[PDF] Top 20 Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat.
Has 10000 "Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat." found on our website. Below are the top 20 most common "Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat.".
Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat.
... intact Tax protein that was not possible with short induction at 37 8 C using high concentrations of ...of 1 min ...imidazole. Tax protein was then eluted with a 60-ml gradient of 80 to 300 mM ... See full document
7
Function of the human T-cell leukemia virus type 1 21-base-pair repeats in basal transcription.
... The Tax protein is a potent stimulator of viral transcription (5, 12, 38) and is the transforming protein of HTLV-1 (19–21, 30, 35, ...41). Tax does not bind DNA directly but rather ... See full document
8
Chimeric proteins composed of Jun and CREB define domains required for interaction with the human T-cell leukemia virus type 1 Tax protein.
... of Tax to stimulate CREB binding to the 21-bp repeat has been demon- strated in several studies (1, 4, 19, 45, 59, 62, 66, ...of CREB binding is due to the stable interac- tion ... See full document
10
The oncoprotein Tax of the human T-cell leukemia virus type 1 activates transcription via interaction with cellular ATF-1/CREB factors in Saccharomyces cerevisiae.
... of Tax/ATF-1/ CREB in yeast cells through expression of b -galactosidase driven by a yeast minimal promoter containing ATF-1/CREB binding sites within two HTLV-1 21-bp ... See full document
7
Tax Interacts with P-TEFb in a Novel Manner To Stimulate Human T-Lymphotropic Virus Type 1 Transcription
... Human T-lymphotropic virus type 1 (HTLV-1) is the caus- ative agent of adult T-cell leukemia and the neurological disorder HTLV-1-associated ... See full document
11
Coactivator-Associated Arginine Methyltransferase 1 Enhances Transcriptional Activity of the Human T-Cell Lymphotropic Virus Type 1 Long Terminal Repeat through Direct Interaction with Tax
... of Tax. Since CARM1 is important for Tax transactivation of the HTLV-1 LTR and CARM1 directly binds to Tax, we next tested whether Tax recruits CARM1 to the HTLV-1 PICs ...the ... See full document
9
Interaction of Gli2 with CREB Protein on DNA Elements in the Long Terminal Repeat of Human T-Cell Leukemia Virus Type 1 Is Responsible for Transcriptional Activation by Tax Protein
... terminal repeat (LTR) of human T-cell leukemia virus type 1 (HTLV-1) has two distinct DNA ele- ments, one copy of TRE2S and three copies of a 21-bp sequence that ... See full document
6
Human T-Lymphotropic Virus Type 1 p30IIFunctions as a Transcription Factor and Differentially Modulates CREB-Responsive Promoters
... Human T-lymphotropic virus type 1 (HTLV-1) is a complex retrovirus that encodes typical gag, pol, and env gene products as well as unique regulatory and accessory genes ... See full document
8
Selective infection of human T-lymphotropic virus type 1 (HTLV-1)-infected cells by chimeric human immunodeficiency viruses containing HTLV-1 tax response elements in the long terminal repeat.
... 60). Tax does not bind directly to DNA (24, 45); instead its effects are me- diated through the action of cellular transcription factors, par- ticularly those of the ATF/CREB family (2, 24, 30, 64, 67, ... See full document
10
Distinct regions in human T-cell lymphotropic virus type I tax mediate interactions with activator protein CREB and basal transcription factors.
... for CREB interaction is further emphasized by a pre- vious report showing its involvement in determining the spec- ificity of HTLV-I Tax and HTLV-II Tax for activating the respective ... See full document
8
Transactivation of the human T-cell lymphotropic virus type 1 Tax1-responsive 21-base-pair repeats requires Holo-TFIID and TFIIA.
... TFIID has been shown to be functionally heterogeneous, as a result of the interaction of specific TAFs (66). Following phosphocellulose fractionation of HeLa extracts, TFIID is lo- cated in both the 0.3 and 0.85 M ... See full document
10
Human T-Lymphotropic Virus Type 1 Oncoprotein Tax Promotes S-Phase Entry but Blocks Mitosis
... when tax-transduced PA18G-BHK-21 cells were examined under the microscope 1 week after puro- mycin selection, many giant cells–-each containing an enlarged cytoplasm and multiple nuclei and with a ... See full document
12
Induction of p21CIP1/WAF1expression by human T lymphotropic virus type 1 Tax requires transcriptional activation and mRNA stabilization
... by Tax may be causally linked to the activity of the APC/C E3 ...by Tax appear correlated [27], the stabilization of p21 may be a result of IKK or NF-κB ...their interaction with mRNA is facili- ... See full document
13
Oncogenic Human T-Cell Lymphotropic Virus Type 1 Tax Suppression of Primary Innate Immune Signaling Pathways
... HTLV-1 Tax potently inhibits antiviral signaling by one of these important ...of type I IFNs in response to cytosolic viral RNA species (10, ...HTLV-1 Tax inhibits the production ... See full document
14
Human T-Lymphotropic Virus Type 1 Mitochondrion-Localizing Protein p13II Is Required for Viral Infectivity In Vivo
... primer pair specific for the HTLV-1 tax region at final concentrations of 300 nM each of forward and reverse primers and 200 nM of a dually labeled probe as previously described ...; tax ... See full document
8
Costimulation of cytokine gene expression in T cells by the human T leukemia/lymphotropic virus type 1 trans activator Tax.
... that Tax may in part mimic the physiological signal from CD28, experiments with Tax pro- tein mutants showed that factors in addition to NF- k B/rel are involved in the response of GM-CSF and IL-2 to ... See full document
8
CREB/ATF-Dependent Repression of Cyclin A by Human T-Cell Leukemia Virus Type 1 Tax Protein
... the human T-cell leukemia virus type 1 (HTLV-1) oncoprotein Tax is correlated with cellular transformation contributing to the development of adult T-cell ... See full document
13
Multistep regulation of enhancer activity of the 21-base-pair element of human T-cell leukemia virus type I.
... 4348 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest We examined the regulatory mechanisms of binding and transcriptional enhancement of the 21-bp core element of the en[r] ... See full document
10
Cell-Free versus Cell-to-Cell Infection by Human Immunodeficiency Virus Type 1 and Human T-Lymphotropic Virus Type 1: Exploring the Link among Viral Source, Viral Trafficking, and Viral Replication
... to T cells after DC cis-infection,” ...The virus then “surfs” outside the plasma membrane using actin-dependent polarized movements and accumulates in invaginated domains continuous with the plasma membrane ... See full document
11
Major Histocompatibility Complex Class II Transactivator CIITA Is a Viral Restriction Factor That Targets Human T-Cell Lymphotropic Virus Type 1 Tax-1 Function and Inhibits Viral Replication
... Transient transfections, Luciferase assay, and Western blotting. COS and 293T cells were seeded in 35-mm-diameter plates and transfected with 0.15 g of reporter plasmid pLTR1-Luc, 12.5 ng of pTax-1, and ... See full document
11
Related subjects