[PDF] Top 20 Interplay of RNA Elements in the Dengue Virus 5′ and 3′ Ends Required for Viral RNA Replication
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Interplay of RNA Elements in the Dengue Virus 5′ and 3′ Ends Required for Viral RNA Replication
... of RNA replication of replicon RNAs harboring the 3 ⬘ NoDAR mutation was due to interference with HP-3 ⬘ SL formation, we introduced additional mutations into the 3 ⬘ sequence to ... See full document
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RNA Secondary Structure in the Coding Region of Dengue Virus Type 2 Directs Translation Start Codon Selection and Is Required for Viral Replication
... are required for viral ...are required for the DENV2 viral life cycle, the first and second AUGs were mutated (pD2/IC-AUG1mut and pD2/IC- AUG2mut, respectively) ...with viral ... See full document
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The 5′-Terminal Region of the Aichi Virus Genome Encodes cis-Acting Replication Elements Required for Positive- and Negative-Strand RNA Synthesis
... Aichi virus is a member of the family ...the 5 ⴕ end) formed at the 5 ⴕ end of the genome are critical elements for viral RNA ...the 5 ⴕ -terminal cis-acting ... See full document
14
Structural and Functional Studies of the Promoter Element for Dengue Virus RNA Replication
... the virus replicated with two mismatches within this region ...is required for efficient viral replication, certain mismatches are ...the 5 ⬘ UTR and pathogenesis was previously ... See full document
16
Overlapping Local and Long-Range RNA-RNA Interactions Modulate Dengue Virus Genome Cyclization and Replication
... engue virus (DENV) is a member of the Flaviviridae family that includes other important pathogens such as yellow fever virus (YFV), West Nile virus (WNV), Saint Louis encephalitis vi- rus (SLEV), and ... See full document
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Sequences in the 5′ Nontranslated Region of Hepatitis C Virus Required for RNA Replication
... the 5⬘ NTR are not required for IRES ...the 5⬘ end of a viral RNA genome are very important determinants for replication, we anticipated that the same might be true for ... See full document
11
3′ RNA Elements in Hepatitis C Virus Replication: Kissing Partners and Long Poly(U)
... the replication efficien- cies of genomes with interspersed A or C nucleotides at vari- ous intervals throughout a 27-nt ...the 3 ⬘ region of the poly(U/ UC) tract, it was surprising that a genome with ... See full document
12
Role of the Hepatitis C Virus Core+1 Open Reading Frame and Core cis-Acting RNA Elements in Viral RNA Translation and Replication
... not required for viral replication (6, ...genome replication in tumor cells than in nontumor cells in- dicate that core ⫹ 1 might exert a negative effect on viral rep- ...HCV ... See full document
13
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3' ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 protein
... DNA replication/repair [31], regulation of his- tone genes expression [18], and modulation of telomere structure ...of Dengue virus suggesting that nuclear localization of NS5 may be via the ... See full document
10
Nuclear Localization of Dengue Virus Nonstructural Protein 5 Does Not Strictly Correlate with Efficient Viral RNA Replication and Inhibition of Type I Interferon Signaling
... efficient RNA replication, at least in cell culture. The replication deficiency of ␣ NLS mutants cannot be res- cued by ...is required in order to suppress the induction of antiviral ... See full document
13
Long-Range RNA-RNA Interactions Circularize the Dengue Virus Genome
... Nile virus, and Japanese encephalitis ...positive-strand RNA viruses, replication of flaviviruses proceeds along a two-step pathway in the host ...the viral RNA form a ... See full document
13
Poly(C)-Binding Protein 2 Interacts with Sequences Required for Viral Replication in the Hepatitis C Virus (HCV) 5′ Untranslated Region and Directs HCV RNA Replication through Circularizing the Viral Genome
... HCV 5 ⴕ UTR to determine the replication ...the 5 ⬘ UTR are required for RNA repli- cation, we constructed a series of mutant replicons in which combinations of the stem-loops of the ... See full document
11
The 5′ and 3′ Downstream AUG Region Elements Are Required for Mosquito-Borne Flavivirus RNA Replication
... on 5 ⬘ –3 ⬘ genome circularization, we used a previously described RNA binding assay in which interaction between two RNAs, one representing the 5 ⬘ end and the other the 3 ⬘ end, can ... See full document
6
Sequence and Structural Elements at the 3′ Terminus of Bovine Viral Diarrhea Virus Genomic RNA: Functional Role during RNA Replication
... Bovine viral diarrhea virus (BVDV), a member of the genus Pestivirus in the family Flaviviridae, has a positive-stranded RNA genome consisting of a single open reading frame and untranslated regions ... See full document
13
Non structural protein 1 is required for West Nile virus replication complex formation and viral RNA synthesis
... high viral yield that were seen with the complementing cell expressing WNV ...were required for trans-complementation of Δ-NS1 YFV with NS1 from heterologous flaviviruses [23], we sequenced the complete ... See full document
14
Different De Novo Initiation Strategies Are Used by Influenza Virus RNA Polymerase on Its cRNA and Viral RNA Promoters during Viral RNA Replication
... single-stranded RNA viruses to initiate and control their replication via the synthesis of replicative ...same virus-encoded polymerase is responsible for both genome and antigenome strand synthesis ... See full document
12
hnRNP A1 Interacts with the 5′ Untranslated Regions of Enterovirus 71 and Sindbis Virus RNA and Is Required for Viral Replication
... for 5 min and washed another three times with ...containing 5% bovine serum albumin for 60 min at room temperature and then incubated with anti-hnRNP A1 antibody (1:200) and anti-EV71 3A antibody (1:200) ... See full document
9
Differential RNA Sequence Requirement for Dengue Virus Replication in Mosquito and Mammalian Cells
... position 3 of the loop, which was the only one that tolerated changes in our mutational analysis ...the RNA tetraloop sequences identified in ribosomal RNAs from different organisms fall into either UNCG or ... See full document
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Inhibitory effect of small interfering RNA on dengue virus replication in mosquito cells
... Background: Dengue viruses (DENs) are the wildest transmitted mosquito-borne pathogens throughout tropical and sub-tropical regions ...Although RNA interference triggered by long-length dsRNA was considered ... See full document
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Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication
... DENV replication. Using three independent assays to measure virus replication, we showed that more than half of the RBPs tested appeared to be involved in some aspect of the viral life ... See full document
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