[PDF] Top 20 Incidence and Timing of Presentation of Necrotizing Enterocolitis in Preterm Infants

... cuss the multifactorial pathogenesis of NEC and suggest the complex interplay between immature gastrointestinal tract with associated immature muco- sal barrier, immune defense, circulatory regulation, altered ... See full document

... premature infants [82] ...premature infants, routine admi- nistration of probiotic agents has elicited substantial controversy regarding the type of agent to be used, dosing and timing [83] ...and ... See full document

... In the analysis of trials evaluating a specific interven- tion, it is pivotal to understand whether the results of these trials are generalizable or applicable only in spe- cific clinical settings. According to our data, ... See full document

... Preterm infants are highly susceptible to life-threatening infections that are clinically difficult to detect, such as late-onset septicemia and necrotizing enterocolitis ...clinical ... See full document

... the incidence of NEC in the probiotic group was significantly low (p= ...the incidence of NEC was lower in the multiple strain group and Lactobacillus group with a P value of p= ...The incidence of ... See full document

... LOSD feeding protocol not only offers cautious chal- lenge to the immature intestine but also may offer total intestinal hygiene. The longer initiation time, smaller feedings than described in most clinical studies, and ... See full document

... Although there are many narrative reviews, to our knowledge, this is the first systematic review and meta- analysis of microbial dysbiosis preceding NEC. Our review supports the hypothesis that intestinal dysbiosis with ... See full document

... 3. Van Niekerk E, Autran CA, Nel DG, et al. Human milk oligosaccharides differ between HIV- infected and -uninfected mothers and are related to necrotizing enterocolitis incidence in their ... See full document

... While early colonization might contribute in various ways to the causal pathway leading to NEC, our findings are consistent with the suggestion that early dysbiosis has a time-sensitive role in dysregulation of the ... See full document

... The incidence of culture-proven neonatal sepsis and necrotizing enterocolitis (NEC) in preterm infants maintained at pharmacologic (mean 5.1 mg/dL ± 1.45 SD) serum vitamin E levels for l[r] ... See full document

... overall incidence of necrotizing enterocolitis/septicemia in preterm infants.47 Administration of enteral nutrition with a glutamine enriched formula 30.5 g/100 g protein feeding resulte[r] ... See full document

... were collected either on or after the day of onset of clinical signs of NEC and after the introduction of antibiotic therapy. The identities of the cultured bacterial isolates and of those isolates presumptively ... See full document

... in Preterm Infants Born in a Perinatal Unit as Detected by Serial Real-Time Incidence, Severity, and Timing of Subependymal and Intraventricular Hemorrhages. Services[r] ... See full document

... VLBW infants admitted to our NICU during the ...these infants, 50 expired (n ⫽ 42) or had NEC before 7 days after birth (n ⫽ 6) or the family members declined consent for study (n ⫽ ...367 infants ... See full document

... among infants with surgical NEC because of poor weight gain sec- ondary to increased metabolic needs imposed by NEC, BPD, or infection, their discharge weights were significantly greater than their ...NEC ... See full document

... term infants with necrotizing enterocolitis ...Forty-two preterm infants were selected for fecal sample analy- sis, including 21 preterm infants with NEC and 21 healthy ... See full document

... demonstrated that SIGIRR inhibited in fl ammation induced by lipopolysaccharide, a cell wall component of Gram-negative bacteria implicated in NEC. The genetic variants identified in the infant with NEC resulted in loss of ... See full document

... promote viability and differentiation of neuronal cells. Moreover, a number of aforementioned NEC-associated CSF cytokines (Additional file 1: Figure S2) are known to promote neurite outgrowth, including INF-γ [42], ... See full document

... PCR studies of amniotic fluid have estimated the prevalence of microbial invasion of the amniotic cavity to be more than 30–50% higher than previously detected by culture based methods (DiGiulio 2012). The placental ... See full document

... sized that maternal variables are the primary factor that affect fetal de- velopment and that these correlate with future development of NEC. We speci fi cally thought that maternal risk factors such as smoking, age, ... See full document