[PDF] Top 20 MicroRNAs in B cell development and malignancy
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MicroRNAs in B cell development and malignancy
... mature B cells [79-81]. Expression of miR-155 is rapidly induced in B cells after engagement of the antigen receptor and expo- sure to inflammatory mediators ...immune cell popu- lations; however, ... See full document
10
Cadherin mediated cell cell adhesion and tissue segregation in relation to malignancy
... of cell aggregate surface tensions, discussed above, have measured the intercellular bind- ing energies produced by direct, cadherin-mediated intercellular ...in development, then it is possible that α 5 β ... See full document
13
Plant microRNAs and development
... reproductive development, extra vegetative leaves and inflorescence axes and late flowering caused by the short integuments1 alleles (sin1 ; Robinson-Beers et ... See full document
12
The role of blood flow and microRNAs in blood vessel development
... vessel: the relative pulse slope index (RPSI). RPSI is significantly higher in arteries than veins. Experimentally lowering RPSI in pre- existing arterioles resulted in loss of arterial markers and emergence of venous ... See full document
12
Analysis of the mRNA Targetome of MicroRNAs Expressed by Marek’s Disease Virus
... cellular mRNAs, often encoding factors with antiviral potential, as well as in some cases regulating the expression of viral mRNAs, including mRNAs encoding factors involved in the latent-to-lytic transition of viral ... See full document
12
Discordant Reports of miRNA Expression in Cervical Cancer: An Upshot of Overlapping Factors
... others. MicroRNAs (miRNA) act by inhibiting messenger RNA (mRNA) in several biological processes, including proliferation, differentiation, development, metabolism and cell ... See full document
9
Role of stem cell proteins and microRNAs in embryogenesis and germ cell cancer
... confirmed cell type specificity for miR-302/367 expression; it is highly expressed in human ES and EC cells but not in adult human mesenchymal stem cells (hMSCs) and normal ...in development ... See full document
14
Second lung malignancy and Richter syndrome in chronic lymphocytic leukemia: case report and literature review
... cancer development is as- sociated with immunological impairment in CLL patients [18, ...normal B-cell pool, T cell subsets, natural killer cells and dendritic ...estingly, B CLL ... See full document
5
Differential expression of microRNAs in porcine parvovirus infected porcine cell line
... of microRNAs play an important role in regulating immune-related gene ...the development of new control strategies to prevent or treat PPV infections in ... See full document
8
Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy
... p300 to acetylate a given TF and affect its activity has been investigated (summarized in Table 2). There are four general ways that direct acetylation has been shown to affect TF function: 1) lysine acetylation can ... See full document
30
Therapeutic strategy with artificially-designed i-lncRNA targeting multiple oncogenic microRNAs exhibits effective antitumor activity in diffuse large B-cell lymphoma
... of B-cell chronic lymphocytic leukemia and observed a loss of expression of miR-15 and miR-16, thus providing the first evidence of an association between miRNAs and tumors ...tumor development and ... See full document
13
MicroRNAs as B-cell lymphoma biomarkers
... Abstract: B-cell lymphomas represent a group of more than 35 recognized mature B-cell neoplasms differentiated largely on the basis of immunohistochemical staining patterns that are often ... See full document
10
CHO microRNA engineering is growing up : recent successes and future challenges
... of cell lines has resulted in improved product quality (Huang et ...mammalian cell culture, such as the ef fi cient energy utilization (Zeng et ...2008). microRNAs have the advantage that they do not ... See full document
14
B cell selection and the development of autoantibodies
... (MZ) B cells did not increase [41]. Th e immature B cells expressed both TLR4 and TLR9 and proliferated after stimulation with either lipopolysac- charide (TLR4L) or CpG ...immature B cells to become ... See full document
13
Cell cell signaling and adhesion in phagocytosis and early development of Dictyostelium
... new, cell type specific, adhesion molecules or from quantitative differences in adhesion molecules common to both cell ...aggregative cell-cell adhesion, based on the fact that purified gp150 ... See full document
10
Checkpoints that control B cell development
... hematopoietic cell development ...and B-lymphoid developmental capac- ities (10) and can be found in embryonic primary lymphoid organs (11), it is not known whether or how they contribute to early ... See full document
9
The Role of Morphogens in B Cell Development
... including B cells, T cells, and ...“regulatory B cells” was first presented by Mizoguchi et al., 2000, in which B cells were able to suppress auto-immune disease in a mouse inflammatory bowel disease ... See full document
206
MicroRNAs of Epstein Barr Virus Attenuate T Cell Mediated Immune Control In Vivo
... B activation, compromising the type I IFN response, downregulating MHC-restricted antigen presentation, and changing a pro- into an anti- inflammatory environment ... B activation (26, ...T cell ... See full document
15
B cell antigen receptor isotypes : implications for immune memory
... memory B cells and long-lived plasma cells during TD responses (MacLennan, 1994; Kelsoe, ...1992) B cell blasts move from the boundary of the B/T cell zones into B cell ... See full document
248
MicroRNAs’ control of cancer cell dormancy
... cancer cell proliferation and ...avoid cell death induced by chemo- therapeutic agents, and thereby give rise to tumor relapse at a later ...of microRNAs. The present review highlights ... See full document
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