes), metal ion binding (eight genes), DNA binding (six genes) and receptor activity (six ...candidate genes were associated with cytoplasm ... See full document

9

&lt;p&gt;Identification of Chemoresistance-Associated Key Genes and Pathways in High-Grade Serous Ovarian Cancer by Bioinformatics Analyses&lt;/p&gt;

<p>Identification of Chemoresistance-Associated Key Genes and Pathways in High-Grade Serous Ovarian Cancer by Bioinformatics Analyses</p>

... the hub gene, which may be a potential therapeutic target in ...of hub genes in this study were discovered, the top three of which were KIT, FOXM1, and ...second hub gene, FOXM1, a ... See full document

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