[PDF] Top 20 Influence of human T-cell leukemia virus type I tax and rex on interleukin-2 gene expression.
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Influence of human T-cell leukemia virus type I tax and rex on interleukin-2 gene expression.
... 67, 1993 HTLV-I tax AND rex INFLUENCE ON IL-2 GENE EXPRESSION structs also confirm this observation, because expression of tax and rex in those experiments is promoted by the HTLV-I DISC[r] ... See full document
10
Phosphorylation regulates human T cell leukemia virus type 1 Rex function
... The Rex-1 expression vector SE356, which contains the HTLV-1 tax/rex cDNA expressed from the cytomegalovirus (CMV) immediate-early gene promoter, was described previously ...S-tagged ... See full document
11
Phosphorylation of Two Serine Residues Regulates Human T-Cell Leukemia Virus Type 2 Rex Function
... Plasmids. Rex expression vector BC20.2, containing HTLV-2 tax/rex cDNA expressed from the cytomegalovirus (CMV) immediate-early gene promoter, has been described earlier (14, ... See full document
10
Mutational analysis of human T-cell leukemia virus type 2 Tax.
... Human T-cell leukemia virus type 1 (HTLV-1) and type 2 (HTLV-2) contain at least two trans-regulatory genes, tax and rex (23, 27, 39, ...Both ... See full document
6
Activation of Human T-Cell Leukemia Virus Type 1tax Gene Expression in Chronically Infected T Cells
... Fluorescence-activated cell sorter analysis of T-cell surface markers present on the different chronically infected cell lines demonstrated that CD3 expression was restricted to FS and ... See full document
7
Role of Tax protein in human T cell leukemia virus type I leukemogenicity
... adult T-cell leukemia (ATL), the neurological syndrome TSP/ HAM and certain other clinical ...viral Tax protein is considered to play a central role in the process leading to ...ATL. ... See full document
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The human T-cell leukemia virus type I Tax protein induces apoptosis which is blocked by the Bcl-2 protein.
... Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death.. Adult T-cell leukemia antigen in an ATL cell line and[r] ... See full document
6
Human T-Cell Leukemia Virus Type 2 Rex Carboxy Terminus Is an Inhibitory/Stability Domain That Regulates Rex Functional Activity and Viral Replication
... active Rex-2 mutants, A157D and S158Term, led to increased pro- duction of p19 Gag as measured in the culture supernatant, ultimately increasing HTLV-2 infectious spread and HTLV-2- mediated ... See full document
12
Human T-Cell Leukemia Virus Type 1 Tax Protein Abrogates Interleukin-2 Dependence in a Mouse T-Cell Line
... HTLV-1-transformed T-cell lines in the ab- sence of IL-2. Two types of T-cell lines are transformed by HTLV-1; one is IL-2 dependent, and the other is IL-2 inde- ...Since ... See full document
7
Human T-Cell Leukemia Virus Type 1 Tax Relieves Repression of Proliferating Cell Nuclear Antigen Gene Expression
... of Tax-mediated transactivation of the TATAA- less PCNA ...(Student t test; P ⬍ 0.05). (B) Western blot of 293 whole-cell extracts from mock-transfected cells (lane 1) or cells transfected with ... See full document
9
Interleukin 1 gene expression in adult T cell leukemia
... adult T cell leukemia (ATL) is a T cell neoplasm etiologically associated with human T lymphotropic virus type I (HTLV-I) ...express ... See full document
7
Inhibition of human T-cell leukemia virus type 2 Rex function by truncated forms of Rex encoded in alternatively spliced mRNAs.
... the Rex/RXRE regulatory pathway of HTLV, the HIV-1 Rev protein activates the expression of unspliced and singly spliced HIV-1 mRNAs through interaction with an RNA target termed the Rev-responsive element ... See full document
9
Silencing of human T cell leukemia virus type I gene transcription by epigenetic mechanisms
... and tax gene transcription was analyzed ...of tax gene transcripts (Case 1, 9, 12, 20), 5'-LTR was not methylated or slightly ...higher expression of tax gene is asso- ... See full document
16
Stimulation of alpha 1 (I) procollagen gene expression in NIH 3T3 cells by the human T cell leukemia virus type 1 (HTLV 1) Tax gene
... the expression of genes encoding extracellular matrix proteins in fibroblasts and other mesenchymal cells have remained ...that Tax, a trans-regulatory protein from the human T cell ... See full document
9
Nuclear Export and Expression of Human T-Cell Leukemia Virus Type 1 tax/rex mRNA Are RxRE/Rex Dependent
... that Rex-mediated nucleocy- toplasmic export of viral RNA requires binding to human chro- mosomal region maintenance 1 (hCRM1; also known as exportin 1 [XPO1]) (18), a member of the importin family, in ... See full document
7
Transrepression of lck gene expression by human T-cell leukemia virus type 1-encoded p40tax.
... the expression vector DNA was found to be present in 7 and 3 out of 100 clones obtained after transfection with pMTEX or MT-Tax, ...SV40-Neo expression vector; JK C11-pM- TEX, stably cotransfected by ... See full document
9
Costimulation of cytokine gene expression in T cells by the human T leukemia/lymphotropic virus type 1 trans activator Tax.
... cellular gene expression appears to be associated with the virus-encoded trans-activat- ing protein p40x, or Tax, and overexpression of Tax in unin- fected cells is sufficient for the ... See full document
8
Human T cell leukemia virus type I Tax induces the expression of CD83 on T cells
... Phenotypic analyses of cells were carried out using polychromatic flow cytometry (FCM) as reported pre- viously [26]. Briefly, live cells were Fc-blocked with 2 mg/ml pooled normal human IgG in FACS buffer ... See full document
13
The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes.
... HTLV-induced T-cell transformation re- mains ...adult T-cell leukemia do so after a 25- to 30-year latent ...and Tax expression are low or absent in leukemic cells, ... See full document
9
Human T cell leukemia virus type 2 Tax protein induces interleukin 2 independent growth in a T cell line
... mouse T- cell line CTLL-2 from an interleukin(IL)-2-dependent growth to an IL-2-independent one, whereas Tax2 can not do so ...the tax gene which is much more ... See full document
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