[PDF] Top 20 Microfluidic Approaches for Cancer Cell Separation: Review
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Microfluidic Approaches for Cancer Cell Separation: Review
... using cell line mixtures demonstrated a capture recovery rate greater than 94% and the capability to cul- tivate the captured cells on ...integrated microfluidic devices capable of cancer cell ... See full document
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Microfluidic Advancements in Classical Biotechnology – A Review
... products. Microfluidic-based techniques for the study of cell bioprocessing ...e.g. cell separation and cell lysis are well developed and documented in the ...current ... See full document
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Title: APPROCHES TO REDUCE TOXICITY OF ANTICANCER DRUG Author: Shweta Dutta*, Debashish Paramanick, Kamal Babu Aditya, Vijay Kumar Singh and Deepak Kumar Dash Keyword: Cancer, Polymeric Drug, Passive Targeting, Approaches, ToxicityPage No: 61-71DOI: 10.30876/JOHR.7.3.2018.61-71Abstract: Around the world, remarkable resource is being investigated for in prevention, diagnostic and treatment of cancer. Cancer is second leading cause of death. The current approach to treat cancer by main ly chemotherapy agent, radiation and surgery, but main obstacle is to lack of selectivity result in toxicity to non cancerous proliferative cell .conventional anticancer drug exhibit much toxic effect in the body. So in this review focus approaches to treat cancer with minimum adverse effect. The possible approaches regarding, site specific drug targeting by polymeric drug, ligand conjugated drug which directly binding to cancer cell by cancer targeting receptor. Also discuss about chemoprotective agent, dose reduction intermittent therapy and drug polymer which help to help reduce toxicity. Unique challenge and opportunity in these work help to anticancer drug development. Keywords: Cancer, Polymeric Drug, Passive Targeting, Approaches, Toxicity Download PDF
... commonly used non-ionic polymer in the field of polymer based drug delivery. Due to high aqueous solubility PEG polymer is considered as a adaptable candidate for the prodrug conjugation. Ringworm was the first propose ... See full document
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Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices
... acoustic approaches, where the radiation force changes with time, have gained increasing interest for particle ...fluorescence-activated cell sorting (FACS) techniques [13, 19] or for pat- terning ...binary ... See full document
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Microfluidic DNA amplification - a review
... developed microfluidic technologies. For example, microfluidic PCR can achieve rapid heat transfer, due to a large surface-to-volume ratio and fast mixing can be achieved by diffusion, due to its small ... See full document
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Tapered microfluidic device for multi particle separation based on sedimentation principle
... label-free separation approach is widely accepted enabling the birth of microfluidic ...technology. Microfluidic devices have emerged as multi-functional and powerful platform for separation ... See full document
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Systemic therapy for operable stage of non-small cell lung cancer, a short review of the main approaches
... Lung Cancer (WCLC) and revealed a 41% response rate to chemotherapy with a median follow-up of 64 month (HR for death = ...of Cancer (EORTC) 08012 trial ... See full document
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Particle separation in microfluidic devices - SPLITT fractionation and microfluidics
... This review paper focuses on field-flow fractionation (FFF) and split-flow-thin fractionation (SPLITT) and shows how these techniques can be applied to integrated microfluidic ...ultrasonic cell ... See full document
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Targeted treatments for cervical cancer: a review
... Cervical cancer is the second most common cause of cancer death in women world- wide and the development of new diagnosis, prognostic, and treatment strategies merits special ...stage cancer, the ... See full document
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Phase separation of multiphase droplets in a digital microfluidic device
... In recent years, solvent extraction and partitioning pro- cesses have been miniaturized into lab-on-a-chip devices due to their favorable position in terms of better mass transfer efficiency, higher specific interfacial ... See full document
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Formal Verification of a Microfluidic Device for Blood Cell Separation
... flow microfluidic device with IDT ...a microfluidic device employing DEP for purposes of sorting cells; the model is numerically solved and experimentally ...a microfluidic device that employs ... See full document
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Design and Verification of a Blood Cell Separation Microfluidic Device
... Abstract—Blood cell separation microdevices are designed in biomedical engineering for the separation of particular cells from blood, such as cancer ...flow microfluidic device is ... See full document
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A Review of Various Approaches for Cancer Diagnposis using Histological Images
... common cell advance has a far-reaching span of ...oppose cell downfall, replicative eternality permitting, angiogenesis instigating and initiating intrusion and metastasis can shape an immediately mass-time ... See full document
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Cancer Cell Metabolism: A Review
... the cancer cells has resulted in the augmentation of evidences that suggest an association of the several pathways of human metabolism with the cancer ...a cell to divide rapidly, it must be nutrient ... See full document
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Cancer Cell-Specific Oligopeptides Selected by an Integrated Microfluidic System from a Phage Display Library for Ovarian Cancer Diagnosis
... other cancer cells and collected by using an external ...phage-BG1 cell-magnetic beads complex in LB ...of cell culture, and it was found that the log growth phase was initiated by the 3 rd hour ... See full document
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Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages – a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape
... and cell migration were reported for neutrophils and initially attributed to the in- volvement of the A2 adenosine receptor ...pro-inflammatory cell types ...to cell type and activation ... See full document
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Cell Segmentation and Tracking in Microfluidic Platform
... the cell the same label with the track. Since the assignment between a cell and a track is a one to one relationship, a process of optimizing is essential when more than one cell tend to be ... See full document
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Design and Fabrication of Polydimethylsiloxane Based Low Cost Microfluidic for Ultra-Fast Diagnostic Applications
... small, microfluidic devices are easy to use, cheap to fabricate and operate, require very little sample, and they can be easily ...of microfluidic and is the inspiration for much of the research effort in ... See full document
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Early detection and personalized treatment in oral cancer: the impact of omics approaches
... present review, we focused on the contribution of genomic, epigenomic, transcriptomic, proteomic, meta- bolomic and lipidomic studies to the understanding and identifying of biomarkers capable of predict the ... See full document
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Prostate cancer imaging: positron-emission tomography perspectives
... Conventional approaches for anatomic imaging of prostate cancer include transrectal ultrasound, computed tomography (CT), and magnetic resonance imaging ...prostate cancer is limited, but it has an ... See full document
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