[PDF] Top 20 A short linear sequence in the pre-S domain of the large hepatitis B virus envelope protein required for virion formation.
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A short linear sequence in the pre-S domain of the large hepatitis B virus envelope protein required for virion formation.
... simian virus 40 (SV40) early promoter with deletions of pre-S1 codons 2 to 95 and 2 to 30, respectively, and were constructed from pSV45-96 and pSV45-31 (5), respectively, in two ...the S gene in the ... See full document
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Functions of the internal pre-S domain of the large surface protein in hepatitis B virus particle morphogenesis.
... The hepatitis B virus (HBV) is an enveloped DNA virus with a unique replication strategy (for a review, see reference 13) which causes acute and chronic infections of the liver in hu- ...The ... See full document
6
Inhibition of Duck Hepatitis B Virus Infection by a Myristoylated Pre-S Peptide of the Large Viral Surface Protein
... DHBV pre-S domain ...internal pre-S subdo- main, consisting of amino acids 30 to 115, constitutes the duCPD receptor binding ...this domain includes an essential, partially ... See full document
5
Mapping of Amino Acid Side Chains on the Surface of Hepatitis B Virus Capsids Required for Envelopment and Virion Formation
... core protein (class c⫹v⫺) inducing a specific and rather drastic defect: nucleocapsids formed by the slightly altered core proteins are no longer exported from cells as enveloped ...the envelope proteins ... See full document
7
Infection Process of the Hepatitis B Virus Depends on the Presence of a Defined Sequence in the Pre-S1 Domain
... of hepatitis B virus (HBV), the large envelope protein (L) plays a pivotal ...the pre-S2 domain of the L protein in viral ...the pre-S1 region in HBV ... See full document
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The small envelope protein is required for secretion of a naturally occurring hepatitis B virus mutant with pre-S1 deleted.
... a pre-S1 deletion. A virion containing a deletion between nt 2983 and 3167 in the pre-S1 ORF was discovered by PCR amplification of HBV DNA from the serum of an individual with chronic liver dis- ... See full document
6
Influence of a Putative Intermolecular Interaction between Core and the Pre-S1 Domain of the Large Envelope Protein on Hepatitis B Virus Secretion
... L envelope protein could interfere with small envelope protein secretion (7, 26, ...the S and L envelope proteins have been shown to be required for virion ... See full document
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Dual topology of the large envelope protein of duck hepatitis B virus: determinants preventing pre-S translocation and glycosylation.
... HBV pre-S domain. First, it should be noted that only short proline- rich motifs are common between the respective pre-S amino acid ...boxy-terminal pre-S amino ... See full document
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A Short N-Proximal Region in the Large Envelope Protein Harbors a Determinant That Contributes to the Species Specificity of Human Hepatitis B Virus
... human hepatitis B virus (HBV) have been elucidated in detail (28, 29), the way in which this hepatotropic virus infects host cells still remains ...mediate virion attachment to the ... See full document
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Fine Mapping of Pre-S Sequence Requirements for Hepatitis B Virus Large Envelope Protein-Mediated Receptor Interaction
... viral envelope proteins (34). These three envelope proteins are termed large (L), middle (M), and small (S) ...outer virus shell, which is embedded in an endoplasmic reticulum ... See full document
12
Role of the Pre-S2 Domain of the Large Envelope Protein in Hepatitis B Virus Assembly and Infectivity
... the pre-S2 domain still allowed viral ...L protein are not involved in virion ...the pre-S2 domain prevents the release of complete viral ...the pre-S ... See full document
6
Mutations in the Carboxyl-Terminal Domain of the Small Hepatitis B Virus Envelope Protein Impair the Assembly of Hepatitis Delta Virus Particles
... HBV S envelope proteins in HuH-7 cells was achieved by using the expression vector p123 ...and S proteins were mutated to ACG to eliminate the expression of all three envelope ...the S ... See full document
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Intracellular retention of surface protein by a hepatitis B virus mutant that releases virion particles.
... Hepatitis B virus (HBV) is a DNA virus with a circular genome of approximately ...the virus from the liver, become chronically infected, and serve as the reservoir for further ... See full document
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Use of Pre-S Protein-Containing Hepatitis B Virus Surface Antigens and a Powerful Adjuvant To Develop an Immune Therapy for Chronic Hepatitis B Virus Infection
... the S protein (major protein), the M protein, and the L protein (7, 16, ...27-kDa S proteins, 33-kDa and 36-kDa glycosylated M proteins, and nonglycosylated 39-kDa and ... See full document
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A pre-S gene chip to detect pre-S deletions in hepatitis B virus large surface antigen as a predictive marker for hepatoma risk in chronic hepatitis B virus carriers
... The pre-S chip was placed in a 24-well culture plate, soaked in ...For pre-hybridiza- tion, the chip was then gently shaken in microarray hybridization buffer (5× SSC, 1% blocking reagent (Roche), ... See full document
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Virus-neutralizing monoclonal antibody to a conserved epitope on the duck hepatitis B virus pre-S protein.
... In this paper, we describe a DHBV-specific monoclonal antibody with neutralizing activity which binds to a conserved epitope present on the major 36-kDa protein and several smaller DHBV [r] ... See full document
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The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion
... while virion mor- phogenesis takes place on the membranes of the intracellular MVB, and the MVB transports virions to the plasma membrane and releases the virus through exocytosis (10, ...host ... See full document
13
Mutational analysis of the cysteine residues in the hepatitis B virus small envelope protein.
... Of four mutants involving the eight cysteines located in the antigenic region, only the double mutant lacking Cys.121 and Cys-124 was secreted with wild-type efficiency.. Secretion-compe[r] ... See full document
10
Apolipoprotein E but Not B Is Required for the Formation of Infectious Hepatitis C Virus Particles
... M-PER protein extraction reagent ...with protein G-conju- gated agarose beads (Invitrogen) bound with normal mouse IgG or apoB- or apoE-specific ...NS5A protein was subsequently detected by Western ... See full document
13
Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice.
... We draw this conclusion on the basis of our observations that i the HBsAg concentration in serum shows an inverse relationship with the intracellular large envelope polypeptide concent; [r] ... See full document
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