[PDF] Top 20 Ion Channels are Biological Devices
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Ion Channels are Biological Devices
... Power Supply = spatially nonuniform inhomogeneous Dirichlet Boundary Conditions Flows,. Non-ideal mixtures including Ca 2+.[r] ... See full document
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Ion Channels are Biological Devices, the Valves* of Cells Main Controllers of Biological Function
... RyR model of Gillespie is best worked out for ~ 120 solutions Selectivity of K Channel is studied in ~1 solution at infinite dilution K channel of Roux has atomic detail but is studied a[r] ... See full document
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Ion Channels are Biological Devices, the Valves* of Cells Main Controllers of Biological Function
... Depends Sensitively on Self-organized Structure and their Flexibility Induced Structure is Different in Different Solutions. so[r] ... See full document
57
Poisson-Nernst-Planck-Fermi theory for modeling biological ion channels
... row channels, because the classical model does not include the volume effect of ions, water, and voids, the correlation effect of ions, and the screening effect of ... See full document
12
Numerical methods for a Poisson-Nernst-Planck-Fermi model of biological ion channels
... semiconductor devices and ion channels, especially with sharp potentials at practical applied voltages ...for ion channel simulations provided that the relaxation parameter is appropriately ... See full document
16
The Simulation of Ionic Charge Transport in Biological Ion Channels: an Introduction to Numerical Methods
... row channels and possibly even wider channels. The interaction of ions with dielectric surfaces is definitely a local phenomenon related to the particle char- acter of the ions themselves. However, continuum ... See full document
103
Ion Channels are the Valves of Cells Ion Channels are Devices that Control Biological Function
... "Synthetic Nanopores as a Test Case for Ion Channel Theories: The Anomalous Mole Fraction Effect without Single Filing." Biophys.. "Intracellular Calcium Release Channels Me[r] ... See full document
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Ion Channels are the Valves* of Biological Function Main Controllers of Cellular Function
... Model has 5 charged amino acids found by mutation experiments to determine selectivity and permeation The model reproduces >100 data curves of RyR with 8 adjustable parameters (g[r] ... See full document
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Stochastic dynamics of remote knock on permeation in biological ion channels
... bath ion is still at the channel entrance, its main role being to reduce the height of the exit ...bath ion is centred on the end of the channel suggests that, following the escape of the permeating ... See full document
5
Ionizable side chains at catalytic active sites of enzymes
... The biological function of an enzyme usually takes place in infoldings (pockets) of the protein called catalytic active ...of ion channels that show the importance of the acid side chains in calcium ... See full document
12
Computational Issues in Modeling Ion Transport in Biological Channels: Self-Consistent Particle-Based Simulations
... the ion channel protein, using an updated MDRUN function that is added to GROMACS ...the ion channel protein, and exerts an outward force on any lipid atom that would be located ...the ion channel is ... See full document
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CROWDED CHARGES IN ION CHANNELS
... all devices and biological ...build devices and biological ...the devices and machines of ...into devices and indeed sometimes additional information is needed in the form of ... See full document
147
Ion channels as insecticide targets
... & Reenan, 2000). In the RNA editing process, post-transcrip- tional editing of pre-mRNAs, through the action of dsRNA adenosine deaminases, modifies adenosine (A) residues to inosine (I), which then alters the coding ... See full document
16
Coulomb blockade model of permeation and selectivity in biological ion channels
... of biological ion ...calcium/sodium channels, the blockade is strong, so that the ionic permeation process is closely analogous to low-temperature mesoscopic transport in quantum ...calcium ... See full document
15
Three-Dimensional Continuum Simulations of Ion Transport Through Biological Ion Channels: Effect of Charge Distribution in the Constriction Region of Porin
... the ion density over a specified volume, have been calculated for ompF and G119D, for a range of salt concentrations and applied ...predicted ion occupancies, since the effective fixed charge lining the ... See full document
6
Bob Eisenberg
... in ion permeation, selectivity, gating (with YunKyong Hyon and Chun) and to new subjects of water movement (with Yoichiro Mori and Chun) and vesicle formation and fusion (with Fred Cohen, Rolf Ryham, and ... See full document
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Single Ion Channels
... of biological function can now be studied in hundreds of (different types of) channel ...control ion channels as well as we can already control the devices of our semiconductor ... See full document
10
Modified Donnan potentials for ion transport through biological ion channels
... 共 2 兲 We require that the concentrations and potential in the baths are constant except in the immediate vicinity of the channel. This is the condition that 共 usually 兲 excludes the leaky membrane 关 case 共 1 兲兴 since in ... See full document
8
Self-organized enhancement of conductivity in biological ion channels
... of ion-ion interactions on channel conductivity is the “knock-on” mechanism proposed by Hodgkin and Keynes ...arriving ion knocks into the outermost ion within the channel, causing the trapped ... See full document
13
Charge fluctuations and their effect on conduction in biological ion channels
... the ion through the channel, and for coupling of the ion motion to the channel gating ...moving ion is stored as the energy of vibrational ...moving ion in a self-consistent manner to ... See full document
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